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Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Sanford-Burnham Medical Research Institute and 60- Pharmaceuticals, LLC, have entered into a partnership to test furin, a human proteinase, as a drug target for the treatment of dengue fever, one of the most common infectious diseases in the tropics and subtropics.

5 Mar 2013

Editorial, opinion piece address efforts to eradicate polio

The Independent recently published an editorial and opinion piece discussing the global effort to eradicate polio.

5 Mar 2013

Examining NTD response in Obama's second term

"As President Obama's second term begins to take shape and new faces assume new leadership roles, many in Washington are trying to gauge what will happen to global health," Michelle Brooks, policy director at the Global Network for Neglected Tropical Diseases (NTDs), writes in the organization's "End the Neglect" blog.

5 Mar 2013

Study finds antiretroviral-based strategies to prevent HIV infection among women prove ineffective

Three antiretroviral-based strategies intended to prevent HIV infection among women did not prove effective in a major clinical trial in Africa.

5 Mar 2013

Results of two important studies published in March issue of AIDS

The results of two important studies have been published in the March issue of AIDS, the official journal of the International AIDS Society. One study notes that screening for HIV should be performed more frequently—up to every three months for the highest-risk patients, while low-risk groups to be tested every three years. A second study demonstrates a link between heavy drinking and risky behaviors for men who have sex with men (MSM).

5 Mar 2013

Carbohydrate-rich diet during pregnancy may predict RSV severity in infants

An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy, according to a Vanderbilt study published in the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2013

World Trade Organization meeting this week to discuss proposed extension of TRIPS transition period for LDCs

"On March 5-6, the Trade-Related Aspects of Intellectual Property Rights Council of the World Trade Organization will meet in Geneva to seal the fate of the proposal lengthening the TRIPS transition period for the 49 least-developed countries [LDCs]," Devex's "The Development Newswire" reports, noting, "The transition period, set to expire July 2013, exempts LDCs from the terms of the TRIPS agreement on patents and test data protection for pharmaceuticals."

5 Mar 2013

Study highlights long-term benefits of early antiretroviral therapy initiated in infants

A study led by University of Massachusetts Medical School professor and immunologist Katherine Luzuriaga, MD, and Johns Hopkins Children's Center virologist Deborah Persaud, MD, highlights the long-term benefits of early antiretroviral therapy (ART) initiated in infants.

5 Mar 2013

New tool can accurately forecast malaria epidemics in northwestern India

Sea surface temperatures in the tropical South Atlantic Ocean can be used to accurately forecast, by up to four months, malaria epidemics thousands of miles away in northwestern India, a University of Michigan theoretical ecologist and her colleagues have found.

5 Mar 2013

UAE Exchange Shamshabad branch actively participated in Pulse Polio immunization program

"Children's Health, The Nation's Wealth" is the motto that all the staff of UAE Exchange Shamshabad branch held close to their heart. The second phase of the Pulse Polio Immunization program, was held across India on February 24th.

5 Mar 2013

Overall risk of infection associated with most neuroangiographic procedures is very low

Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infection-even without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

5 Mar 2013

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Interim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).

5 Mar 2013

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

HIV infection may increase risk of acute myocardial infarction

A study that analyzed data from more than 82,000 veterans suggests that infection with the human immunodeficiency virus (HIV) was associated with an increased risk of acute myocardial infarction (AMI, heart attack) beyond what is explained by recognized risk factors, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

4 Mar 2013

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

A team of researchers from Johns Hopkins Children's Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School describe the first case of a so-called "functional cure" in an HIV-infected infant. The finding, the investigators say, may help pave the way to eliminating HIV infection in children.

4 Mar 2013

Community-led engagement, greater access needed to end polio

"While the challenges we face in the last polio reservoirs are difficult, they are not intractable," Bekele Geleta, secretary general of the International Federation of the Red Cross and Red Crescent Societies, writes in an AlertNet opinion piece.

2 Mar 2013

NPR blog examines debate over option B+ HIV prevention strategy

NPR's "Shots" blog examines the debate over Option B+, a strategy to prevent mother-to-child HIV transmission that "aims to put every pregnant woman with HIV on triple-drug treatment and keep her on it for the rest of her life -- even if the virus has not yet damaged her immune system to the point where she needs medications to preserve her own health."

2 Mar 2013

Significant link between defective viruses and increased rate of transmission of major disease

Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new research by UCLA life scientists indicates.

2 Mar 2013

Sustained funding necessary for success of global polio eradication plan

"We are teaming up to tackle one of the most ambitious public health goals ever set: eradicating polio, a disease that has haunted humanity at least since ancient Egypt," New York City Mayor Michael Bloomberg, founder of Bloomberg L.P., and Bill Gates, chair of Microsoft and co-chair of the Bill & Melinda Gates Foundation, write in a Wall Street Journal opinion piece.

2 Mar 2013

Measles epidemic affecting tens of thousands of children in DRC, MSF warns

"A measles epidemic has affected tens of thousands of children in northern Democratic Republic of Congo (DRC), overwhelming health facilities, says medical charity Médecins Sans Frontières (MSF)," IRIN reports.

2 Mar 2013

Disease/Infection News

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Editorial, opinion piece address efforts to eradicate polio

Examining NTD response in Obama's second term

Study finds antiretroviral-based strategies to prevent HIV infection among women prove ineffective

Results of two important studies published in March issue of AIDS

Carbohydrate-rich diet during pregnancy may predict RSV severity in infants

World Trade Organization meeting this week to discuss proposed extension of TRIPS transition period for LDCs

Study highlights long-term benefits of early antiretroviral therapy initiated in infants

New tool can accurately forecast malaria epidemics in northwestern India

UAE Exchange Shamshabad branch actively participated in Pulse Polio immunization program

Overall risk of infection associated with most neuroangiographic procedures is very low

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

HIV infection may increase risk of acute myocardial infarction

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

Community-led engagement, greater access needed to end polio

NPR blog examines debate over option B+ HIV prevention strategy

Significant link between defective viruses and increased rate of transmission of major disease

Sustained funding necessary for success of global polio eradication plan

Measles epidemic affecting tens of thousands of children in DRC, MSF warns

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

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