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Soligenix reports results from long-term stability studies of SGX204 anthrax vaccine

Soligenix, Inc., a development stage biopharmaceutical company, announced today results from long-term stability studies of its proprietary DNI anthrax rPA subunit protein vaccine, known as SGX204.

19 Jan 2012

Gilead Sciences receives FDA approval for Viread to treat pediatric HIV infection

Gilead Sciences, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Viread in combination with other antiretroviral agents for the treatment of HIV-1 infection in pediatric patients ages 2-12.

19 Jan 2012

Scientists crack genetic code for Schistosoma haematobium

Scientists have cracked the genetic code and predicted some high priority drug targets for the blood parasite Schistosoma haematobium, which is linked to bladder cancer and HIV/ AIDS and causes the insidious urogenital disease schistosomiasis haematobia in more than 112 million people in Africa.

19 Jan 2012

Bristol-Myers Squibb agrees purchase of Inhibitex for $2.5Bn

American pharmaceutical giant Bristol-Myers Squibb has agreed the purchase of US biotech company Inhibitex, in a $2.5Bn (£1.6bn) deal which includes the promising new anti-hepatitis C drug INX-189, first designed and prepared in Cardiff University.

19 Jan 2012

TB associated with EGFR mutations in patients with lung adenocarcinoma

Tuberculosis (TB) has been suspected to increase a person's risk of lung cancer because the pulmonary inflammation and fibrosis can induce genetic damage. However, direct evidence of specific genetic changes and the disease have not been extensively reported.

19 Jan 2012

Alpha-hemolysin may play an unexpected role in UTIs

Researchers from the University of Utah have identified a process by which the most common types of urinary tract infection-causing bacteria are able to trigger bladder cell shedding and disable immune responses. According to this new study, published in the Jan. 19, 2012, issue of Cell Host & Microbe, α-hemolysin, a toxin secreted by many strains of Escherichia coli (E. coli), may play an important, unexpected role during both the establishment and persistence of urinary tract infections.

19 Jan 2012

Counterfeit malaria drugs endanger millions of lives

According to researchers fake and poor quality anti-malarial drugs are threatening efforts to control the disease in Africa and could put millions of lives at risk. These counterfeit medicines could harm patients and promote drug resistance among malaria parasites, warns the study, funded by the Wellcome Trust.

18 Jan 2012

Indian, WHO officials to meet to discuss managing cases of highly drug-resistant TB

Health officials from India and the WHO are scheduled to meet in Mumbai on Tuesday to discuss how to manage the cases of at least 12 patients infected with a highly drug-resistant tuberculosis (TB) strain, Bloomberg reports (Narayan, 1/17).

18 Jan 2012

Global Fund executive director urges Ukraine to step up efforts to fight HIV/AIDS

Michel Kazatchkine, executive director of the Global Fund to Fight AIDS, Tuberculosis and Malaria, on Monday "urged Ukraine to step up its efforts to fight the HIV/AIDS epidemic," calling "on the Ukrainian authorities to expand opiate substitution therapy, ensure HIV/AIDS treatment in prison and increase government funding of anti-AIDS programs," the Associated Press reports.

18 Jan 2012

WHO to take lead role in addressing controversial bird flu research, official says

"The World Health Organization says it will take a role in helping sort through an international scientific controversy over two bird flu studies that the U.S. government deemed too dangerous to publish in full," the Canadian Press/Winnipeg Free Press reports.

18 Jan 2012

Researchers to anticipate and track risk for infectious disease outbreak at London Olympics

A research team led by St. Michael's Hospital's Dr. Kamran Khan is teaming up with British authorities to anticipate and track the risk for an infectious disease outbreak at the London Olympics this summer.

18 Jan 2012

Paragon receives JVAP-CBMS contract from DoD

Paragon Bioservices, Inc., a Baltimore-based CMO focused on the process development and manufacturing of biologics, announced today that it has been awarded a JVAP-CBMS contract from the Department of Defense (DoD) for the vaccine development and subsequent GMP manufacturing of the "VEE Replicon Particle Trivalent Filovirus Vaccine."

18 Jan 2012

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided.

18 Jan 2012

WHO's Chan urges new approach to preventing, fighting diseases at Executive Board meeting

"Countries need to change their current mindset to successfully tackle non-communicable diseases (NCDs), the head of the United Nations World Health Organization (WHO) said Monday, adding that governments will need to explore new approaches to prevent and treat these diseases, which have quickly become one of the most pressing issues in public health," the U.N. News Centre reports.

18 Jan 2012

India applauded for marking one year without polio, but urged to also focus on other diseases

In this post in the Center for Global Development's (CGD) "Global Health Policy" blog, Victoria Fan, a research fellow at CGD, and Rachel Silverman, a research assistant at the center, respond to India's marking of one-year since a case of polio was found in the country, writing, "While we applaud India for its commitment to reaching this milestone, let us not allow this recent success obscure the sorry state of vaccination in India."

18 Jan 2012

Ivera receives new FDA clearance for Curos disinfecting port protector

Ivera Medical Corporation today announced it has received a new FDA 510(k) clearance for its Curos disinfecting port protector which reflects the company's ongoing determination to continuously improve its products to better deliver solutions designed to reduce hospital-acquired catheter related bloodstream infections.

18 Jan 2012

U.S. to provide nearly $1B over five years to Bangladesh for poverty, health, agriculture programs

A U.S. Embassy statement on Saturday said the U.S. would provide nearly $1 billion to Bangladesh over the next five years "towards alleviating poverty and malnutrition, as well as family planning and the fight against infectious diseases," Reuters reports.

18 Jan 2012

Counterfeit, substandard drugs threaten progress in controlling malaria in Africa, researchers report

"Hopes of controlling malaria in Africa could be wrecked by criminals who are circulating counterfeit and substandard drugs, threatening millions of lives, scientists" said in a study published in the Malaria Journal last month, the Guardian reports.

18 Jan 2012

Afghan President Karzai urges Taliban to allow polio vaccination teams into insurgent-controlled areas

Afghanistan President Hamid Karzai on Tuesday "urged the Taliban to allow teams conducting a polio vaccination campaign access to areas under their control" and "said that whoever hampers the medical workers 'is the enemy of our children's future,'" the Associated Press/Washington Post reports.

18 Jan 2012

Researchers develop simple process for synthesis of artemisinin

The most effective anti-malaria drug can now be produced inexpensively and in large quantities. This means that it will be possible to provide medication for the 225 million malaria patients in developing countries at an affordable price. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universit-t Berlin have developed a very simple process for the synthesis of artemisinin, the active ingredient that pharmaceutical companies could only obtain from plants up to now.

18 Jan 2012

Disease/Infection News

Soligenix reports results from long-term stability studies of SGX204 anthrax vaccine

Gilead Sciences receives FDA approval for Viread to treat pediatric HIV infection

Scientists crack genetic code for Schistosoma haematobium

Bristol-Myers Squibb agrees purchase of Inhibitex for $2.5Bn

TB associated with EGFR mutations in patients with lung adenocarcinoma

Alpha-hemolysin may play an unexpected role in UTIs

Counterfeit malaria drugs endanger millions of lives

Indian, WHO officials to meet to discuss managing cases of highly drug-resistant TB

Global Fund executive director urges Ukraine to step up efforts to fight HIV/AIDS

WHO to take lead role in addressing controversial bird flu research, official says

Researchers to anticipate and track risk for infectious disease outbreak at London Olympics

Paragon receives JVAP-CBMS contract from DoD

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

WHO's Chan urges new approach to preventing, fighting diseases at Executive Board meeting

India applauded for marking one year without polio, but urged to also focus on other diseases

Ivera receives new FDA clearance for Curos disinfecting port protector

U.S. to provide nearly $1B over five years to Bangladesh for poverty, health, agriculture programs

Counterfeit, substandard drugs threaten progress in controlling malaria in Africa, researchers report

Afghan President Karzai urges Taliban to allow polio vaccination teams into insurgent-controlled areas

Researchers develop simple process for synthesis of artemisinin

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