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Scientists develop new experimental diagnostic test to distinguish infection from disease

A potential new experimental diagnostic test able to quickly distinguish individuals with active tuberculosis from those with latent TB infection has been developed. If the preliminary results of the study will be confirmed in a larger population sample, the new diagnostic system could allow more effective strategies to control the spread of the re-emerging pathology.

1 Apr 2011

New findings from two modeling studies can help reduce HCV-related deaths in Europe

New findings from two modeling studies presented at the International Liver Congress support the call to action from medical experts and patients in relation to the challenge health inequalities represent in the diagnosis and access to HCV treatment.

1 Apr 2011

California State Controller urges Merck, Tibotec and ViiV to reduce AIDS drug prices

Today AIDS Healthcare Foundation (AHF) announced that California State Controller John Chiang has sent letters to the CEOs of Merck & Co., Tibotec Therapeutics and ViiV Healthcare, asking the companies to reduce the price of their HIV/AIDS medications for California and its AIDS Drug Assistance Program (ADAP).

1 Apr 2011

Lymphocyte-hepatocyte interactions: Hepatitis C virus changes the rules

New data presented at the International Liver CongressTM today show the existence of novel interactions between T cells and hepatocytes that are regulated by HCV infection, providing a novel understanding of how HCV persists in the liver.

1 Apr 2011

HIV prevention, treatment must be expanded in Asia-Pacific, delegates at regional meeting say

More needs to be done to prevent the spread of HIV/AIDS and increase access to treatments for patients living with the disease, according to representatives from 24 Asia-Pacific countries attending a regional United Nations meeting in Bangkok this week, VOA News reports.

1 Apr 2011

Potential HIV vaccine component undergoes dramatic protein rearrangement

An international study headed by a UC Davis scientist describes how a component of a potential HIV vaccine opens like a flower, undergoing one of the most dramatic protein rearrangements yet observed in nature. The finding could reveal new targets for vaccines to prevent HIV infection and AIDS. A paper describing the work was published online this week in the journal Proceedings of the National Academy of Sciences.

1 Apr 2011

Scientists engineer new protein that prevents HIV virus entry into cells

In what could be a potential breakthrough in the battle against AIDS and a major development in the rational design of new drugs, scientists have engineered a new protein that prevents the virus from entering cells.

1 Apr 2011

EPIDEMICS³ International Conference on Infectious Disease Dynamics to take place in Boston, in Nov 2011

Following the inaugural Epidemics¹ Conference in Asilomar, USA in 2008, and the second conference Epidemics² in Athens, Greece in 2009, both highly successful meetings with both more than 230 participants, the organizers are pleased to announce that the Third International Conference on Infectious Disease Dynamics - EPIDEMICS³ - will take place in Boston, USA, in November 2011.

1 Apr 2011

New research finds HIV virus's V3 loop as attractive vaccine target

A section of the AIDS virus's protein envelope once considered an improbable target for a vaccine now appears to be one of the most promising, new research by Dana-Farber Cancer Institute scientists indicates.

1 Apr 2011

U.N. Secretary-General releases report assessing global response to HIV/AIDS

Nearly 30 years since researchers first described HIV/AIDS, U.N. Secretary-General Ban Ki-moon on Thursday in Nairobi, Kenya, released a report assessing the global HIV/AIDS response, Agence France-Presse reports.

1 Apr 2011

Study: Pseudokinases can play a crucial role in pathogen-based disease

Researchers from the University of Pittsburgh and Stanford University discovered that a supposedly inactive protein actually plays a crucial role in the ability of one the world's most prolific pathogens to cause disease, findings that suggest the possible role of similarly errant proteins in other diseases.

1 Apr 2011

Novartis, Intercell to initiate Pseudomonas vaccine trial in ventilated ICU patients

Today Intercell AG announced that it has agreed with Novartis to advance Intercell's investigational Pseudomonas aeruginosa vaccine into a confirmatory clinical efficacy trial in ventilated ICU patients.

1 Apr 2011

Tibotec presents TMC435 phase 2b study interim results against HCV at EASL meeting

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, announces that their partner, Tibotec has presented the results of a planned Week 24 interim analysis of the phase 2b ASPIRE study for TMC435 in treatment experienced hepatitis C patients in a late-breaker session at the 46th Annual meeting of the European Association for the Study of the Liver, Berlin, Germany.

1 Apr 2011

New data confirms antiviral activity of fluvastatin in patients with HCV

New data presented today at the International Liver CongressTM confirm the antiviral activity of fluvastatin -- commonly used as a cholesterol-lowering treatment -- in patients with chronic hepatitis C.

1 Apr 2011

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced results from several new data analyses from the pivotal Phase III studies evaluating the addition of its investigational oral protease inhibitor VICTRELIS to peginterferon alfa-2b and ribavirin in adult patients with chronic hepatitis C virus genotype 1 infection.

1 Apr 2011

DNA damage can lead to regulation of inflammatory responses

Researchers offer the first evidence that DNA damage can lead to the regulation of inflammatory responses, the body's reaction to injury. The proteins involved in the regulation help protect the body from infection.

1 Apr 2011

Study: Electronic faucets more likely to become contaminated with bacteria

Researchers at The Johns Hopkins University School of Medicine have determined that electronic faucets are more likely to become contaminated with unacceptably high levels of bacteria, including Legionella spp., compared with traditional manually operated faucets.

1 Apr 2011

Vertex announces final results from Phase 3 REALIZE study against HCV

Vertex Pharmaceuticals Incorporated today announced final results from its pivotal Phase 3 REALIZE study that evaluated people with genotype 1 chronic hepatitis C whose prior treatment with pegylated-interferon and ribavirin was unsuccessful either because they relapsed, had a partial response or had a null response.

1 Apr 2011

Biota Scientific receives BARDA contract to develop single-dose antiviral drug

A contract has been awarded to develop a long-acting single-dose antiviral drug for use in the United States, the U.S. Biomedical Advanced Research and Development Authority announced today.

1 Apr 2011

Hands-free electronic water faucets more likely to be contaminated with hazardous bacteria

A study of newly installed, hands-free faucets at The Johns Hopkins Hospital, all equipped with the latest electronic-eye sensors to automatically detect hands and dispense preset amounts of water, shows they were more likely to be contaminated with one of the most common and hazardous bacteria in hospitals compared to old-style fixtures with separate handles for hot and cold water.

1 Apr 2011

Disease/Infection News

Scientists develop new experimental diagnostic test to distinguish infection from disease

New findings from two modeling studies can help reduce HCV-related deaths in Europe

California State Controller urges Merck, Tibotec and ViiV to reduce AIDS drug prices

Lymphocyte-hepatocyte interactions: Hepatitis C virus changes the rules

HIV prevention, treatment must be expanded in Asia-Pacific, delegates at regional meeting say

Potential HIV vaccine component undergoes dramatic protein rearrangement

Scientists engineer new protein that prevents HIV virus entry into cells

EPIDEMICS³ International Conference on Infectious Disease Dynamics to take place in Boston, in Nov 2011

New research finds HIV virus's V3 loop as attractive vaccine target

U.N. Secretary-General releases report assessing global response to HIV/AIDS

Study: Pseudokinases can play a crucial role in pathogen-based disease

Novartis, Intercell to initiate Pseudomonas vaccine trial in ventilated ICU patients

Tibotec presents TMC435 phase 2b study interim results against HCV at EASL meeting

New data confirms antiviral activity of fluvastatin in patients with HCV

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

DNA damage can lead to regulation of inflammatory responses

Study: Electronic faucets more likely to become contaminated with bacteria

Vertex announces final results from Phase 3 REALIZE study against HCV

Biota Scientific receives BARDA contract to develop single-dose antiviral drug

Hands-free electronic water faucets more likely to be contaminated with hazardous bacteria

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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