Disease/Infection News

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Adelaide man guilty of deliberately spreading HIV

An Adelaide man, Stuart McDonald, 43, has been accused of deliberately infecting his sexual partners with HIV. He has been found guilty of two counts of endangering life.

14 Dec 2010

DARPA awards Pulmatrix $5.7 million grant to advance iCALM therapies

Pulmatrix, a clinical stage biotechnology company discovering and developing a new class of therapies for the prevention, treatment and control of respiratory diseases, today announced that it has been awarded a grant for $5.7 million from the Defense Advanced Research Projects Agency (DARPA), a component of the Department of Defense (DOD), focused on identifying and advancing novel technologies to support defense of our nation's soldiers and civilian population.

14 Dec 2010

Provectus commences PH-10 Phase 2c trial for psoriasis

Provectus Pharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, has initiated a Phase 2c clinical trial of PH-10 for psoriasis. This multicenter, randomized controlled Phase 2c study is expected to enroll up to 90 subjects at four different sites, beginning in late December.

14 Dec 2010

Pharmasset initiates dosing in PSI-7977 exploratory study in HCV

Pharmasset, Inc. announced today that dosing has begun in an exploratory study of PSI-7977, a nucleotide analog polymerase inhibitor, for the treatment of chronic hepatitis C (HCV). The trial will evaluate PSI-7977 400mg QD in combination with ribavirin (RBV), with 0, 4, 8, or 12 weeks of pegylated interferon alfa 2a (Peg-IFN) in treatment-naive patients infected with HCV genotype 2 or 3.

14 Dec 2010

Scientists discover new way in which HPV triggers cancer

University of Manchester scientists have discovered for the first time an important new way in which the human papilloma virus (HPV) triggers cancer in what could lead to new treatments for cervical and mouth cancer.

14 Dec 2010

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease.

14 Dec 2010

Myths and misunderstandings about medical male circumcision for HIV prevention

A new report from the Women's HIV Prevention Tracking Project (WHiPT), a collaborative initiative of AVAC and the ATHENA Network, features an unprecedented collection of voices from Kenya, Namibia, South Africa, Swaziland and Uganda reflecting on what male circumcision for HIV prevention means for women. It highlights women's perspectives, advocacy priorities and recommendations on this new prevention strategy.

14 Dec 2010

GAVI Alliance launches pneumonia vaccine project in Nicaragua

"A new vaccine against the most deadly forms of pneumonia, one of the world's biggest killers of children, [was] launched in Nicaragua [on Sunday] as part of an effort to prevent 700,000 deaths in poorer countries by 2015," Reuters reports (Kelland, 12/10).

14 Dec 2010

Researchers implement life skills program to reduce HIV and drug use among South African youth

Drug use, risky sexual behavior and violence among South African youth may be reduced thanks to Penn State researchers, who will look at expanding a leisure education and life skills program to 56 South African high schools.

14 Dec 2010

New collaboration to develop vaccine to prevent malaria parasite from entering human liver

Development of a vaccine to prevent the malaria parasite from entering the human liver is the goal of a new collaboration announced today by global leaders in malaria research and vaccine development. The PATH Malaria Vaccine Initiative (MVI), Merck (known outside the US and Canada as MSD), and NYU Langone Medical Center are working together to evaluate an approach targeting a novel part of a major surface protein on the malaria parasite.

14 Dec 2010

Methodist Willowbrook Hospital achieves zero infection rate in top three at-risk categories

In a rare feat for any hospital in the United States, Methodist Willowbrook Hospital in Houston has not recorded a hospital-acquired infection in the top three at-risk areas for 14 consecutive months.

14 Dec 2010

New theory explains spread of infectious diseases

New research using human-networking theory may give a clearer picture of just how, exactly, infectious diseases such as the common cold, influenza, whooping cough and SARS can spread through a closed group of people, and even through populations at large.

14 Dec 2010

Chimerix reports positive results from CMX157 Phase 1 clinical trial for HIV

Chimerix, Inc., a pharmaceutical company developing orally-available antiviral therapeutics, today announced first-in-human Phase 1 clinical trial results for CMX157 demonstrating a favorable safety, tolerability and drug distribution profile.

14 Dec 2010

Clinical trail shows 2009 H1N1 influenza vaccine safe and effective in asthma patients

Results from a government-sponsored clinical trial of inactivated 2009 H1N1 influenza vaccine in people with asthma indicate that a single dose of vaccine was safe and induced a strong immune response predictive of protection.

14 Dec 2010

Go Daddy gifts $500,000 to Southwest Center for HIV/AIDS to launch Women's Health Center in Phoenix

Southwest Center for HIV/AIDS received $500,000 from Go Daddy to launch the Go Daddy Women's Health Center in Phoenix. The gift was announced by Go Daddy CEO and Founder Bob Parsons at the company's annual holiday event held Saturday, December 11 at Chase Field in Phoenix. Parsons presented a 'big check' to Carol Poore, President and CEO, Southwest Center for HIV/AIDS.

14 Dec 2010

Senator Leahy calls for U.S. to suspend direct aid to Haiti's government, visas for Haitian officials

Senator Patrick Leahy (D-Vt.), who chairs the Senate Appropriations Committee's Subcommittee on the State, Foreign Operations, and Related Programs, "on Friday urged President Barack Obama's administration to suspend direct aid to Haiti's government and visas for its top officials until it ensures a fair and democratic outcome to disputed national elections," Reuters reports.

14 Dec 2010

Mouse study shows flu virus infection may protect against asthma

In a paper that suggests a new strategy to prevent asthma, scientists at Children's Hospital Boston and their colleagues report that the influenza virus infection in young mice protected the mice as adults against the development of allergic asthma.

14 Dec 2010

Top-line results from Inhibitex's FV-100 Phase II clinical trial for treatment of shingles

Inhibitex, Inc. today reported top-line safety and efficacy data from its Phase II clinical trial of FV-100, an oral antiviral compound being developed to treat herpes zoster, more commonly referred to as shingles. The study was the first clinical trial to assess the antiviral activity of FV-100, included 350 shingles patients and compared two once-daily doses of FV-100 (200 mg and 400 mg) to an active control, valacyclovir, one of the most commonly-used antiviral drugs to treat shingles.

14 Dec 2010

PREZISTA/ritonavir once-daily dosing for HIV-1 receives FDA approval for treatment in no DRV RAM adults

Tibotec Therapeutics, a division of Centocor Ortho Biotech Products, L.P., announced today that the U.S. Food and Drug Administration (FDA) has approved a revision to the dosing recommendation to include once-daily dosing of PREZISTA® (darunavir) tablets in combination with ritonavir for the treatment of human immunodeficiency virus (HIV-1) in treatment-experienced adult patients with no darunavir resistance-associated mutations (DRV RAMs).

13 Dec 2010

TRL, Anaphore partner to develop novel protein therapies for autoimmune diseases

Tanabe Research Laboratories U.S.A. Inc., (TRL) announced today that it has entered into a partnership with Anaphore Inc. for the research and preclinical development of novel protein therapies for autoimmune diseases based on Anaphore's proprietary Atrimer™ technology.

13 Dec 2010

Disease/Infection News

Adelaide man guilty of deliberately spreading HIV

DARPA awards Pulmatrix $5.7 million grant to advance iCALM therapies

Provectus commences PH-10 Phase 2c trial for psoriasis

Pharmasset initiates dosing in PSI-7977 exploratory study in HCV

Scientists discover new way in which HPV triggers cancer

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

Myths and misunderstandings about medical male circumcision for HIV prevention

GAVI Alliance launches pneumonia vaccine project in Nicaragua

Researchers implement life skills program to reduce HIV and drug use among South African youth

New collaboration to develop vaccine to prevent malaria parasite from entering human liver

Methodist Willowbrook Hospital achieves zero infection rate in top three at-risk categories

New theory explains spread of infectious diseases

Chimerix reports positive results from CMX157 Phase 1 clinical trial for HIV

Clinical trail shows 2009 H1N1 influenza vaccine safe and effective in asthma patients

Go Daddy gifts $500,000 to Southwest Center for HIV/AIDS to launch Women's Health Center in Phoenix

Senator Leahy calls for U.S. to suspend direct aid to Haiti's government, visas for Haitian officials

Mouse study shows flu virus infection may protect against asthma

Top-line results from Inhibitex's FV-100 Phase II clinical trial for treatment of shingles

PREZISTA/ritonavir once-daily dosing for HIV-1 receives FDA approval for treatment in no DRV RAM adults

TRL, Anaphore partner to develop novel protein therapies for autoimmune diseases

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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