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Anacor Pharmaceuticals submits tavaborole NDA to FDA for treatment of onychomycosis

Anacor Pharmaceuticals announced today that on July 26, 2013 it submitted its New Drug Application to the U.S. Food and Drug Administration for tavaborole, its drug candidate for the topical treatment of onychomycosis. Onychomycosis is a fungal infection of the nail and nail bed that affects approximately 35 million people in the United States.

30 Jul 2013

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

The USPSTF agreed with the CDC that since most patients (75%) who are currently infected with hepatitis C were born between 1945 - 1965, and since risk-based screening has not been successful in identifying these individuals, that a one time age-based hepatitis C blood test was necessary.

29 Jul 2013

Saudi and UK scientists provide detailed picture of MERS coronavirus

Saudi and UK scientists provide the most detailed picture yet of the clinical and laboratory characteristics of Middle East Respiratory Syndrome (MERS) coronavirus, revealing a wide range of clinical symptoms and an extremely high death rate among patients with co-existing medical conditions.

29 Jul 2013

World Hepatitis Alliance calls for urgent action to address viral hepatitis

On World Hepatitis Day, the World Hepatitis Alliance has called for urgent attention to be given to recent figures showing that although viral hepatitis kills as many as HIV/AIDS, the great majority of countries have no programmes in place to tackle it.

29 Jul 2013

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

Researchers have generated functional hepatocytes from human stem cells, transplanted them into mice with acute liver injury, and shown the ability of these stem-cell derived human liver cells to function normally and increase survival of the treated animals.

29 Jul 2013

CHMP gives positive opinion for approval of once-daily QVA149 for treatment of COPD

Sosei Group Corporation confirms the information released by Novartis that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion for approval of once-daily Ultibro® Breezhaler®, as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD).

29 Jul 2013

GlaxoSmithKline receives CHMP positive opinion for REVOLADE

Ligand Pharmaceuticals Incorporated partner GlaxoSmithKline announced that today, the European Medicines Agency's Committee for Medicinal Products for Human Use issued a positive opinion recommending marketing authorization for GSK's REVOLADE (eltrombopag) as a treatment for low platelet counts (thrombocytopenia) in adult patients with chronic hepatitis C infection, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy

26 Jul 2013

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Reporters Peter Whoriskey and Dan Keating have opened Post readers' eyes to the fact that Medicare pays for physician services - a $69.6 billion item in 2012 - according to an arcane and little-known price list, over which doctors themselves exercise considerable and less-than-totally-transparent influence (7/24).

26 Jul 2013

WHO issues travel advice on MERS-CoV for pilgrims traveling to Kingdom of Saudi Arabia

The World Health Organization has issued interim travel advice on the Middle East respiratory syndrome coronavirus (MERS-CoV), which has affected nine countries to date.

26 Jul 2013

New species of adenovirus can spread from monkey to human, say researchers

Adenoviruses commonly infect humans, causing colds, flu-like symptoms and sometimes even death, but now UC San Francisco researchers have discovered that a new species of adenovirus can spread from primate to primate, and potentially from monkey to human.

26 Jul 2013

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

A Miriam Hospital researcher has joined forces with international colleagues to call for new strategies to better manage and improve assessment and treatment for hepatitis C (HCV) infection in individuals who inject drugs.

26 Jul 2013

Zydus, IDRI partner to develop visceral leishmaniasis vaccine candidate

In a unique partnership, Zydus, India's fourth largest healthcare group and an innovation-led global healthcare provider, and IDRI, a Seattle-based non-profit research and product development organization, announced today they are collaborating on the production and clinical development of IDRI's visceral leishmaniasis vaccine candidate, designed to prevent the deadly parasitic disease.

26 Jul 2013

FDA allows marketing of Xpert MTB/RIF Assay for treatment of TB

The U.S. Food and Drug Administration today allowed marketing of the Xpert MTB/RIF Assay, the first FDA-reviewed test that can simultaneously detect bacteria that cause tuberculosis and determine if the bacteria contain genetic markers that makes them resistant to rifampin, an important antibiotic for the treatment of TB.

26 Jul 2013

First lots of 2013-2014 seasonal influenza vaccine released for U.S. distribution

Sanofi Pasteur, the vaccines division of Sanofi, announced today that the first lots of Fluzone (Influenza Virus Vaccine) for the 2013-2014 season have been released by the U.S. Food and Drug Administration for U.S. distribution and were shipped July 24.

25 Jul 2013

Report shows 2824 new cases of hantavirus disease in Germany in 2012

2824 new cases of hantavirus disease were reported in Germany in 2012, the highest number ever in a single year. In the current issue of Deutsches -rzteblatt International, Detlev Kr-ger and coauthors present the main facts about this disease (Dtsch Arztebl Int 2013; 110[27-28]: 461-7).

25 Jul 2013

Forced-air patient warming systems may affect airflows in OR; increase exposure to airborne contaminants

Forced-air systems used to keep patients warm during surgery may affect the performance of operating room (OR) ventilation systems-potentially increasing exposure to airborne contaminants, reports a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Jul 2013

Discovery of pressure-driven infection mechanism opens door to new treatments for viral infections

The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting in a new study.

25 Jul 2013

Combination treatment can reduce hepatitis C infection in people who inject drugs

The burden of liver disease could be dramatically reduced by scaling up the combination of interventions for hepatitis C infection among people who inject drugs according to University of Bristol researchers. The findings, published today [24 July], form part of new global recommendations on treating the virus.

25 Jul 2013

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) provide the first proof of concept data showing that a monoclonal antibody can neutralize human norovirus. This research, which could one day lead to effective therapies against the virus, was published online ahead of print in the Journal of Virology.

25 Jul 2013

Combination of 6 comprehensive measures to prevent spread of hepatitis C

UC San Francisco researchers are recommending a combination of six comprehensive measures to prevent the spread of hepatitis C, in an effort to address the more than 31,000 young people they estimate may be newly infected with the virus each year in the United States due to injection-drug use.

25 Jul 2013

Disease/Infection News

Anacor Pharmaceuticals submits tavaborole NDA to FDA for treatment of onychomycosis

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

Saudi and UK scientists provide detailed picture of MERS coronavirus

World Hepatitis Alliance calls for urgent action to address viral hepatitis

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

CHMP gives positive opinion for approval of once-daily QVA149 for treatment of COPD

GlaxoSmithKline receives CHMP positive opinion for REVOLADE

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

WHO issues travel advice on MERS-CoV for pilgrims traveling to Kingdom of Saudi Arabia

New species of adenovirus can spread from monkey to human, say researchers

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

Zydus, IDRI partner to develop visceral leishmaniasis vaccine candidate

FDA allows marketing of Xpert MTB/RIF Assay for treatment of TB

First lots of 2013-2014 seasonal influenza vaccine released for U.S. distribution

Report shows 2824 new cases of hantavirus disease in Germany in 2012

Forced-air patient warming systems may affect airflows in OR; increase exposure to airborne contaminants

Discovery of pressure-driven infection mechanism opens door to new treatments for viral infections

Combination treatment can reduce hepatitis C infection in people who inject drugs

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Combination of 6 comprehensive measures to prevent spread of hepatitis C

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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