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COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Pieren, D. K. J., Kuguel, S. G., Rosado, J., Robles, A. G., Rey-Cano, J., Mancebo, C., Esperalba, J., Falcó, V., Buzón, M. J., & Genescà, M. (2023). Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37559-w, https://www.nature.com/articles/s41467-023-37559-w

10 Apr 2023

Air pollution lowers COVID-19 vaccine immune response

In a recent study published in the journal Environmental Health Perspectives, researchers performed a population-level cohort study in Catalonia, Spain, to evaluate the association between exposure to air pollution for a prolonged duration and coronavirus disease 2019 (COVID-19) vaccine-induced antibody response.

9 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

Study suggests potential therapeutic targets for COVID-19-related neurological pathologies

In a recent study published in the journal Molecular & Cellular Proteomics, researchers analyzed the proteins in cerebrospinal fluid (CSF) samples obtained from African green monkeys and rhesus macaques infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 to understand the neurological manifestations of coronavirus disease 2019 (COVID-19).

9 Apr 2023

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

A study investigating risk factors and vectors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission reveals that the presence of the virus on the hands of primary and secondary cases and on frequently-touched surfaces is associated with transmission risk. The study is published in the journal THE LANCET Microbe.

9 Apr 2023

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.

7 Apr 2023

Study: Pulse oximeters no better than just asking COVID-19 patients if they are short of breath

Using a pulse oximeter to measure oxygen levels is no better than just regularly asking patients with COVID-19 if they are short of breath, according to new research at the Perelman School of Medicine of the University of Pennsylvania.

7 Apr 2023

Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Adults hospitalized with the SARS-CoV-2 Omicron variant have a higher death rate than those hospitalized with seasonal influenza, even though Omicron is considered less virulent with lower case fatality rates than the delta and alpha strains, new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April) suggests.

7 Apr 2023

Discovery may change the way people think about immune strategies

The human body is capable of creating a vast, diverse repertoire of antibodies - the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.

7 Apr 2023

Study indicates that targeted interventions strengthening HIV antiretroviral therapy initiation are critical

Researchers assessed five-year trends in human immunodeficiency virus viral load suppression rates.

7 Apr 2023

Study explores the association between gut microbiome dysbiosis and uveitis

Researchers provide an overview of existing research on the correlation between uveitis and gut dysbiosis.

7 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Study explores the emerging invasive group A Streptococcus M1uk lineage,

7 Apr 2023

Specific proteins in the blood may help predict which COVID-19 patients may become critically ill

Researchers at Washington University School of Medicine in St. Louis have identified specific proteins that may help predict which COVID-19 patients may need to be placed on ventilators to breathe and which are most likely to die of the virus.

6 Apr 2023

Post-exposure doxycycline approach leads to two-thirds reduction in STI incidence

The oral antibiotic doxycycline prevented the acquisition of sexually transmitted infections (STIs) when tested among men who have sex with men (MSM) and transgender women who took the medication within 72 hours of having condomless sex, according to findings published today in the New England Journal of Medicine.

6 Apr 2023

Prevalence of long-COVID among English schoolchildren: Study reveals wide-ranging impacts on health and wellbeing

Scientists have estimated the prevalence of post-coronavirus disease 2019 (COVID-19) conditions among schoolchildren in England. They have also assessed the presence of persisting symptoms among schoolchildren with or without a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

6 Apr 2023

Disease/Infection News

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Air pollution lowers COVID-19 vaccine immune response

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

Study suggests potential therapeutic targets for COVID-19-related neurological pathologies

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

Study: Pulse oximeters no better than just asking COVID-19 patients if they are short of breath

Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Discovery may change the way people think about immune strategies

Study indicates that targeted interventions strengthening HIV antiretroviral therapy initiation are critical

Study explores the association between gut microbiome dysbiosis and uveitis

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Specific proteins in the blood may help predict which COVID-19 patients may become critically ill

Post-exposure doxycycline approach leads to two-thirds reduction in STI incidence

Prevalence of long-COVID among English schoolchildren: Study reveals wide-ranging impacts on health and wellbeing

Case study shows how COVID-19 breached the placenta and caused brain damage in the baby

Study sheds new light on the spread of COVID-19 in households

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

The economic burden of RSV infections in low and middle-income countries

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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