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Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

Researchers report the association of subgenomic RNA (sgRNA) production, the structural differences between sgRNA variants, and clinical severity in 81 clinical specimens obtained from both asymptomatic and symptomatic individuals with SARS-CoV-2 infection.

9 Feb 2021

Emergence and transmission of UK SARS-CoV-2 variant in the US

Researchers describe the impending rise to dominance of the B.1.1.7 (UK) variant in the US. Understanding this development will help to shape preventive action to reduce the infection and mortality rates.

9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

New book highlights need for rapid, frequent screening to control the pandemic

Covid-19 is a global pandemic inflicting large health and economic costs. In his previous book, The Pandemic Information Gap: The Brutal Economics of COVID-19 (The MIT Press, 2020), economist Joshua Gans explains that those costs have been so large because governments and others have lacked the information needed to control the pandemic.

9 Feb 2021

Delayed reactions and decentralized approach on 1918 pandemic had more fatal consequences

In the event of a pandemic, delayed reactions and a decentralized approach by the authorities at the start of a follow-up wave can lead to longer-lasting, more severe and more fatal consequences, researchers from the universities of Zurich and Toronto have found.

9 Feb 2021

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

World health experts have long suspected that the incidence of COVID-19 has been higher than reported. Now, a machine-learning algorithm developed at UT Southwestern estimates that the number of COVID-19 cases in the U.S. since the pandemic began is nearly three times that of confirmed cases.

8 Feb 2021

Researchers look at long-term outcomes of cancer patients diagnosed with COVID-19

Researchers at MUSC Hollings Cancer Center have joined a nationwide study to look at the long-term outcomes of cancer patients who have been diagnosed with COVID-19.

8 Feb 2021

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, Mount Sinai researchers report in one of the first studies on the topic. The findings were published in the Journal of Medical Internet Research on January 29.

8 Feb 2021

New U.K. SARS-CoV-2 variant may cause more severe illness, study finds

Researchers at the London School of Hygiene and Tropical Medicine revealed that the VOC 202012/01 variant is not only fast-spreading and easily transmissible but also may cause more severe illness.

8 Feb 2021

Type of aspirating system significantly affects SARS-CoV-2 incidence among dental specialists

High-volume aspirators are recommended in dental clinics during the COVID-19 pandemic, but the study "SARS-CoV-2 Seropositivity Among Dental Staff and the Role of Aspirating Systems" published in the JDR Clinical & Translational Research (JDR CTR), shows that the type of aspirating system significantly affects the incidence of SARS-CoV-2 infection among dental specialists.

8 Feb 2021

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

In a new study, published on the pre-print server medRxiv, an international team of researchers found that a one-dose policy may increase the potential for antigenic evolution. The study revealed that focusing on one dose may decrease infections in the short term, but longer-term outcomes rely on this immune strength.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. The team measured 1) IFN-gamma (interferon-gamma) T cell responses, 2) both total IgG Spike/ IgG Spike RBD (receptor binding domain) and 3) neutralizing antibody responses to Spike in sera.

8 Feb 2021

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

An analysis of Kaiser Permanente members in Northern California early in the COVID-19 pandemic found racial and ethnic disparities in the likelihood of testing positive for the coronavirus, but no significant disparities in mortality among those who were hospitalized.

8 Feb 2021

Study examines people's behavioral responses to face mask mandates during the pandemic

Face masks mandates have led people to spend less time at home, but whether this has exposed Americans to more risk is still a question, according to a new study published Thursday in Scientific Reports.

8 Feb 2021

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Moderna's COVID-19 vaccine effective against emerging variants

Researchers have conducted a study showing that the Moderna mRNA-1273 vaccine effectively protects against recently emerged variants of SARS-CoV-2 – the agent that causes COVID-19.

8 Feb 2021

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Researchers at the University of Nebraska Medical Center have developed a bacterial strategy for the expression and purification of the SARS-CoV-2 spike protein receptor-binding domain (RBD).

8 Feb 2021

Is a ten day isolation period for COVID-19 patients long enough?

In a new study researchers at the Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, Brazil, reported that mild COVID-19 patients can still be infectious at day 10 from the illness onset, even in the absence of symptoms.

8 Feb 2021

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

A team of researchers recently examined the SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia.

8 Feb 2021

Disease/Infection News

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

Emergence and transmission of UK SARS-CoV-2 variant in the US

A precursor to remdesivir shows therapeutic potential for COVID-19

New book highlights need for rapid, frequent screening to control the pandemic

Delayed reactions and decentralized approach on 1918 pandemic had more fatal consequences

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

Researchers look at long-term outcomes of cancer patients diagnosed with COVID-19

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods

New U.K. SARS-CoV-2 variant may cause more severe illness, study finds

Type of aspirating system significantly affects SARS-CoV-2 incidence among dental specialists

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

HIV: New therapeutic approach to restore the effectiveness of immune cells

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

Study examines people's behavioral responses to face mask mandates during the pandemic

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Moderna's COVID-19 vaccine effective against emerging variants

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Is a ten day isolation period for COVID-19 patients long enough?

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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