Disease/Infection News

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Vaccinating through salivary glands may provide protection against wide range of diseases

If you don't like shots or needles, you're in luck. New research published online in The FASEB Journal gives the development of new oral vaccinations a shot in the arm thanks to discoveries involving the salivary glands of mice. In addition, this research report also offers a tantalizing glimpse of vaccines that could prevent infection at mucosal surfaces, even if direct injections into the body fail to cause immunity. This technique may be effective for a wide range of diseases from influenza to cholera.

11 Feb 2011

FDA grants Inhibitex Fast Track Designation for INX-189 in treatment of chronic hepatitis C viral infection

Inhibitex, Inc. today reported that the U.S. Food and Drug Administration ("FDA") has designated the investigation of INX-08189, a potent guanosine nucleotide polymerase inhibitor for the treatment of chronic hepatitis C viral infection, as a Fast Track development program.

11 Feb 2011

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry and Cell Biology entitled, "TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P."

11 Feb 2011

RF-induced heat therapy could help treat common parasitic skin infection

Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.

11 Feb 2011

Anacor, Medicis collaborate to discover and develop boron-based treatment for acne

Anacor Pharmaceuticals, Inc. and Medicis Pharmaceutical Corporation today announced that the two companies have entered into a research and development agreement to discover and develop boron-based small molecule compounds directed against a target for the potential treatment of acne.

11 Feb 2011

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

A three-year, $3 million gift from the Richard J. Fasenmyer Foundation will fund research by a pair of Cleveland physicians into HIV and the body's response in autoimmune diseases.

11 Feb 2011

Rapid GBS test useful adjunct to third trimester culture for accurate GBS detection at time of labor

In a study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting -, in San Francisco, researchers will present findings that show that many women are having different test results for Group B streptococcus (GBS) between their routine third trimester screening and a rapid test performed at the time of labor.

11 Feb 2011

Viral infection of Leishmania leads to increased pathogenicity

A parasite and a virus may be teaming up in a way that increases the parasite's ability to harm humans, scientists at the University of Lausanne in Switzerland and Washington University School of Medicine in St. Louis report this week in Science.

11 Feb 2011

Study finds too low drug concentrations used for treatment of children with TB

The realization of medically treating different children uniquely may start with one of the deadliest diseases in existence: tuberculosis.

11 Feb 2011

£160,000 award to devise anti-microbial collar to prevent bacterial infections associated with broken bones

Orthopaedic experts at The University of Nottingham are hoping to reduce the rate of infections that often occur in the pinning of broken bones by developing a special collar to counter dangerous microbes.

11 Feb 2011

Times of India examines dengue vaccine trials

India could soon become a site for clinical trials to evaluate the effectiveness of a dengue vaccine, the Times of India reports. According to the drug controller general of India, vaccine maker Sanofi Pasteur recently submitted a proposal to test the vaccine to the country.

11 Feb 2011

Medivir initiates phase 1a clinical trial of TMC649128 for chronic HCV infection

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, today announces the start of a phase 1a clinical trial with TMC649128 intended for the treatment of chronic hepatitis C virus infection.

10 Feb 2011

Global Health Consortium to support development of vaccines to control dengue fever

The International Vaccine Institute today announced the launch of the Dengue Vaccine Initiative, in collaboration with the Sabin Vaccine Institute, the Johns Hopkins University, and the World Health Organization, to support development of vaccines to control dengue fever, a widespread and expanding hemorrhagic fever that is endemic in most tropical and subtropical regions of the world.

10 Feb 2011

Gilead resubmits NDA for single-tablet regimen of Truvada/TMC278

Gilead Sciences, Inc. announced today that it has refiled a New Drug Application (NDA) with the U.S. Food and Drug Administration (FDA) for the single-tablet regimen of Truvada® (emtricitabine and tenofovir disoproxil fumarate) and Tibotec Pharmaceuticals' investigational non-nucleoside reverse transcriptase inhibitor TMC278 (rilpivirine hydrochloride) for HIV-1 infection in adults.

10 Feb 2011

Key advance in development of fast, simple test for detection of cholera

With cholera on the rampage in Haiti and almost 40 other countries, scientists are reporting the development of a key advance that could provide a fast, simple test to detect the toxin that causes the disease. The report appears in ACS' journal Bioconjugate Chemistry. Cholera affects more than 200,000 people annually, mainly in developing countries, and causes about 5,000 deaths. Many involve infants, children, and the elderly.

10 Feb 2011

Avian flu vaccine stockpiled in 2004 still useful

A stockpiled vaccine designed to fight a strain of avian flu that circulated in 2004 can be combined with a vaccine that matches the current strain of bird flu to protect against a potential pandemic, researchers from Saint Louis University's Center for Vaccine Development have found.

10 Feb 2011

Idenix announces updates on HCV and HIV clinical development programs

Idenix Pharmaceuticals, Inc., a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today announced updates to three clinical development programs.

10 Feb 2011

Global Hygiene Council: Three simple steps to keep your family protected against infections

The Global Hygiene Council, a group of leading health and hygiene experts from around the world, convened in collaboration with the Centers for Disease Control and Prevention to discuss how proper hygiene plays a critical role in preventing the spread of illness and improving health around the world.

10 Feb 2011

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Cell Medica, a leading UK cellular therapeutics company that develops, manufactures and markets cellular immunotherapy products for the treatment of infectious disease and cancer, announces today that the first patient has been treated in the CMV~ACE/ASPECT trial at University College Hospital London.

10 Feb 2011

Akonni signs license agreement with USAMRIID to develop multiplex testing products for bio-security applications

Akonni Biosystems, a molecular diagnostics (MDx) company that develops rapid, low-cost and highly scalable solutions for infectious disease testing, today announced it has signed a license agreement with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

10 Feb 2011

Disease/Infection News

Vaccinating through salivary glands may provide protection against wide range of diseases

FDA grants Inhibitex Fast Track Designation for INX-189 in treatment of chronic hepatitis C viral infection

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

RF-induced heat therapy could help treat common parasitic skin infection

Anacor, Medicis collaborate to discover and develop boron-based treatment for acne

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

Rapid GBS test useful adjunct to third trimester culture for accurate GBS detection at time of labor

Viral infection of Leishmania leads to increased pathogenicity

Study finds too low drug concentrations used for treatment of children with TB

£160,000 award to devise anti-microbial collar to prevent bacterial infections associated with broken bones

Times of India examines dengue vaccine trials

Medivir initiates phase 1a clinical trial of TMC649128 for chronic HCV infection

Global Health Consortium to support development of vaccines to control dengue fever

Gilead resubmits NDA for single-tablet regimen of Truvada/TMC278

Key advance in development of fast, simple test for detection of cholera

Avian flu vaccine stockpiled in 2004 still useful

Idenix announces updates on HCV and HIV clinical development programs

Global Hygiene Council: Three simple steps to keep your family protected against infections

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Akonni signs license agreement with USAMRIID to develop multiplex testing products for bio-security applications

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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