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Cannabis-based medicines given in a highly-controlled clinical environment unexpectedly lead to strong psychotic effects

Volunteers taking cannabis-based therapeutic drugs as part of a controlled trial, which had been approved by an ethics board as safe for the subjects, experienced psychotic effects just as strong as if they had smoked cannabis. These findings, highly unexpected in such a controlled environment, are published today in the peer-reviewed, Open Access journal BMC Psychiatry.

3 Apr 2005

New methods for training eyes to pinpoint

A new study suggests there may be a better way to sharpen the eyes of radiologists, military pilots and other professionals for whom identifying objects or patterns in a monitor or visual display – often quickly and with pinpoint accuracy – is a critical part of the job.

3 Apr 2005

Radiation for prostate cancer doubles the risk of developing rectal cancer

Men who undergo radiation for prostate cancer have nearly double the risk of developing rectal cancer when compared to men who opt to have surgery to treat prostate cancer, according to a study published today in the American Gastroenterological Association (AGA) journal Gastroenterology.

3 Apr 2005

Stress may enhance the body's ability to fight the flu

Short bouts of intense social stress improved the ability in the mice to recover from the flu. The stress apparently did so by substantially boosting the production of specialized immune cells that fought the virus.

3 Apr 2005

Simvastatin linked to protection against endothelial dysfunction in diabetic rats

Almost two years ago, the diabetes arm of the Heart Protection Study, the largest-ever study using a cholesterol-lowering medication, found that diabetics who took a daily dose of the statin drug simvastatin over five years reduced the risk of a first nonlethal heart attack by 37 percent and risk of a first nonfatal or fatal stroke by 24 percent, regardless of their cholesterol or glucose levels.

3 Apr 2005

Directly observed therapy effective against drug resistant tuberculosis

Directly observed therapy (DOTS) - the main strategy for tuberculosis control - can rapidly reduce the transmission and incidence of the drug resistant form of the disease, concludes a study published in this week’s issue of The Lancet.

3 Apr 2005

Sexual behaviour alone doesn’t explain the differences in STIs among ethnic groups

Patterns of sexual lifestyles and sexually transmitted infections (STI) vary among ethnic groups in Great Britain, concludes a study in this week’s issue of The Lancet.

3 Apr 2005

Not enough evidence that multivitamins prevent infections in the elderly

Role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomised controlled trials BMJ Online First.

3 Apr 2005

Aspirin safer than Warfarin for treating blocked arteries

National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), have shown for the first time that aspirin works as well as warfarin in reducing blood clotting. Until now doctors have lacked good evidence for choosing one therapy over the other.

30 Mar 2005

First North American trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer

Today, a new clinical trial evaluating a novel approach to breast cancer prevention launched in the United States and Canada. Called the ExCel research study, this is the first North American clinical trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer.

30 Mar 2005

High-rise homes have the highest levels of cockroach allergens

Roaches like to live high in the sky in places like Chicago, New York City and the Bronx, according to a recent study in the Journal of Allergy and Clinical Immunology. The study, conducted by an allergist affiliated with Children's Medical Center Dallas, found high-rise homes in Northeastern cities had the highest levels of cockroach allergens -- leading to a higher incidence of asthmatic episodes.

30 Mar 2005

Conventional wisdom could be wrong in primary care

A study by Mark Hall, J.D., professor of law and public health sciences at Wake Forest University Baptist Medical Centre, is suggesting that conventional wisdom could be wrong in that primary care doctors who coordinate the care of their patients by specialists may actually have lower liability risk than primary care doctors who do not attempt care coordination.

29 Mar 2005

Coordinating care of chronically ill patients does not increase liability

Conventional wisdom is wrong: primary care doctors who coordinate the care of their patients by specialists may actually have lower liability risk than primary care doctors who do not attempt care coordination.

29 Mar 2005

Study links colic, maternal depression to family problems

Some families with new babies face excessive infant crying, or colic. And some new mothers go through maternal post-partum depression (PPD) following childbirth. Neither situation is considered healthy, but a recent study published in the Infant Mental Health Journal has found that the combined impact of colic and PPD can have a highly toxic outcome. Researchers have linked colicky babies and maternal depression to decrease in overall family functioning.

29 Mar 2005

Role of uric acid in heart disease

In this month's premier open access medical journal PLoS Medicine, John Danesh and colleagues from the University of Cambridge, along with investigators from the Icelandic Heart Association, report the single largest prospective study addressing the role of uric acid in heart disease.

29 Mar 2005

An overconfident physician will not seek help or may ignore help that is offered

Physicians' often do not have correct perceptions of the accuracy of their diagnoses at the time they make them, and in significant numbers of cases they may be overconfident - wrong when they believe they are right; or underconfident - right when they believe they are wrong--about their diagnostic assessments, according to a University of Pittsburgh study.

29 Mar 2005

Pcsk9 gene - new target for cholesterol-lowering drugs

Mice lacking a key protein involved in cholesterol regulation have low-density lipoprotein, or "bad" cholesterol, levels more than 50 percent lower than normal mice, and researchers suggest that inhibiting the same protein in humans could lead to new cholesterol-lowering drugs.

29 Mar 2005

Depression and anxiety affects one in two breast cancer patients

Almost half of all women with early breast cancer experience depression or anxiety in their first year after diagnosis, reveals a study published in the current issue of the British Medical Journal.

29 Mar 2005

Girls more active with sports they enjoy

The more enjoyable a physical education program can be made for adolescent girls, the more likely they are to be physically active, according to new research in the March issue of Medicine & Science in Sports & Exercise®, the official journal of the American College of Sports Medicine (ACSM).

29 Mar 2005

Academic medical centres need to monitor advertising

Similar advertising practices by pharmaceutical companies have been criticized for creating demand for services and failing to present balanced information, but academic medical centres have not been criticised, says Dr. Robin Larson, instructor in medicine at DAMS and lead author of the study.

28 Mar 2005