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ViroLogic and AstraZeneca to conduct Iressa biomarker study

ViroLogic announced today that it had entered into an agreement with AstraZeneca to conduct a cancer biomarker study with application to Iressa, AstraZeneca's selective epidermal growth factor receptor kinase inhibitor.

7 Mar 2005

Studies find Aspirin resistance in up to 27% of Aspirin users

While aspirin remains a crucial and cost-effective therapy for the prevention and management of cardiovascular diseases, research suggests that a significant percentage of the 25 million Americans on a chronic aspirin regimen are "aspirin resistant," or do not achieve sufficient antiplatelet effects from aspirin.

7 Mar 2005

Who would have thought we needed to study men for a cancer that targets women?

Who would have thought we needed to study men for a cancer that targets women? Anna Giuliano, Ph.D., at the H. Lee Moffitt Cancer Center & Research Institute, is doing just that in an investigation concerning the human papillomavirus (HPV).

7 Mar 2005

Study shows that African American children with asthma have significantly higher levels of cotinine

A new study may help explain why African American children suffer disproportionately from tobacco-related illness.

6 Mar 2005

St. John's wort increases effectiveness of Plavix

The widely used herbal remedy St. John's wort appears to amplify the action of the popular blood-thinning drug clopidogrel, sold as Plavix, a small new clinical study finds.

6 Mar 2005

MRI useful in assessment of suspected breast cancer patients

If a mammogram or sonogram suggests that a woman has breast cancer, an MRI should be done to help determine whether there actually is a cancer and if so, what are the woman’s best treatment options, a new study shows.

6 Mar 2005

New therapeutic targets in liver diseases

Many patients with liver diseases often encounter difficulties with therapy and ultimately require liver transplant to survive. Since many acute and chronic liver diseases are driven by immune-mediated mechanisms, there is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage.

6 Mar 2005

Phase 1 clinical trials have greater response rates than had been previously believed

A new study by the Department of Clinical Bioethics at the National Institutes of Health, has found that twice as many cancer patients testing medications in early, phase 1 clinical trials have positive response rates than had been previously believed.

3 Mar 2005

Autism and MMR, no link found

Fears that the triple vaccine for measles, mumps and rubella could cause autism were first raised in 1998 by a gastroenterologist, Andrew Wakefield, his research has been largely discredited. and any lingering doubt of a link between autism and MMR has been completely dispelled by a new study that found withdrawing the vaccine did nothing to slow the rise in children diagnosed with the condition.

3 Mar 2005

Emergency room intervention for problem drinkers in ten minutes

Emergency room practitioners can be successfully trained in two hours to counsel problem drinkers in a 10-minute intervention, according to a study by Yale researchers in Academic Emergency Medicine.

3 Mar 2005

Freezing tumors is an effective way to treat a cancer patient's pain

The study, which appears in the March 2005 issue of the American Journal of Roentgenology, found that cryoablation relieved the pain of four patients who had very advanced disease.

3 Mar 2005

Medical interventions during pregnancy and childbirth may not be the best way to improve newborn survival

In Brazil neonatal mortality declined in the 1980’s but rates have virtually remained unchanged since the 1990’s. Fernando Barros (Hospital de Clinicas, Montevideo, Uruguay) and colleagues studied births in 1992, 1993, and 2004 in the Brazilian city of Pelotas. They found that important changes in maternal characteristics occurred over the 22 years covered by the study.

3 Mar 2005

Increases in macronutrient consumption during pregnancy can lead to increased birthweight

Giving pregnant women in the developing world a daily supplement containing 10 vitamins and five minerals could help increase the birthweight of their babies, concludes a study published online by The Lancet.

3 Mar 2005

Massage with sunflower seed oil helps low birth weight babies

Massaging low birth weight babies with sunflower seed oil is a low cost intervention that can protect them from infections, concludes a study published online by The Lancet.

3 Mar 2005

Possible errors in treatment of depression

A new study documenting the treatment of late-life depression by Canadian health professionals will be presented today at the American Psychosomatic Society Annual Meeting in Vancouver, Canada.

3 Mar 2005

Smoking prevention programs in junior high or high school have little influence on whether teens choose to light up

"Our study shows there is little evidence to suggest that existing school-based smoking prevention programs produce long-term reductions in smoking prevalence among youth," says the study's first author, Sarah Wiehe, M.D., M.P.H., assistant professor of pediatrics, Division of Children's Health Services Research at the Indiana University School of Medicine.

3 Mar 2005

Gender discrepancies in who gets bypass surgery

A study published in the latest issue of Psychology of Women Quarterly found gender biases and long-standing gender discrepancies in who gets bypass surgery. In 1988, twelve percent of female patients who had profiles consistent with the bypass surgery received it-- as compared to twenty-four percent of men.

3 Mar 2005

Future research should lead to better layout of work and equipment for orthodontists and all other dental workers

Gap-toothed youngsters may not be the only ones who are a little sore when they leave the orthodontist's office. While they sport tight braces on their teeth, their doctors may be nursing tight, aching backs, according to a study from the University of Alberta.

3 Mar 2005

MRI better than current standard of practice in assessing neoadjuvant chemotherapy in breast cancer patients

More breast cancer patients with large palpable tumors are now undergoing chemotherapy before surgery in an effort to reduce the size of their tumor, and MRI is the best way to predict if the chemotherapy is working, preliminary results of a study show. If the chemotherapy is successful, then the woman may be able to undergo breast-conservation surgery rather than a mastectomy.

3 Mar 2005

Inherited traits and tumor mutations affect response to treatment of leukemia

The outcome of chemotherapy treatment for acute lymphoblastic leukemia (ALL) depends not only on the acquired genetic make-up of the leukemic cells, but on genes that children inherit from their parents. This study, from investigators at St. Jude Children's Research Hospital, is published in the online edition of Blood.

3 Mar 2005