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Low dose inhaled corticosteroids improve lung function in mild asthma patients

A study by the Woolcock Institute of Medical Research in Sydney is the first to demonstrate that in patients with very mild or well-controlled asthma, regular treatment with low dose ICS leads to significantly better day-to-day lung function.

11 Mar 2008

Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers

Recurrent low-grade serous carcinoma, a rare type of ovarian cancer, is less sensitive to chemotherapy and therefore more difficult to treat than more common high-grade ovarian cancers, according to researchers from The University of Texas M. D. Anderson Cancer Center.

11 Mar 2008

Novel brain cancer drug HhAntag for children may damage bones

A novel drug that fully eliminated brain tumors from mice in a dramatic 2004 study has shown a darker side - causing permanent bone damage in younger mice.

11 Mar 2008

Post-stroke clot-busting therapy beneficial for patients on aspirin

Patients given a clot-busting drug following stroke appear to have better outcomes if they were already taking anti-platelet medications, despite an apparent increased risk for bleeding in the brain, according to an article posted online that will appear in the May 2008 print issue of Archives of Neurology.

11 Mar 2008

Survival rates for patients for with non-Hodgkin lymphoma improved over past decade

Five- and 10-year survival rates for patients with non-Hodgkin lymphoma appear to have increased from the 1990s to the early 21st century, according to a report in the March 10 issue of Archives of Internal Medicine.

11 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008

Offspring of parents who both have Alzheimer's disease may be more likely to develop the illness

Adult-age offspring of parents who have both been diagnosed with Alzheimer's disease appear to have an increased risk of developing the disease compared with the general population, according to a report in the March issue of Archives of Neurology.

11 Mar 2008

Nasal polyps from analgesics

If a patient develops respiratory problems after taking analgesics, this indicates that the active substances are poorly tolerated.

11 Mar 2008

Observational study of severe osteoporosis

Women who do not comply with treatment instructions for osteoporosis or who do not respond to treatment are more likely to suffer further fractures, which seriously affects their quality of life.

11 Mar 2008

Study aims to improve treatment for children born with heart defects

Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study.

11 Mar 2008

Low levels of PYY hormone indicate higher risk of developing type 2 diabetes and obesity

It may soon be possible to take a simple blood test and predict whether or not someone has low levels of a particular molecule, predisposing them to the development of Type 2 diabetes.

11 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

11 Mar 2008

Late treatment with letrozole (Femara) can reduce breast cancer recurrence risk

Treatment with the aromatase inhibitor letrozole (Femara) can reduce the risk of breast cancer recurrence even when initiated one to seven years after a course of tamoxifen therapy.

11 Mar 2008

Kidney cancer surgery often determined by surgeons' practice style, not medical factors

A new study reveals that the type of surgery a patient with kidney cancer receives depends more on the surgeon's preference than on the patient's tumor size, demographic characteristics, or general medical health.

11 Mar 2008

Investigator attendance at review board reviews: hindrance or help?

Inviting researchers to attend institutional review board sessions designed to approve these same investigators' requests to conduct research involving human subjects doesn't seem to affect the efficiency of the process one way or the other, a new study led by Johns Hopkins bioethicists suggests.

11 Mar 2008

Pesticides and nerve agents explain health problems in Persian Gulf war veterans

A study by researchers at the University of California, San Diego School of Medicine shows there is increasing evidence that high rates of illness in Persian Gulf War Veterans can be explained, in part, by exposure to certain chemicals, including pesticides and nerve agents.

11 Mar 2008

Glaucoma associated with increased risk of cardiovascular death in black patients

Black patients with diagnosed and treated glaucoma and those with high pressure in their eyes appear to have an increased risk of death from cardiovascular causes, according to a report in the March issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Mar 2008

Gender bias may affect care of people with osteoarthritis

Unconscious prejudices among doctors may explain why women complaining of knee pain are less likely than men to be recommended for total knee replacement surgery, a study in the current issue of the Canadian Medical Association Journal suggests.

11 Mar 2008

Femara helps protect against return of breast cancer after completing Tamoxifen therapy

Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole tablets) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

11 Mar 2008

Just one hour of exposure to diesel exhaust fumes induces a stress response in brain

If the smell of diesel exhaust isn't enough to make you avoid getting a lungful, new research now shows that even a short exposure to the fumes can affect your brain.

11 Mar 2008

Drug Trial News

Low dose inhaled corticosteroids improve lung function in mild asthma patients

Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers

Novel brain cancer drug HhAntag for children may damage bones

Post-stroke clot-busting therapy beneficial for patients on aspirin

Survival rates for patients for with non-Hodgkin lymphoma improved over past decade

Long-term effects of synthetic progestins cause for concern

Offspring of parents who both have Alzheimer's disease may be more likely to develop the illness

Nasal polyps from analgesics

Observational study of severe osteoporosis

Study aims to improve treatment for children born with heart defects

Low levels of PYY hormone indicate higher risk of developing type 2 diabetes and obesity

Long-term muscle improvements shown in gene therapy study in mice

Late treatment with letrozole (Femara) can reduce breast cancer recurrence risk

Kidney cancer surgery often determined by surgeons' practice style, not medical factors

Investigator attendance at review board reviews: hindrance or help?

Pesticides and nerve agents explain health problems in Persian Gulf war veterans

Glaucoma associated with increased risk of cardiovascular death in black patients

Gender bias may affect care of people with osteoarthritis

Femara helps protect against return of breast cancer after completing Tamoxifen therapy

Just one hour of exposure to diesel exhaust fumes induces a stress response in brain

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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