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Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Observational cohort study of long COVID among 2 million elderly adults

Research estimates the incidence of long COVID and long Flu among Medicare patients using the World Health Organization (WHO) consensus definition. The study compares the incidence, symptomatology, and healthcare utilization between long COVID and long flu patients.

20 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

Can SARS-CoV-2 infection cause diabetes?

This paper reports a population-based cohort study conducted in British Columbia, Canada, which found that SARS-CoV-2 infection is associated with a higher risk of diabetes, particularly among those with severe COVID-19 disease.

19 Apr 2023

Climate change poses risks to aquaculture, threatening food security

This paper investigates the impact of global warming on mortality due to viral infections in farmed aquatic animals. The study found a positive trend between increasing temperature and increasing viral virulence, which could pose a risk of viral disease outbreaks in aquaculture and compromise global food security.

19 Apr 2023

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CAR T-cell therapy.

19 Apr 2023

Infectious particles of the SARS-CoV-2 virus isolated from hospital air

Quebec scientists have succeeded in isolating infectious particles of the SARS-CoV-2 virus from air samples collected from hospital rooms of COVID-19 patients and kept frozen for more than a year, a new study shows.

19 Apr 2023

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Announcing a new article publication for Zoonoses journal. Vaccines are among the most effective medical countermeasures against infectious diseases.

19 Apr 2023

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Researchers explored the possible transmission of SARS-CoV-2 to zoo employees from an African lion.

19 Apr 2023

Is there an association between exposure to ultrafine particles during pregnancy and influenza infection severity?

Researchers explored the impact of exposure to ultrafine particles during pregnancy on the risk of influenza.

19 Apr 2023

Discovery offers a potential target for TB therapies

In ongoing research aimed at developing more effective treatments for tuberculosis (TB), University of Massachusetts Amherst microbiologists have identified a long-sought gene that plays a critical role in the growth and survival of the TB pathogen.

19 Apr 2023

Assessing the efficacy, safety and tolerability of AXA1125 in long COVID patients

Researchers evaluated the effectiveness of endogenous metabolic modulator, AXA1125.

19 Apr 2023

ChatGPT-4 outperforms GPT-3.5 and Google Bard in neurosurgery oral board exam

Researchers evaluate the performance of three large language models (LLMs) on a question bank designed for neurosurgery oral board examination preparation. The study found that GPT-4 achieved the highest score of 82.6%, outperforming ChatGPT and Google's Bard.

19 Apr 2023

Adapting for endemic not pandemic: Time to reassess universal masking in healthcare

Researchers discuss the changing context of universal masking in healthcare settings amid the COVID-19 pandemic and argue for a dynamic, adaptable approach to infection prevention policies.

19 Apr 2023

Global study reveals diet's role in 70% of new type 2 diabetes cases

New research estimates the global burden of type 2 diabetes (T2D) attributable to 11 dietary factors in 184 countries in 1990 and 2018. The study found that suboptimal intake of these dietary factors was responsible for 70.3% of new T2D cases globally in 2018.

19 Apr 2023

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

Research examines the impact of the COVID-19 pandemic on people with intellectual disabilities in the Netherlands. It shows that the mortality risk from COVID-19 was higher in people with intellectual disabilities than in the general population, and overall mortality disparities were further exacerbated during the first 2 years of the pandemic.

18 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Disease/Infection News

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Observational cohort study of long COVID among 2 million elderly adults

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

Can SARS-CoV-2 infection cause diabetes?

Climate change poses risks to aquaculture, threatening food security

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

Infectious particles of the SARS-CoV-2 virus isolated from hospital air

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Is there an association between exposure to ultrafine particles during pregnancy and influenza infection severity?

Discovery offers a potential target for TB therapies

Assessing the efficacy, safety and tolerability of AXA1125 in long COVID patients

ChatGPT-4 outperforms GPT-3.5 and Google Bard in neurosurgery oral board exam

Adapting for endemic not pandemic: Time to reassess universal masking in healthcare

Global study reveals diet's role in 70% of new type 2 diabetes cases

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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