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First clinical trial data of a fully bioabsorbable drug-eluting stent

Data published today in The Lancet from ABSORB, the world's first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-treatment of a diseased lesion), and a low (3.3 percent) rate of major adverse cardiac events (MACE) in 30 patients out to one year.

14 Mar 2008

How diabetes drives atherosclerosis

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

14 Mar 2008

Study explains fundamental process of tumor growth

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

14 Mar 2008

Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?

Surgery is the only curative treatment in patients with bile duct cancer.

14 Mar 2008

Artificial butter chemical acetyl harmful to lungs

A new study shows that exposure to a chemical called diacetyl, a component of artificial butter flavoring, can be harmful to the nose and airways of mice.

14 Mar 2008

Study confirms link between colds and ear infections

A new five-year study at the University of Texas Medical Branch at Galveston confirms the suspected close link between the two most common diseases of young children: colds and ear infections.

14 Mar 2008

Giving up smoking during pregnancy boosts chances of easygoing child

Giving up smoking during pregnancy may boost the chances of giving birth to an easy going child, indicates research in the Journal of Epidemiology and Community Health.

14 Mar 2008

Psychological intervention reduces postembolization pain

Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy.

14 Mar 2008

Prescribing costs increase dramatically when people reach 65

Prescribing costs increase dramatically when people reach 65, according to a detailed analysis of more than five million patients published in the March issue of the British Journal of Clinical Pharmacology.

14 Mar 2008

Colorectal cancer screening increasing among U.S. adults

The percentage of U.S. adults aged 50 years and older getting screened for colorectal cancer is increasing according to a study released by the Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008

New drug protects nerve cells from damage in mice

Multiple sclerosis (MS) is a chronic inflammatory disease of the brain and spinal cord. Individuals with MS develop progressive neurological disability, and this is thought to be caused by degradation of the nerve cells.

14 Mar 2008

MGH initiates trial to reverse type 1 diabetes

Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes.

14 Mar 2008

Study shows Parkinson's disease drug dopamine might work in cancer patients

A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson's disease and other illnesses, also might work in cancer patients.

14 Mar 2008

Low cost tactics improve medication use after heart attack

Direct-to-patient communication about the importance of continuing prescription drug treatment after a heart attack is a simple, low-cost way to increase the likelihood of patients adhering to life saving therapies at least four out of every five days.

14 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

14 Mar 2008

Lilly and Transition Therapeutics announce licensing and collaboration agreement

Eli Lilly and Company and Transition Therapeutics Inc. has announced that the two companies have entered into a licensing and collaboration agreement granting Lilly exclusive worldwide rights to develop and commercialize Transition's gastrin based therapies, including the lead compound TT-223, which is currently in early Phase II testing.

14 Mar 2008

Damaged veins heal faster with heparin treatment, laboratory study finds

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

14 Mar 2008

Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma

Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma (ESCC). There are synergetic interactions among alcohol drinking and ALDH2, ADH1B, CYP2E1 genotypes.

14 Mar 2008

A tumor of the pancreas mimicked by colonic duplication

A case of cystic colonic duplication in an adult mimicked a tumor of the pancreas and the diagnosis was established by histopathological examination of the resected specimen after distal pancreatectomy.

14 Mar 2008