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Scientists suggest enzyme that modifies 4-quinolones can reduce microbial infection

So disease-causing bacteria in the body finally have multiplied to the point where their numbers are large enough to cause illness. What's next? They get out their "smart phones" and whisper "Let's roll!" That's how an article in ACS' monthly Chemical Reviews describes the substances "smart phones of the microbial world" that bacteria use to transmit chemical signals that launch infections and monitor their environment.

21 Oct 2010

Protein IL-37 could help treat inflammatory diseases in adults and children

A husband and wife research team from Melbourne, Australia, have identified a protein that may be a key therapy for many inflammatory diseases, including those affecting premature babies.

21 Oct 2010

Researchers investigate reverse zoonosis in marine invertebrate

The spread of lethal diseases from animals to humans has long been an issue of great concern to public health officials. But what about diseases that spread in the other direction, from humans to wildlife. A multidisciplinary team of researchers at the University of Georgia has just been awarded a five-year $2 million Ecology of Infectious Diseases grant from the National Science Foundation and National Institutes of Health to study the first known case of such a "reverse zoonosis" that involves the transmission of a human pathogen to a marine invertebrate, elkhorn coral.

21 Oct 2010

Annual conventional Pap smear is cost effective to reduce cancer incidence and mortality

A study of the options for reducing cancer incidence and mortality among women who have been treated for precancerous cervical lesions found that an annual conventional Pap smear is a cost effective strategy.

21 Oct 2010

Intercell and Romark announce IC41-nitazoxanide combination clinical trials for HCV

Intercell AG and Romark Laboratories L.C. today announced plans to commence clinical trials of Intercell's investigational therapeutic Hepatitis C virus (HCV) vaccine, IC41, in combination with Romark's antiviral drug, nitazoxanide, during the first half of 2011.

21 Oct 2010

LSUHSC receives NIH grant for research on cancer and infectious diseases

LSU Health Sciences Center New Orleans has been awarded $12 million over five years by the National Institutes of Health to conduct research on diseases like prostate and stomach cancers, lymphoma and leukemia, dengue fever, tuberculosis, and herpes infections, as well as to support the development of academic research scientists.

21 Oct 2010

CKI to distribute Allergy Technologies' ActiveGuard mattress liners

Cadence Keen Innovations (CKI) has recently announced that it will be the exclusive distributor of Allergy Technologies' ActiveGuard Mattress Liners, which kill bed bugs within 72 hours, to the cruise industry and other CKI-supported hospitality facilities.

21 Oct 2010

Seven million people in Pakistan still without shelter since flooding, U.N. says

Nearly three months after major floods hit large portions of Pakistan, at least seven million people are still without shelter, Stacey Winston, a U.N. spokesperson, said at a news conference in Islamabad on Tuesday, Agence France-Presse reports.

21 Oct 2010

West, Central African floods kill 377; situation in Benin especially worrying, U.N. says

Floods in west and central Africa have killed 377 people and affected almost 1.5 million people since the start of the rainy season in June, the U.N. Office for the Coordination of Humanitarian Affairs (OCHA), said on Tuesday, Agence France-Presse reports.

21 Oct 2010

SciDev.Net examines plans for India-S. Africa HIV vaccine research project

SciDev.Net reports on an HIV vaccine research collaboration between researchers from India and South Africa to launch by the end of 2010.

21 Oct 2010

Scientists find potential Achilles Heel in JC polyomavirus

The JC polyomavirus doesn't strike very often, but it's a mean bug that preys on people with weakened immune systems, including people with AIDS, and almost always kills them. Now an international team of scientists at Brown University, the University of T-bingen in Germany, and Imperial College in London has found a potential Achilles Heel and painted a target on it: The virus must bind to a very specific sugar molecule dangling from the side of the brain cells it attacks.

21 Oct 2010

Study on health effects of alcohol consumption with HIV

Living with HIV is difficult under the best of circumstances, but for people carrying the virus, alcohol consumption can become particularly perilous in intricate ways that are only beginning to be understood. At the Brown Alcohol Research Center on HIV (ARCH) funded by a new $7.5-million, five-year grant from the National Institutes of Health, Brown University scientists will study the health effects of drinking with HIV and provide doctors and patients with the latest guidance their results suggest.

21 Oct 2010

Researchers to study effect of reovirus on cancer cells

A common virus that can cause coughing and mild diarrhea appears to have a major redemptive quality: the ability to kill cancer. Harnessing that power, researchers at Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center, are conducting a clinical trial to see if the virus can target and kill certain tumor types.

21 Oct 2010

NIH awards $7 million grant to provide sustained care for HIV-positive inmates

The University of Illinois at Chicago has received a $7 million grant from the National Institutes of Health to study effective ways to seek, test, and treat inmates with HIV.

21 Oct 2010

Also in Global Health News: Foreign aid in Ethiopia; Elizabeth Glaser Pediatric AIDS Foundation; Health in Myanmar; Poverty in Zambia; Rwanda's progress on MDGs; Men involved in PMTCT of HIV

Ethiopia's government has been restricting access to food and other types of foreign aid among opposition supporters, Human Rights Watch (HRW) said in a report on Tuesday, Reuters reports (Malone, 10/19). The report is based on more than 200 interviews, conducted over a six-month period in 2009, of people in 53 villages across three regions of the country, according to an HRW press release (10/19).

21 Oct 2010

WILD, Sterling Technology announce partnership for Immunel, Tegricel products

WILD Flavors, Inc. is excited to announce a recently formed partnership with Sterling Technology. This new partnership makes WILD the exclusive provider of both Immunel and Tegricel.

20 Oct 2010

LANL's researcher to implement first human trial of mosaic HIV vaccine candidate

Los Alamos National Laboratory researcher Bette Korber is part of an international team of investigators working to design and implement the first human trial of a mosaic HIV vaccine candidate. The vaccine represents a novel strategy for fighting the virus that causes AIDS by attempting to address one of the most daunting challenges in HIV vaccine design: the virus's extensive genetic diversity.

20 Oct 2010

New sensor uses frog peptides to detect contamination in drugs, medical devices

Princeton engineers have developed a sensor that may revolutionize how drugs and medical devices are tested for contamination, and in the process also help ensure the survival of two species of threatened animals.

20 Oct 2010

New CIMIT Accelerator program spins out HanGenix

A recently formed Boston-based start up called HanGenix is the first company to be spun out of the new CIMIT Accelerator program. HanGenix is focused on reducing hospital acquired infections (HAI) by installing comprehensive hand hygiene solutions that remind clinicians to perform proper hand hygiene and document their compliance.

20 Oct 2010

Study finds massive blood transfusion associated with severe complications

A study presented at this year's American Society of Anesthesiologists Annual Meeting indicates that massive blood transfusion is associated with a significant increase in perioperative risk for mortality, cardiopulmonary complications, and wound-related and infectious complications in the long term.

20 Oct 2010