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NQF endorses two surgical outcomes-based measures from ACS NSQIP

Two outcomes-based measures from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) were recently endorsed by the National Quality Forum.

7 Feb 2012

Forum for Collaborative HIV Research suggests new approach for conducting Phase 3 HIV clinical trials

As the war on HIV/AIDS begins its fourth decade, medical researchers, pharmaceutical manufacturers, patient advocates and government regulators face a new and unexpected scientific challenge: how to demonstrate the safety and efficacy of promising new antiretroviral drugs when the two traditional study designs – the superiority trial and the non-inferiority trial – are no longer useful in showing improvements in both "treatment experienced" patients and those who have never received drug therapy (treatment-naive patients).

7 Feb 2012

FDA approves ivermectin lotion for treatment of head lice

Sanofi announced today that the U.S. Food and Drug Administration (FDA) has approved Sklice® (ivermectin) lotion, 0.5% for the topical treatment of head lice, in patients 6 months of age and older. Effective and well-tolerated, Sklice Lotion treats lice in most patients with a single 10-minute application of the lotion, without nit combing.

7 Feb 2012

National Black HIV/AIDS Day brings new statistics

According to statistics from the Centers for Disease Control (CDC), Blacks represent approximately 14 percent of the U.S. population, but accounted for an estimated 44 percent of new HIV infections in 2009. Over the same period, the rate of new HIV infections among black women was 15 times that of White women, and over 3 times the rate of Hispanic/Latina women.

7 Feb 2012

Antiretroviral therapy does not increase severity of psychiatric disorders

A study of more than 300 children and adolescents with human immunodeficiency virus (HIV) revealed no association between specific antiretroviral therapy and the severity of psychiatric disorders.

7 Feb 2012

Proactive test-and-treat case-detection strategy can combat malaria

As researchers work to eliminate malaria worldwide, new strategies are needed to find and treat individuals who have malaria, but show no signs of the disease. The prevalence of asymptomatic or minimally symptomatic malaria can be as high as 35 percent in populations with malaria and these asymptomatic individuals can serve as a reservoir for spreading malaria even in areas where disease transmission has declined.

7 Feb 2012

U.N. supporting yellow fever vaccination campaigns in Cameroon, Ghana

Following an outbreak of the mosquito-borne yellow fever virus in Cameroon that has infected at least 23 people and killed at least seven people, U.N. and local officials are working to vaccinate "1.2 million people considered at high risk of contracting yellow fever, which has no cure," the U.N. News Centre reports.

7 Feb 2012

LE strips can rapidly diagnose periprosthetic joint infection

Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows leukocyte esterase reagent (LE) strips, common in diagnosing urinary tract infections, can also have a role in rapid diagnosis of PJI.

7 Feb 2012

Closing the 'cancer divide' between developing and developed countries

Noting "there is a huge 'cancer divide' between rich and poor," with more than half of new cancer cases and almost two-thirds of all cancer deaths occurring in developing countries, this year's World Cancer Day theme, "Together It Is Possible," "calls on all individuals, organizations and governments to do their part to reduce premature deaths from cancers by 25 percent by 2025," Felicia Knaul, secretariat for the Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries, and Jonathan Quick, president of Management Sciences for Health, write in a Huffington Post opinion piece.

7 Feb 2012

WHO disputes study's claims that global malaria deaths are double current estimates

The WHO has disputed a study published last week in the Lancet "that claims nearly twice as many people are dying of malaria than current estimates," VOA News reports.

7 Feb 2012

Supporting scientific evidence under PEPFAR to end AIDS

On Wednesday, several HIV experts spoke at a Capitol Hill briefing "supporting the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program's reliance on scientific evidence to drive its work to end AIDS," the Center for Global Health Policy's "Science Speaks" blog reports.

7 Feb 2012

Dispute over malaria figures highlights lack of certainty in data in age of 'information overload'

In this post in TIME World's "Global Spin" blog, TIME's Africa bureau chief Alex Perry examines questions surrounding an Institute for Health Metrics and Evaluation (IHME) study published in the Lancet on Friday that suggests "malaria kills almost twice as many people a year as previously believed."

7 Feb 2012

Economic transformation in Latin America an opportunity to improve NTD strategies, DNDi regional director says

"The rise of emerging economies in Latin America is an opportunity to improve strategies for fighting neglected illnesses and increase the region's contribution to the global struggle against them, says" Eric Stobbaerts, the Latin America director of the independent Drugs for Neglected Diseases initiative (DNDi), Inter Press Service reports.

7 Feb 2012

Closing elementary and secondary schools can help slow pH1N1 transmission

Closing elementary and secondary schools can help slow the spread of infectious disease and should be considered as a control measure during pandemic outbreaks, according to a McMaster University led study.

7 Feb 2012

Whole-genome sequencing helps trace the path of European E. coli outbreak

Using whole-genome sequencing, a team led by researchers from Harvard School of Public Health (HSPH) and the Broad Institute has traced the path of the E. coli outbreak that sickened thousands and killed over 50 people in Germany in summer 2011 and also caused a smaller outbreak in France.

7 Feb 2012

Positive data from Chimerix CMX001 Phase 2 study on CMV disease

Chimerix, Inc., a biotechnology company developing novel antiviral therapeutics, today announced positive results from CMX001 Study 201, a Phase 2 study evaluating CMX001 for the prevention of cytomegalovirus (CMV) disease in hematopoietic stem cell transplant (HCT) recipients.

6 Feb 2012

Asian bird flu update for Ferbruary 2012

Health workers in Nepal are to cull thousands of chickens following the discovery of the H5N1 strain of bird flu in the southeastern part of the Himalayan country.

6 Feb 2012

Panel discussion shows heated controversy over H5N1 research

"The controversy over research about potentially dangerous H5N1 viruses heated up [Thursday night] in a New York City debate that featured some of the leading voices exchanging blunt comments on the alleged risks and benefits of publishing or withholding the full details of the studies," CIDRAP News reports.

6 Feb 2012

GSK voluntarily pauses enrollment in GSK2251052 clinical trials for cUTI

Anacor Pharmaceuticals announced today that its partner GlaxoSmithKline has voluntarily paused enrollment in its current clinical trials of GSK2251052 due to a recently identified microbiological finding in a small number of patients in the Phase 2b trial of GSK '052 for the treatment of complicated urinary tract infections (cUTI).

6 Feb 2012

BioLineRx, Genoscience and RFS Pharma enter agreement for BL-8030 Hepatitis C treatment

BioLineRx, a biopharmaceutical development company, announced today it has signed a worldwide, exclusive license agreement with Genoscience and RFS Pharma to develop and commercialize BL-8030, an orally available treatment for Hepatitis C.

6 Feb 2012