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Viramidine demonstrates anti-HCV Genotype 1 activity that compares favorably to Ribavirin

Dose-limiting anemia can be a prominent adverse event of therapy with pegylated interferon and ribavirin. This dose-ranging study examined whether viramidine, a liver-targeting prodrug of ribavirin, may be a safer alternative when used in combination with pegylated interferon alfa-2a/ PEG-IFN (Pegasys).

23 Apr 2005

Obesity and insulin resistance fuels cardiovascular risk factors in teens

Obesity and insulin resistance are a menacing tag team that fuels cardiovascular risk factors in teens, according to a study reported in an obesity-themed issue of Circulation: Journal of the American Heart Association.

23 Apr 2005

Being chubby means you may be healthier!

A new study is saying that being overweight may not be the killer we once thought it was and the number of deaths each year attributed to obesity and being overweight in the United States is around 112,000 - about one-quarter of the previous estimate of more than 400,000 deaths.

23 Apr 2005

Teens get high on painkillers

The latest study, by a group called the Partnership for a Drug-Free America, has found that approximately one in five teenagers have tried to get high by using prescription painkillers such as Vicodin and OxyContin which they often find in their parents' medicine cabinets.

23 Apr 2005

Surgery reduces seizures and increases IQ for kids with epilepsy

A study on 50 preschool-aged children with epilepsy who underwent surgical treatment showed significant improvements on overall cognitive development and left many seizure-free. The article is published in the journal Epilepsia.

22 Apr 2005

High levels of immunosuppressant may lead to tumor recurrence

A new study on the incidence of liver cancer after transplant found that high levels of the immunosuppressant cyclosporine favored tumor recurrence and identified blood levels of the drug that should not be exceeded. Lower levels of cyclosporine levels did not affect rejection rates.

22 Apr 2005

Brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism

A new mouse study suggests that a brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism. Mice with a mutation in a gene called "Clock," which helps drive circadian rhythm, ate significantly more and gained more weight.

22 Apr 2005

Cancer patients may one day benefit from treatment with mixtures of customized antibodies

In a study published recently in the Proceedings of the National Academy of Sciences (USA), a team of Weizmann Institute scientists have demonstrated how the right combination might form a web that destroys the cancer cell's communication network, ultimately demobilizing the cell.

22 Apr 2005

One step closer to personalized medical treatment

A new study by 64 renowned scientists may bring us one step closer to personalized medical treatment--that is, medical treatment tailored to each person's unique genetic make-up and medical condition.

22 Apr 2005

Neural tube defects decrease with folic acid fortification

A new study published online April 21, 2005 in the American Journal of Medical Genetics Part A examines whether the recent decline in neural tube defects in Chile was due to the addition of folic acid to wheat flour in that country or to pre-existing decreasing trends. The journal is available online via Wiley InterScience.

21 Apr 2005

With a complement, the sperm gets the egg

When a sperm fuses with an egg, a specific reaction takes place that exposes the inner membrane of the spermatozoa, where a protein called the complement regulator membrane cofactor protein (MCP) is expressed. MCP is an immune regulatory molecule and its presence in reproductive tissues was unclear.

21 Apr 2005

CDC playing politics over obesity

Leaders at Centers for Disease Control and Prevention (CDC) were criticized by The Center for Consumer Freedom (CCF) today for playing politics over obesity.

20 Apr 2005

Clinical study of MDX-010/MDX-1379 combination shows durable responses in patients with metastatic melanoma

Medarex, Inc. and Bristol-Myers Squibb Company announced today that complete or partial responses in seven of 56 patients with metastatic melanoma showed durability ranging from four months to the longest still ongoing at over 34 months, with five of the seven responses ongoing for more than two years.

20 Apr 2005

Meat Institute defends hot dogs in recent pancreatic cancer study

In response to the report released today at the American Association for Cancer Research in Anaheim, California, attempting to link processed meats to pancreatic cancer, James L. Hodges, President of the American Meat Institute Foundation made the following comment:

20 Apr 2005

Eating hot dogs increases risk of pancreatic cancer

Heavy consumption of hot dogs, sausages and luncheon meats, along with other forms of processed meat, was associated with the greatest risk of pancreatic cancer in a large multiethnic study reported today at the 96th Annual Meeting of the American Association for Cancer Research.

20 Apr 2005

Why people get drowsy and fall asleep, and how caffeine blocks that process

When cells in a certain part of the brain become overworked, a compound in the brain kicks in, telling them to shut down. This causes people to become drowsy and fall asleep. Alter that natural process by adding coffee or tea, and the brain compound – called adenosine – is blocked, and people stay awake.

20 Apr 2005

Antibiotic treatment does not reduce risk of secondary cardiac events

Taking antibiotics weekly for one year does not reduce the risk of a heart attack or other cardiac event for patients with stable coronary artery disease, according to a study funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health. It is published in the April 21, 2005, edition of the New England Journal of Medicine.

20 Apr 2005

First study of mercury and cognitive function in urban, U.S. adults

Although the omega-3 fatty acids found in fish are well known for their health benefits, many fish are also the primary source of mercury in the general population.

20 Apr 2005

Enhancing the resources available to low-income, urban African American women could protect against poor health and symptoms of depression

Enhancing the resources available to low-income, urban African American women to make their neighborhoods safer could protect them against poor health and symptoms of depression, says Tulane University School of Public Health and Tropical Medicine community health researcher Adam Becker.

20 Apr 2005

New study challenges CDC's 400,000 obesity deaths figure

A new study by researchers at the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) published in JAMA concludes that obesity kills 112,000 Americans each year -- a dramatic decrease from an admittedly flawed study published last year by the CDC.

20 Apr 2005