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Researchers take steps to standardize correlates of protection against SARS-CoV-2

Antibodies, Antibody, Assay, Coronavirus, Efficacy, Healthcare, Pandemic, Protein, Receptor, Research, Vaccine, Virus, Coronavirus Disease COVID-19,

24 May 2021

Shared genetic architecture between COVID-19 severity and other health conditions

Researchers in the United States have identified a shared genetic architecture between coronavirus disease 2019 (COVID-19) severity and other health conditions.

24 May 2021

Could an antiviral mouthwash using silver nanoparticles prevent COVID-19?

In a recent study by researchers in Mexico, Russia and Spain, silver nanoparticles (AgNPs) were found to inhibit SARS-CoV-2 in healthcare workers. They propose a non-pharmaceutical public health intervention consisting of mouthwash and nose rinse with an AgNPs solution to reduce morbidity among healthcare personnel exposed to the SARS-CoV-2 virus.

24 May 2021

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

While drug repurposing has been explored in the context of the current coronavirus disease 2019 (COVID-19) pandemic, the success of this strategy has been limited so far. A new study, released as a preprint on the medRxiv* server, describes a new method of identifying a promising hit among drugs already in use.

24 May 2021

New peptide-like molecules could treat herpes, COVID-19, and the common cold

Among the powerful biochemicals of the human immune system, peptides are one of the best.

24 May 2021

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Even as a host of vaccines have been rolled out to counter the coronavirus disease 2019 (COVID-19) pandemic, some serious adverse effects have been reported, in the form of thrombocytopenia. A new study in the journal Vaccine reports the results of an evaluation of reported cases of this condition, using data from the Vaccine Adverse Event Reporting System (VAERS).

24 May 2021

Novel natural compounds may help treat COVID-19, study suggests

A new study in the journal Chemistry Europe reports two natural compounds identified by virtual screening and computational modeling as having great promise for the development of drugs against SARS-CoV-2.

24 May 2021

How conservative are the current COVID-19 pandemic global statistics?

After almost a year and a half of the COVID-19 pandemic, the actual case count of those infected with its causative virus – SARS-CoV-2 – remains unclear. Though well over 167.2 million cases have been reported worldwide, this is certainly believed by many to be a massive undercount. A new epidemiological study uses the classical SIR-C mathematical model to find the peak size and date of cases, both documented and unidentified, and the gap between them.

24 May 2021

Study: Four-month regimen of anti-TB drugs works just as well as standard regimen

A new four-month regimen of anti-TB drugs that includes rifapentine and moxifloxacin works just as well as the standard six-month regimen, according to a study.

24 May 2021

Mild cases of COVID-19 provide lasting antibody protection, shows study

Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.

24 May 2021

Higher BMI linked to higher survival rates in patients hospitalized for severe bacterial infections

For many diseases, overweight and obesity are risk factors. But now a study shows that a higher BMI may be linked to higher survival rates in patients hospitalized for severe bacterial infections.

24 May 2021

Which biomarkers can help predict adverse outcomes in COVID-19?

A team of researchers has conducted a systematic review to identify laboratory factors that can predict the risk of severe and critical COVID-19 as well as associated mortality rates. The team – from institutions in India and the USA – recently published their findings in the Journal of Clinical Medicine Research.

24 May 2021

Could saffron be an effective supplement for helping manage COVID-19?

A new study, published in the journal Cell Press, explores the potential use of saffron (Crocus sativus L.) as a drug supplement for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19).

24 May 2021

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

The study findings reveal that RBD-based vaccines adjuvanted with the formulation can induce strong anti-SARS-CoV-2 neutralizing immunity in young and aged mice. The study is currently available on the bioRxiv* preprint server.

24 May 2021

Researchers identify factors influencing vaccine hesitancy in USA

A team of scientists from the Washington University, in St. Louis, USA, has recently conducted a survey to analyze factors responsible for coronavirus disease 2019 (COVID-19) vaccination hesitancy among US citizens.

24 May 2021

Genetically engineered intestinal organoids reveal potential treatment targets against SARS-CoV-2

Using CRISPR/Cas9 and human intestinal organoids to study genes implicated in the biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers from the Netherlands identified a specific serine protease (TMPRSS2) as an attractive pan-coronavirus therapeutic target. Their exciting findings are available in a study currently available on the bioRxiv* preprint server.

24 May 2021

Proof that face masks reduce SARS-CoV-2 transmission

Researchers in Germany and China have conducted a study analyzing the efficacy of face masks in mitigating the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

24 May 2021

Research suggests Garcinia kola extract might suppress severe COVID-19 cytokine storms

Researchers in the UK and Nigeria have conducted a study showing that Garcinia kola seed extract and garcinoic acid may provide therapeutic benefits in the late stage of severe coronavirus disease 2019 (COVID-19) and other coronavirus infections.

24 May 2021

STING agonist diABZI shows promise against SARS-CoV-2 variants

COVID-19 vaccines are the most effective way to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. For people who are already infected, new research suggests the small molecule stimulator of interferon genes (STING) agonist-1, diABZI, may be effective in controlling SARS-CoV-2 infection — including those caused by variants.

23 May 2021

Computationally designed peptide blocks the entry of SARS-CoV, SARS-CoV-2, and MERS-CoV

In order to develop effective antiviral drugs, scientists design active molecules based on their structures that can prevent or disrupt the specific viral-receptor binding - this is an effective strategy to prevent the virus from entering the host.

23 May 2021

Disease/Infection News

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Shared genetic architecture between COVID-19 severity and other health conditions

Could an antiviral mouthwash using silver nanoparticles prevent COVID-19?

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

New peptide-like molecules could treat herpes, COVID-19, and the common cold

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Novel natural compounds may help treat COVID-19, study suggests

How conservative are the current COVID-19 pandemic global statistics?

Study: Four-month regimen of anti-TB drugs works just as well as standard regimen

Mild cases of COVID-19 provide lasting antibody protection, shows study

Higher BMI linked to higher survival rates in patients hospitalized for severe bacterial infections

Which biomarkers can help predict adverse outcomes in COVID-19?

Could saffron be an effective supplement for helping manage COVID-19?

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

Researchers identify factors influencing vaccine hesitancy in USA

Genetically engineered intestinal organoids reveal potential treatment targets against SARS-CoV-2

Proof that face masks reduce SARS-CoV-2 transmission

Research suggests Garcinia kola extract might suppress severe COVID-19 cytokine storms

STING agonist diABZI shows promise against SARS-CoV-2 variants

Computationally designed peptide blocks the entry of SARS-CoV, SARS-CoV-2, and MERS-CoV

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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