Drug Discovery & Pharmaceuticals

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Government’s £2 billion plan sets out to harness the power of engineering biology

The government's £2 billion vision to seize the enormous potential of engineering biology - an exciting field of biology which could transform how we sustainably grow food, create medical treatments and produce fuel - will be unveiled by Science, Research and Innovation Minister Andrew Griffith today (Tuesday 5 December).

5 Dec 2023

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) and Celdara Medical today announced the signing of a Memorandum of Understanding (MOU) aimed at identifying and advancing promising new therapeutics in areas of high unmet medical need.

29 Nov 2023

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Insilico Medicine ("Insilico"), an artificial intelligence (AI)-driven, clinical stage biotechnology company and leader in AI drug discovery platform technology, is hosting three webinars unveiling its latest technology breakthroughs Nov. 28-30, 2023.

29 Nov 2023

AI predicts ideal sites for chemical alterations in drug molecules

Researchers have developed an AI model that can predict where a drug molecule can be chemically altered.

29 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Almirall S.A., a global biopharmaceutical company focused on medical dermatology, and Absci Corporation, a generative AI drug creation company, today announced a drug discovery partnership aimed to develop and commercialize AI-designed therapeutics to fight chronic and debilitating dermatological diseases. The partnership combines Absci’s Integrated Drug Creation™ platform with Almirall’s dermatological expertise with the goal of delivering life-changing medicines to patients, marking another step forward in AI drug creation.

20 Nov 2023

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer.

17 Nov 2023

MaxCyte joins the Alliance for mRNA Medicines (AMM) as a founding member

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and innovative bioprocessing applications, today announced that it has joined the Alliance for mRNA Medicines (AMM), as a founding member.

From MaxCyte, Inc. 16 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

Slumbering among thousands of bacterial strains in a collection of natural specimens at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, several fragile vials held something unexpected, and possibly very useful.

13 Nov 2023

New hope for TB patients as UNITE4TB launches clinical trial program

Today, UNITE4TB, an international public-private partnership striving to fast-track the development of innovative Tuberculosis (TB) treatments, announced the start of its phase 2B/C clinical trial program with the first participant enrolled at its trial site in Cape Town, South Africa.

13 Nov 2023

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

New benchmark of solid-solid free energy differences paves way for better pharmaceutical design

Physical properties (stability, solubility, etc.), critical to the performance of pharmaceutical and functional materials, are known to strongly depend on the solid-state form and environmental factors, such as temperature and relative humidity.

10 Nov 2023

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

10 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

In a recent study published in npj Regenerative Medicine, researchers discuss the ability of melanin nanoparticles to support wound recovery in mice. The effects at histological and gene levels were explored and confirmed on biomimetic models and human skin explants.

5 Nov 2023

TUM start-up nominated for Science Breakthrough of the Year at Falling Walls summit

It all began with basic research: While conducting laboratory experiments, a team at the Technical University of Munich (TUM) came across an active agent against multidrug-resistant bacteria with a fundamental difference to antibiotics developed to date.

2 Nov 2023

Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

Global sustainable laboratory equipment visionaries, Asynt, have collaborated with Kingston University (London, UK) and renowned worldwide chemical products supplier, Key Organics, to develop an accessible new synthetic compound library.

From Asynt 2 Nov 2023

Bridging Chemistry and Biology: The Art of Designing Novel Therapeutics

In this interview, we delve into the journey and research of Sona Krajcovicova, exploring how diverse interests led to a passionate pursuit of chemistry, innovative approaches to drug development, and a commitment to making a meaningful impact on the world of therapeutics.

2 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Drug Discovery & Pharmaceuticals

Government’s £2 billion plan sets out to harness the power of engineering biology

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

AI predicts ideal sites for chemical alterations in drug molecules

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

MaxCyte joins the Alliance for mRNA Medicines (AMM) as a founding member

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

New hope for TB patients as UNITE4TB launches clinical trial program

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

New benchmark of solid-solid free energy differences paves way for better pharmaceutical design

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

Scientists discover kidney-friendly antifungal that evades resistance

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

TUM start-up nominated for Science Breakthrough of the Year at Falling Walls summit

Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

Bridging Chemistry and Biology: The Art of Designing Novel Therapeutics

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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