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P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery

Atherosclerosis is the leading cause of death in the developed world. While a number of risk factors for atherosclerosis have been defined, scientists continue to study other possible risk factors for this disease. Recent epidemiological and experimental studies link infectious agents with the development of inflammatory atherosclerosis. A hallmark of chronic infection with the oral pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response.

5 Jan 2011

Insecticidal nets do not always work against diseases transmitted by insect bites

Longlasting insecticidal nets yielded an important breakthrough in malaria prevention, but this does not automatically mean they always work against diseases transmitted by insect bites. Against the transmission of kala azar disease in India and Nepal they did not have an effect. This was reported by an international group of researchers, led by Marleen Boelaert of the Institute of Tropical Medicine Antwerp, in the reputed British Medical Journal.

5 Jan 2011

Indian government rejects Abbott's patent application for second-line ARV

India's patent office "has rejected American drug maker Abbott Laboratories' patent application for an HIV combination drug, allowing low-cost local drug makers to make and sell their generic versions in India and other countries where the medicine is not patented," Economic Times reports (1/4).

5 Jan 2011

Dongsheng obtains exclusive sales rights of Thymosin Alpha 1 Injection in China

Dongsheng Pharmaceutical International Co., Ltd. announced today that it has obtained the exclusive sales rights of Thymosin Alpha 1 Injection in 19 provinces in China from Shanghai Biochemistry Pharmaceutical Co. I.

5 Jan 2011

Two doses of varicella vaccine provide higher antibody levels than one

When vaccinating children against varicella, researchers at Yale School of Medicine have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

5 Jan 2011

Researchers develop new hand-held instrument for glaucoma screening

A new hand-held instrument involving a system of micro-force sensors, specially designed microchips, and math-based programmed procedures has been designed by researchers at the UA College of Engineering. The easy-to-use probe gently rubs the eyelid and can be used at home, threatening to replace painful eye drops and the need for a sterilized sensor.

5 Jan 2011

Seattle Times looks at response to Haitian cholera outbreak on the ground

Though Haiti's cholera "epidemic continues to spread, infecting more than 125,000 people and killing more than 3,200," it seems to have "stabilized in" the town of Mirebalais, which is close to the "U.N. camp of Nepalese peacekeepers who are under investigation as a possible source" of the outbreak, the Seattle Times reports in a story outlining how aid groups and health workers are dealing with the situation.

5 Jan 2011

Get examined during Glaucoma Awareness Month

It happens slowly. Over time, a person's vision will get worse. Until one day, that person can no longer see. Glaucoma is the second leading cause of blindness in the United States and worldwide. Unfortunately, there is no cure. Once a person's vision is lost, it cannot be regained. That is why Dr. Bizer's VisionWorld is encouraging people to get an examination during Glaucoma Awareness Month.

5 Jan 2011

FDA lifts clinical hold on Hemispherx's Alferon LDO Phase II study for influenza prevention

Hemispherx Biopharma, Inc. announced today that the Food and Drug Administration (FDA) has lifted a clinical hold on its Phase II, double-blind, adaptive-design, randomized, placebo-controlled, dose-ranging study of Alferon® LDO [oral interferon alfa-n3 (human leukocyte derived)] for the prevention and treatment of influenza.

5 Jan 2011

Anadys begins ANA598 Phase IIb study for hepatitis C

Anadys Pharmaceuticals, Inc. announced today that it has initiated the planned Phase IIb study of ANA598 in combination with pegylated interferon and ribavirin. The protocol for the study has been cleared by the United States Food and Drug Administration and Health Canada.

4 Jan 2011

Flu outbreak peak yet to come: Experts

Parents of kids returning to school in the UK after Christmas holidays have been warned of a surge in flu cases. Professor John Oxford, a leading virologist at St Bartholomew’s and the Royal London Hospital explained that children returning to school in the past prompted a rise in the number of flu cases. “You tend to get a surge,” the professor said. “I would anticipate a surge, but how long that will last is difficult to say.” He added, “This virus is not going to go away next week. Even if it’s already peaked, it’s still going to be around for the next couple of weeks and it’s still worthwhile being vaccinated at this stage.”

4 Jan 2011

Hepatitis A scare at Long Island church

Health officials have warned that parishioners who received Holy Communion during Christmas Mass at a church on Long Island may have been exposed to hepatitis A and may need vaccinated as soon as possible. Particularly those who received Communion at the 10.30am and 12pm (local time) masses on December 25, 2010, at Our Lady of Lourdes Church in Massapequa Park should get the shots.

4 Jan 2011

Trial to eliminate deadly Dengue begins

The 12 week programme costing $18 million named ‘Eliminate Dengue’ has commenced. Mosquitoes bearing a special bacteria would be released into the wild around Cairns as part of a trial to rid the area of the insects that carry Dengue fever.

4 Jan 2011

AHF to supply $1 million in free AIDS drugs to Florida's disenrolled and wait listed HIV/AIDS patients

As the State of Florida grapples with a budget shortfall that has crippled its AIDS Drug Assistance Program (ADAP) and forced the state to potentially disenroll 350 Florida patients already on ADAP as well as place nearly 2,400 low-income Floridians on waiting lists to access lifesaving medications, AIDS Healthcare Foundation (AHF) has proposed an innovative plan to help state health officials and displaced HIV/AIDS patients bridge the transition to private patient assistance programs run by the major pharmaceutical companies.

4 Jan 2011

ImmuVen to develop T cell receptor proteins for treating MRSA, cancer

Start-up company ImmuVen and the University of Illinois Urbana-Champaign have entered into a license agreement under which ImmuVen will develop modified T cell receptor proteins for the purpose of treating cancer and methicillin-resistant Staphylococcus aureus.

4 Jan 2011

FDA clears first automated molecular tests to diagnose and differentiate HSV infection

BD Diagnostics, a segment of BD, announced today that it filed for U.S. Food and Drug Administration 510(k) clearance for the first fully automated molecular tests to diagnose and differentiate HSV types 1 and 2.

From BD (Becton, Dickinson and Company) 4 Jan 2011

The Scientist examines how nonprofit, for-profit pharma groups are working together to make drugs more affordable for developing countries

"With philanthropists funneling billions of dollars into biomedical research and traditional drug discovery efforts producing fewer and fewer therapies, the line between for-profit and nonprofit life science companies is beginning to blur as both sides of the divide look for new options," The Scientist magazine writes in an article that examines the rise in collaborations between nonprofit pharmaceutical companies and for-profit groups.

4 Jan 2011

Disease/Infection News

P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery

Insecticidal nets do not always work against diseases transmitted by insect bites

Indian government rejects Abbott's patent application for second-line ARV

Dongsheng obtains exclusive sales rights of Thymosin Alpha 1 Injection in China

Two doses of varicella vaccine provide higher antibody levels than one

Researchers develop new hand-held instrument for glaucoma screening

Seattle Times looks at response to Haitian cholera outbreak on the ground

Get examined during Glaucoma Awareness Month

FDA lifts clinical hold on Hemispherx's Alferon LDO Phase II study for influenza prevention

Anadys begins ANA598 Phase IIb study for hepatitis C

Flu outbreak peak yet to come: Experts

Hepatitis A scare at Long Island church

Trial to eliminate deadly Dengue begins

AHF to supply $1 million in free AIDS drugs to Florida's disenrolled and wait listed HIV/AIDS patients

ImmuVen to develop T cell receptor proteins for treating MRSA, cancer

FDA clears first automated molecular tests to diagnose and differentiate HSV infection

The Scientist examines how nonprofit, for-profit pharma groups are working together to make drugs more affordable for developing countries

Pandemic flu toolkit for nursing facilities

New ATS guidelines for treating fungal infection in adult pulmonary and critical care patients

Mothers can play a key role in convincing college-aged women to receive HPV vaccine

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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