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Personal benefit, helping others motivate clinical trial participants

Most HIV-infected individuals participating in a clinical trial hope to benefit personally from the research but also understand they are contributing to society, according to a report in the June 23 issue of Archives of Internal Medicine.

24 Jun 2008

Subtle but detectable neurological abnormalities appear to predict risk of death in older individuals

Subtle but clinically detectable neurological abnormalities, such as reduced reflexes and an unstable posture, may be associated with the risk of death and stroke in otherwise healthy older adults, according to a report in the June 23 issue of Archives of Internal Medicine.

24 Jun 2008

Nearly one in five patients experiences chest pain one year after having a heart attack

One of the main goals of in-hospital treatment and outpatient care after heart attack is to relieve angina (or episodic chest pain), according to background information in the article. The prevalence and treatment of chest pain one year after heart attack are largely unknown.

24 Jun 2008

Racial disparities in colorectal cancer screening rates

Blacks and Hispanics appear less likely to undergo colorectal cancer screening than whites because of socioeconomic, health care access and language barriers, according to a report in the June 23 issue of Archives of Internal Medicine. However, other factors may contribute to screening disparities experienced by Asians.

24 Jun 2008

General anesthesia can increase post-surgical pain

The general anesthesia that puts patients into unconscious sleep so they do not feel surgical pain can increase the discomfort they feel once they wake up, say researchers from Georgetown University Medical Center.

24 Jun 2008

Neurological assessment of older adults should become routine examinations

Standard neurological exams of older adults are good predictors of future brain health and quality of life. These tests should become part of the physician's routine examination of older adults say faculty from the Indiana University Center for Aging Research in an editorial in the June 23, 2008 issue of the Archives of Internal Medicine.

24 Jun 2008

Simple ultrasound exam may predict osteoporosis risk

An ultrasound exam of the heel may be able to predict if a woman is at heightened risk for fractures due to osteoporosis, according to a new multicenter study being published in the July issue of the journal Radiology.

24 Jun 2008

Automated magnetic resonance imaging technique assists in earlier Alzheimer's diagnosis

An automated system for measuring brain tissue with magnetic resonance imaging (MRI) can help physicians more accurately diagnose Alzheimer's disease at an earlier stage according to a new study published in the July issue of the journal Radiology.

24 Jun 2008

Drug rapamycin reverses mental retardation caused by tuberous sclerosis complex

UCLA researchers discovered that an FDA-approved drug reverses the brain dysfunction inflicted by a genetic disease called tuberous sclerosis complex (TSC). Because half of TSC patients also suffer from autism, the findings offer new hope for addressing learning disorders due to autism. Nature Medicine publishes the findings in its online June 22 edition.

23 Jun 2008

Lower blood levels of vitamin D linked to increased heart problems

Individuals with lower blood levels of vitamin D appear to have an increased risk of death overall and from cardiovascular causes, according to a report in the June 23 issue of Archives of Internal Medicine.

23 Jun 2008

Study: Outreach and internal navigation program on breast cancer diagnosis in an urban cancer center with a large African-American population

A new study indicates that community education outreach and internal navigation programs lead to a significant shift in stage at diagnosis of breast cancer among African American women, with a doubling in the proportion of cases caught at the earliest stage and a nearly reciprocal drop in the proportion of cancers at most advanced stage.

23 Jun 2008

The impact of socioeconomic status on survival after cancer in the United States

Cancer patients with low socioeconomic status (SES) have more advanced cancers at diagnosis, receive less aggressive treatment, and have a higher risk of dying in the five years following cancer diagnosis, according to a new study.

23 Jun 2008

Evidence for an increased cancer risk following the use of radioactive Radium-224 in the therapy for Ankylosing Spondylitis

In the course of an epidemiological study, scientists of the Institute of Radiation Biology of the Helmholtz Zentrum München - German Research Center for Environmental Health - have established an unfavourable benefit-risk-ratio for ankylosing spondylitis patients treated with Radium-224 therapy (Rheumatology 2008; 47: 855-59).

23 Jun 2008

Management of hypertension immediately after stroke

A research project at the University of Leicester in conjunction with the University of East Anglia, indicates that early reduction of high blood pressure following stroke is feasible and safe, and both Labetalol & Lisinopril were found to be suitable a medications for this purpose.

23 Jun 2008

Canopus BioPharma enters phase II clinical trials with CB1400

Canopus BioPharma, Inc. has announced that the South African Medicines Control Council has granted approval for a Phase II study in 30 cancer patients evaluating the protective effect of CB1400 on the gastrointestional tract from radiation-induced mucositis. This new trial is an important step forward in the development of CB1400 as a novel, preventative, anti-mucositis agent.

23 Jun 2008