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Clinical trial suggests HIV patients should start therapy sooner rather than later

Findings from a large-scale clinical trial have shown that people with HIV should start antiretroviral therapy as soon as they have been diagnosed, irrespective of what their CD4+ count is...

28 May 2015

Research findings could help guide development of potential treatments for HCV

Warring armies use a variety of tactics as they struggle to gain the upper hand. Among their tricks is to attack with a decoy force that occupies the defenders while an unseen force launches a separate attack that the defenders fail to notice.

28 May 2015

Earlier antiretroviral treatment benefits HIV-infected individuals

A major international randomized clinical trial has found that HIV-infected individuals have a considerably lower risk of developing AIDS or other serious illnesses if they start taking antiretroviral drugs sooner, when their CD4+ T-cell count--a key measure of immune system health--is higher, instead of waiting until the CD4+ cell count drops to lower levels. Together with data from previous studies showing that antiretroviral treatment reduced the risk of HIV transmission to uninfected sexual partners, these findings support offering treatment to everyone with HIV.

28 May 2015

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Actavis plc, a leading global specialty pharmaceutical company committed to infectious disease treatment innovation, today announced the creation of SHARE ID (Sharing Hospital data to Advance Research and Enhance patient care in Infectious Diseases), a collaborative program to leverage real-world data to advance the delivery and effectiveness of care for patients with serious infections due to antibiotic-resistant pathogens.

27 May 2015

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

Borrelidin is a naturally occurring antibiotic isolated from the Streptomyces species and initially from Streptomyces rochei in 1949. It is called Borrelidin because it was firstly discovered as having anti-Borrelia activity. Borrelia is a type of bacteria...

27 May 2015

New tool could help identify pathogens in food and beverages

Researchers at the National Polytechnic Institute (IPN) in Mexico, developed a technology capable of identifying pathogens in food and beverages. This technique could work in the restaurant industry as a biosensor to detect in what conditions food is before being eaten in order to avoid possible gastrointestinal diseases.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

AbbVie presented new results from the Phase 3 GIFT-I study of its investigational, all-oral, interferon (IFN)- and ribavirin (RBV)-free, two direct-acting antiviral treatment with ombitasvir/paritaprevir/ritonavir at the Annual Meeting of the Japan Society of Hepatology in Kumamoto, Japan.

27 May 2015

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion, and are a "serious and growing issue." Each year two million people in the U.S. contract antibiotic-resistant infections, and at least 23,000 people die as a direct result.

27 May 2015

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

The team has completed two genomics studies on the tropical disease, a condition that is estimated to cause up to 30 million illnesses and over a quarter of a million deaths globally each year.

27 May 2015

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

By unlocking the secrets of a bizarre virus that survives in nearly boiling acid, scientists at the University of Virginia School of Medicine have found a blueprint for battling human disease using DNA clad in near-indestructible armor.

27 May 2015

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

A new study has demonstrated that a protein called Niemann-Pick C1 (NPC1) is critical for the Ebola virus to infect a host. The study, published in the May/June issue of mBio, the online open-access journal of the American Society for Microbiology, suggests that drugs that block NPC1 could be used to treat this deadly disease.

27 May 2015

Researchers make important breakthrough in identifying major drivers of excessive coughing

Cough treatments could change dramatically after the herpes virus helped researchers discover that the respiratory tract links to two different parts of the nervous system.

27 May 2015

South Asian Health Foundation wins BMJ “Diabetes team of the year” award

The South Asian Health Foundation (SAHF) has been named ‘Diabetes Team of the Year’ at the prestigious 2015 BMJ Awards...

26 May 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

Researchers create new vaccine development method for H5N1, H7N9 strains of avian influenza

A recent study with Kansas State University researchers details vaccine development for two new strains of avian influenza that can be transmitted from poultry to humans. The strains have led to the culling of millions of commercial chickens and turkeys as well as the death of hundreds of people.

24 May 2015

Breakthrough in fight against rare kidney disease - Membranous Nephropathy

Scientists at The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have made a significant breakthrough in the fight against Membranous Nephropathy (MN) - a rare kidney disease which can lead to kidney failure.

22 May 2015

Lafora rare disease could be aggravated by oxidative stress

Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora rare disease could be aggravated by oxidative stress.

22 May 2015

Sex-determining gene in mosquitoes may help reduce disease transmission

Researchers with the Fralin Life Science Institute at Virginia Tech have identified a gene responsible for sex determination in mosquitoes that can transmit yellow fever, dengue, and chikungunya viruses.

22 May 2015

GHIT Fund expands investments in leishmaniasis, diagnostic tests

The Global Health Innovative Technology Fund, which in the last two years has funded almost $32 million for innovative tools to tackle global infectious diseases, today announced additional investments of nearly $11 million that bring its portfolio to approximately $43 million.

22 May 2015

Disease/Infection News

Clinical trial suggests HIV patients should start therapy sooner rather than later

Research findings could help guide development of potential treatments for HCV

Earlier antiretroviral treatment benefits HIV-infected individuals

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

New tool could help identify pathogens in food and beverages

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

Researchers make important breakthrough in identifying major drivers of excessive coughing

South Asian Health Foundation wins BMJ “Diabetes team of the year” award

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Researchers create new vaccine development method for H5N1, H7N9 strains of avian influenza

Breakthrough in fight against rare kidney disease - Membranous Nephropathy

Lafora rare disease could be aggravated by oxidative stress

Sex-determining gene in mosquitoes may help reduce disease transmission

GHIT Fund expands investments in leishmaniasis, diagnostic tests

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