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Pharmasset's PSI-938 phase I monotherapy trial shows positive result for HCV treatment

Pharmasset, Inc. reported positive preliminary results today from its phase I monotherapy trial of PSI-352938 for the treatment of chronic hepatitis C (HCV). PSI-938 is a guanosine nucleotide analog polymerase inhibitor in development for the treatment of chronic HCV infection.

28 Oct 2010

NMA/NBNA releases new consensus report on RSV

Today, the National Medical Association (NMA) and the National Black Nurses Association (NBNA) released a consensus report on RSV. Concerned that recent clinical guidelines published by the American Academy of Pediatrics Committee of Infectious Disease (AAP/COID) may leave some infants unprotected from RSV, the NMA/NBNA RSV Consensus Panel recommended that additional research be conducted to ensure that physicians provide the maximum protection to infants and children at risk of RSV.

28 Oct 2010

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

A study and review performed by clinicians of PICC Excellence, Inc. found a disinfection cap that dispenses 70% isopropyl alcohol is effective in disinfecting IV needleless connectors after five minutes. The study shows that if a needleless connector is covered and bathed in alcohol by the disinfection cap, no drying time is required to kill nearly all pathogens on the connector.

28 Oct 2010

Abbott provides $180,000 to support recent cholera outbreak in central Haiti

Abbott is providing $180,000 in support to help address the recent cholera outbreak in central Haiti. This includes a $25,000 grant from the Abbott Fund to Partners In Health, and $155,000 in donated Abbott rehydration solutions and antibiotics.

28 Oct 2010

Cholera outbreak in Haiti shows 'slight slowing,' but experts say interventions should continue

Nearly 300 people have died from cholera and 3,612 have been diagnosed with the disease in Haiti's week-old epidemic, Reuters reports, citing numbers from Haitian health authorities.

28 Oct 2010

Scientists determine tertiary structure of TehA membrane protein in Haemophilus bacteria

Proteins are molecular machines that transport substances, catalyze chemical reactions, pump ions, and identify signaling substances. They are chains of amino acids and the individual amino acid sequence is known for many of them. However, the functions a protein can carry out inside the cell are determined by the three-dimensional spatial structure of the protein. Establishing this so-called tertiary structure presents a great challenge to scientists.

28 Oct 2010

H5N1 lethality gene Replikin Count continues to rise in 2010

BioRadar™ software correctly predicted the 2009 H1N1 (Swine Flu) outbreak a year in advance. The same rise in Replikin Count of these genomic Replikin genes, this time in the H5N1 (Bird Flu) virus, may similarly warn of the coming of severe outbreaks in H5N1.

28 Oct 2010

ChemoCentryx reports one-year study results of Traficet-EN in Crohn's disease patients

ChemoCentryx, Inc., today announced that it reported one-year results from the Company's PROTECT-1 Study (the Prospective Randomized Oral Therapy Evaluation in Crohn's disease Trial) of Traficet-EN™ (CCX282-B) in patients with moderate-to-severe Crohn's disease. Traficet-EN, an orally bioavailable CCR9-specific chemokine receptor antagonist showed clinical efficacy in a 12-week Induction period, as well as a 36-week Maintenance period.

28 Oct 2010

New findings suggest way to treat lung diseases

A new study of an exotic, infectious virus that has caused three recent outbreaks in the United States reveals clues to how the virus might damage lungs during infection. The findings also suggest possible new ways to treat lung diseases in humans.

28 Oct 2010

Omnyx initiates research testing of digital pathology platform

GE Healthcare and UPMC announced today that their imaging joint venture, Omnyx, is initiating clinical research testing of a breakthrough digital pathology platform that is expected to help transform the 125-year-old practice of pathologists using glass slides.

28 Oct 2010

Reuters examines development progress of microbicide gel to prevent HIV

Reuters reports that the developers of a vaginal microbicide gel containing the antiretroviral tenofovir, which has been found to reduce "HIV infections in women by 39 percent," said the FDA last week granted fast-track approval designation to the gel.

28 Oct 2010

Flu deaths analyzed for future lessons

A new report has looked at all of England’s swine flu deaths in children under 18 during the 2009 pandemic. Researchers found that there was a higher risk of dying from the influenza A H1N1 strain of flu among certain groups of children, such as those with pre-existing conditions and those of a Pakistani or Bangladeshi background. However it was unclear why.

27 Oct 2010

Cholera epidemic and political violence dogs upcoming Haiti elections

With elections coming up in Haiti, major earthquakes, a cholera epidemic and fears of political violence rear their ugly heads in the Western Hemisphere's poorest nation. Electoral officials still say the presidential and legislative polls will go ahead as scheduled on November 28, despite the cholera outbreak. The epidemic has killed more than 290 people and sickened more than 4,000 since last week, triggering a major multinational treatment and prevention operation.

27 Oct 2010

Vical to present preclinical results of HSV-2 vaccine program at Keystone Symposium

Vical Incorporated today announced that the company's Vice President of Clinical Development, Richard T. Kenney, M.D., is presenting preclinical results from the company's herpes simplex type 2 (HSV-2) vaccine program in a poster session Friday morning at the Keystone Symposium on Immunological Mechanisms of Vaccination (Seattle, October 27 – November 1).

27 Oct 2010

BioSilta releases EnPresso tablet that regulates protein production in recombinant bacteria

BioSilta announces the release of the EnPresso Tablet Cultivation Set, a tabletised form of the patented EnBase technology. The EnBase technology is based on providing an enzymatic-controlled glucose supply in a fed-batch type manner, which allows an extended growth period and promotes higher final cell density.

27 Oct 2010

Expert shares information on detoxification to promote better health

Cold and flu season is right around the corner, so it's time to start taking the steps to keep your body protected. Natural chelation and detoxification expert, Dr. Isaac Eliaz is re-shaping the way we look at detox methods by examining ways to enhance your body's natural defenses and prevent germs from attacking. Dr. Eliaz has profound information on various modalities of detoxification, including effective detox diets, integrative supplement formulas, lifestyle modifications, and detoxification therapies.

27 Oct 2010

Scripps Florida scientist receives grant from Landenberger Foundation for HIV research

A scientist on the Florida campus of The Scripps Research Institute has received funding from the Philadelphia-based Margaret Q. Landenberger Research Foundation.

27 Oct 2010

Halting mosquito surveillance can increase management costs of epidemics 300 times

Cutting surveillance for mosquito-borne diseases would likely translate into an exponential increase in both the number of human cases and the health costs when a disease outbreak occurs, according to an analysis by Emory University.

27 Oct 2010

New International malaria research consortium to develop novel classes of antimalarials

Research teams from three academic institutions and two private sector companies on two continents have come together to form the International malaria research consortium for the development of novel classes of antimalarials. This bold initiative will develop novel classes of drugs against malaria, a deadly disease in desperate need of new treatments.

27 Oct 2010

Study: lncRNA are involved in host response to viral infection

Scientists have demonstrated for the first time that a certain class of RNA (known as long non-protein-coding RNA [lncRNA]) are involved in the host response to viral infection. These findings, published today in the online journal mBio-, could greatly change the way scientists look at the body's response to viral infection.

27 Oct 2010

Disease/Infection News

Pharmasset's PSI-938 phase I monotherapy trial shows positive result for HCV treatment

NMA/NBNA releases new consensus report on RSV

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

Abbott provides $180,000 to support recent cholera outbreak in central Haiti

Cholera outbreak in Haiti shows 'slight slowing,' but experts say interventions should continue

Scientists determine tertiary structure of TehA membrane protein in Haemophilus bacteria

H5N1 lethality gene Replikin Count continues to rise in 2010

ChemoCentryx reports one-year study results of Traficet-EN in Crohn's disease patients

New findings suggest way to treat lung diseases

Omnyx initiates research testing of digital pathology platform

Reuters examines development progress of microbicide gel to prevent HIV

Flu deaths analyzed for future lessons

Cholera epidemic and political violence dogs upcoming Haiti elections

Vical to present preclinical results of HSV-2 vaccine program at Keystone Symposium

BioSilta releases EnPresso tablet that regulates protein production in recombinant bacteria

Expert shares information on detoxification to promote better health

Scripps Florida scientist receives grant from Landenberger Foundation for HIV research

Halting mosquito surveillance can increase management costs of epidemics 300 times

New International malaria research consortium to develop novel classes of antimalarials

Study: lncRNA are involved in host response to viral infection

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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