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Results from Presidio’s PPI-668 Phase 1a-1b trial on chronic HCV

Presidio Pharmaceuticals, Inc. announced results today from a Phase 1a-1b clinical trial of PPI-668, a potent, pan-genotypic HCV NS5A inhibitor being developed for the treatment of patients with chronic hepatitis C.

19 Apr 2012

Scientists identify hypervirulent Salmonella bacteria

UC Santa Barbara researchers have discovered Salmonella bacteria that are up to 100 times more capable of causing disease. Their findings may help prevent food poisoning outbreaks that continue to plague public health and the food industry.

19 Apr 2012

Oral bacteria may cause problems in arthritis patients

The culprit behind a failed hip or knee replacements might be found in the mouth. DNA testing of bacteria from the fluid that lubricates hip and knee joints had bacteria with the same DNA as the plaque from patients with gum disease and in need of a joint replacement.

19 Apr 2012

Anti-HIV pill could prevent thousands of new infections: Study finds

A once daily pill to prevent HIV infection could significantly reduce the spread of the AIDS-causing virus. However it would only be cost-effective if limited to men at very high risk for HIV infection, according to a new study.

18 Apr 2012

Comparing publicly available hospital readmission rates can lead to misinformation

The odds that someone undergoing spinal surgery at a particular hospital will have to be readmitted to the same hospital within 30 days is an important measure of the quality of care patients receive. That's because these "hospital readmission rates" often reflect problems like hospital-acquired infections or complications from surgery.

18 Apr 2012

Strengthening collective voice, influence of biomedical researchers in global health field

In this post in the Global Network for Neglected Tropical Diseases' "End the Neglect" blog, guest blogger Jessica Taaffe, founder of Scientists for Global Health (SciGlo) and a postdoctoral fellow researching severe malaria immunopathogenesis at the National Institute of Allergy and Infectious Diseases, "discusses the importance of the biomedical community's contributions to improving health worldwide,"

18 Apr 2012

New PBC tool for prioritizing laboratory-based CD-4 cell count testing

One of the major problems that has slowed progress toward universal access to life-saving antiretroviral therapy (ART) to treat AIDS in developing nations has been limited availability of laboratories and trained medical staff to conduct blood tests of immune system CD-4 T-cell levels that indicate when to start ART.

18 Apr 2012

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

A team of scientists from the University of Missouri created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth disease, an inherited neuromuscular disease affecting approximately 150,000 people in the United States.

18 Apr 2012

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.

18 Apr 2012

Voluntary testing, counseling for HIV decreases unprotected sex acts among cocaine, heroin users

Voluntary testing and counseling (VT/C) for HIV or sexually transmitted infections (STI) among cocaine and heroin users who were treated in the emergency department (ED), accompanied by referral to drug treatment, was associated with reduction in unprotected sex acts and fewer sex acts while high according to researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC).

18 Apr 2012

Study sheds light on why ageing makes us more susceptible to gum disease

New research from Queen Mary, University of London in collaboration with research groups in the USA sheds light on why gum disease can become more common with old age.

18 Apr 2012

No added HIV risk with hormonal contraceptives

An HIV prevention trial that pre-dates the shift to antiretroviral (ARV)-based approaches is nonetheless helping to answer some of the most relevant and topical questions the field is facing today.

18 Apr 2012

Flu outbreak at veterans home

State Veterans' Affairs Commissioner Linda Schwartz told The Associated Press that the veterans were taken to Hartford Hospital after a number began complaining of flu-like symptoms. The 18 men live at the Connecticut State Veterans Home in either the Sgt. John L. Levitow Veteran's Health Center or a residential facility.

17 Apr 2012

Responses to U.S. nomination of Jim Kim for World Bank presidency

The following is a summary of several recent pieces published in response to the U.S. nomination of Jim Yong Kim to be the next president of the World Bank.

17 Apr 2012

ACS, CDC partner to improve surgical patient safety

A joint, strategic partnership to improve surgical patient safety at the national level was announced today by leaders of the American College of Surgeons (ACS) and the Centers for Disease Control and Prevention.

17 Apr 2012

Genetically modified mosquitoes offer hope of malaria eradication amid growing drug resistance

"In recent weeks, the emergence on the Thai-Myanmar border of malaria strains resistant to artemisinin, a plant-derived drug, have led to pessimistic headlines and reminders of the setback caused by resistance to the drug chloroquine, which began in the 1950s," columnist and author Matt Ridley writes in the Wall Street Journal's "Mind & Matter," noting, "April 25 is World Malaria Day, designed to draw attention to the planet's biggest infectious killer."

17 Apr 2012

Use of sewage-contaminated water to irrigate crops poses disease risk in Zimbabwe, IRIN reports

IRIN examines how local Zimbabwean farmers' usage of water containing raw sewage to irrigate their crops poses a risk of disease transmission to people who consume the vegetables.

17 Apr 2012

International Microbicides Conference to discuss state of HIV prevention research

Researchers, activists and funders are meeting this week in Sydney to discuss the state of HIV prevention research. The biennial International Microbicides Conference, which was opened on Sunday evening by the Honorable Tanya Plibersek MP, Australian Minster of Health, is taking place amid renewed optimism about development and delivery of new HIV prevention options with the potential for ending the AIDS epidemic, including anti-retroviral based microbicides and pre-exposure prophylaxis.

17 Apr 2012

FDA grants 510(k) clearance for QIAGEN’s molecular detection PCR technology

QIAGEN N.V. today announced that the U.S. Food and Drug Administration (FDA) has granted two 510(k) clearances for its real-time PCR (polymerase chain reaction) instrument Rotor-Gene Q MDx and a compatible test for the detection of Influenza A/B, the artus Infl A/B RG RT-PCR Kit, for in vitro diagnostic use.

From QIAGEN Manchester Limited 17 Apr 2012

Canadian docs recommend HPV vaccine for boys

Girls have had access to free HPV vaccinations for five years - administered to protect them against cervical cancer - and this week, the Canadian Cancer Advocacy Coalition called on provincial governments to pay for the vaccine for boys as well. In January, the National Advisory Committee on Immunization recommended HPV vaccination for males aged nine to 25.

16 Apr 2012