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Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Researchers from Ludwig-Maximilians-Universitaet in Munich have demonstrated, in a preclinical setting, the protective effect of a candidate vaccine directed against the coronavirus that causes Middle East Respiratory Syndrome. Planning for the first clinical trial is now underway.

22 Jun 2015

New book examines all aspects of HBV and HDV infections

Despite the availability of an effective vaccine for hepatitis B, hundreds of millions of people worldwide are infected with the hepatitis B virus (HBV). This virus can cause serious liver damage and cancer in chronically infected patients. Hepatitis delta virus (HDV), a satellite of HBV, can exacerbate the disease.

19 Jun 2015

Analysis of transportation data could help predict spread of flu epidemic across the U.S.

To predict how a seasonal influenza epidemic will spread across the United States, one should focus more on the mobility of people than on their geographic proximity, a new study suggests.

19 Jun 2015

Australian researchers launch global search to discover antibiotics against superbug bacteria

Australian researchers from The University of Queensland have launched a global search to discover antibiotics capable of combating superbug bacteria that are resistant to current antibiotics.

19 Jun 2015

Three studies describe advances toward development of antibodies to stop HIV

A trio of studies being published today in the journals Science and Cell describes advances toward the development of an HIV vaccine. The three study teams all demonstrated techniques for stimulating animal cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory or had the potential to evolve into such antibodies.

19 Jun 2015

Sequence of immunizations could be the promising route to HIV vaccine

The secret to preventing HIV infection lies within the human immune system, but the more-than-25-year search has so far failed to yield a vaccine capable of training the body to neutralize the ever-changing virus. New research from The Rockefeller University, and collaborating institutions, suggests no single shot will ever do the trick. Instead, the scientists find, a sequence of immunizations might be the most promising route to an HIV vaccine.

19 Jun 2015

Survey finds first evidence of MRSA in sausages, minced pork from supermarkets in the UK

A survey carried out earlier this year has found the first evidence of the 'superbug' bacteria Methicillin-Resistant Staphylococcus aureus (MRSA) in sausages and minced pork obtained from supermarkets in the UK. However, researchers stress that this does not pose a significant immediate risk to the public.

19 Jun 2015

New review highlights strategies to inhibit infections during the laundering process of HCT

Proper laundering and handling are important in achieving and maintaining the hygienically-clean quality of healthcare fabrics and textiles delivered to the point of care, according to a new review that highlights evidence-based strategies to inhibit potentially serious contamination.

19 Jun 2015

Experimental AIDS vaccine candidate stimulates immune system to block infection in animal model

New research led by scientists at The Scripps Research Institute, International AIDS Vaccine Initiative and The Rockefeller University shows that an experimental vaccine candidate can stimulate the immune system to block HIV infection in mice.

18 Jun 2015

Scientists create new model to study latent HIV infection in brain cells

Over 35 million people worldwide are currently infected by HIV. Antiviral therapies can keep the virus from multiplying. However, no drug can cure infection so far, because various cell types continue to carry the virus in a latent, i.e. quiescent, state. Scientists of Helmholtz Zentrum München have now established a model for latent HIV infection of brain cells.

18 Jun 2015

Key lessons from Middle East Respiratory Syndrome outbreak in South Korea

The outbreak of Middle East Respiratory Syndrome (MERS) in South Korea is the subject of a fast-tracked editorial in the International Journal of Infectious Diseases, written by Dr. Eskild Petersen and colleagues.

18 Jun 2015

Public health experts outline strategies for managing MERS-CoV outbreak

The ongoing outbreak in the Republic of Korea (South Korea) is an important reminder that the Middle East respiratory virus (MERS-CoV) requires constant vigilance and could spread to other countries including the United States. However, MERS can be brought under control with effective public health strategies, say two Georgetown University public health experts.

18 Jun 2015

New study launched in Liberia to better understand health consequences of Ebola virus disease

The Liberia-U.S. clinical research partnership known as PREVAIL has launched a study of people in Liberia who have survived Ebola virus disease (EVD) within the past two years. The study investigators hope to better understand the long-term health consequences of EVD, determine if survivors develop immunity that will protect them from future Ebola infection, and assess whether previously EVD-infected individuals can transmit infection to close contacts and sexual partners.

18 Jun 2015

University of Bristol researchers develop new technology to increase protection against bacterial infection

A new technology which could increase protection against antibacterial and antifungal infection for weeks, months or years has been developed by researchers at the University of Bristol.

18 Jun 2015

FDA accepts BiondVax's IND for Multimeric-001 vaccine

BiondVax Pharmaceuticals Ltd., a clinical stage biopharmaceutical company focused on developing and commercializing immunomodulation therapies for infectious diseases, today announced that its Investigational New Drug Application (IND) for its Multimeric-001 vaccine (M-001), has been accepted by the US Food and Drug Administration, and the Company was notified by its regulatory advisors that the 'study may proceed'.

17 Jun 2015

Study shows development assistance for health increased substantially since 1990

Funding for health in developing countries has increased substantially since 1990, with a focus on HIV/AIDS, maternal health, and newborn and child health, and limited funding for noncommunicable diseases, according to a study in the June 16 issue of JAMA.

17 Jun 2015

Completing sepsis resuscitation bundle in six hours after diagnosis

Blood poisoning, known as sepsis, is the most common cause of death in intensive care units, according to the National Institutes of Health. The body's immune response to fight the infection triggers inflammation that restricts blood flow and leads to multiple organ failure.

17 Jun 2015

Earthquake-ravaged Nepal faces 'very high' risk of hepatitis E outbreak

During the coming monsoon season, survivors of the recent earthquake that destroyed parts of Nepal face a "very high" risk of a hepatitis E outbreak that could be especially deadly to pregnant women, according to a consensus statement from a group of infectious disease experts from around the world.

17 Jun 2015

Regulatory T cells critical for the immune system's ability to fight off future pathogen attacks

Just as militaries need to have trained, experienced soldiers ready for future wars, making sure that the immune system has enough battle-ready T cells on hand is important for fast-acting, more effective vaccines, according to Penn State researchers.

17 Jun 2015

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

For decades, American travelers to international destinations have been plagued by acute gastrointestinal illnesses that can arise from travel to other countries. The Center for Disease Control warns that depending on the destination, between 30 to 70 percent of travelers can expect to experience gastrointestinal distress from ingesting foreign or pathogenic bacteria that can be present in poorly sanitized water or food.

17 Jun 2015

Disease/Infection News

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

New book examines all aspects of HBV and HDV infections

Analysis of transportation data could help predict spread of flu epidemic across the U.S.

Australian researchers launch global search to discover antibiotics against superbug bacteria

Three studies describe advances toward development of antibodies to stop HIV

Sequence of immunizations could be the promising route to HIV vaccine

Survey finds first evidence of MRSA in sausages, minced pork from supermarkets in the UK

New review highlights strategies to inhibit infections during the laundering process of HCT

Experimental AIDS vaccine candidate stimulates immune system to block infection in animal model

Scientists create new model to study latent HIV infection in brain cells

Key lessons from Middle East Respiratory Syndrome outbreak in South Korea

Public health experts outline strategies for managing MERS-CoV outbreak

New study launched in Liberia to better understand health consequences of Ebola virus disease

University of Bristol researchers develop new technology to increase protection against bacterial infection

FDA accepts BiondVax's IND for Multimeric-001 vaccine

Study shows development assistance for health increased substantially since 1990

Completing sepsis resuscitation bundle in six hours after diagnosis

Earthquake-ravaged Nepal faces 'very high' risk of hepatitis E outbreak

Regulatory T cells critical for the immune system's ability to fight off future pathogen attacks

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

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