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Study looks at breast-cancer drug called Abraxane for bladder cancer

As many as half of patients with superficial bladder cancer do not respond to the standard first-line chemotherapy placed into the bladder, according to current multi-center outcomes data.

27 Feb 2008

Risks of CVD for COX-2 inhibitors lower than previously reported

In an article published in the March issue of the Journal of Cardiovascular Pharmacology and Therapeutics, researchers from Florida Atlantic University (FAU) assess the totality of evidence, including strengths and limitations of different types of evidence contributing to the debate about cardiovascular disease (CVD) risks of cyclooxygenase-2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

27 Feb 2008

New radiation therapy standards needed

Modern radiation techniques result in substantial variation between the prescribed dose and the actual dose of radiation delivered to the tumor, according to a study published online February 26 in the Journal of the National Cancer Institute.

27 Feb 2008

Minimally invasive fibroid treatment fares well in multicenter trial

A new multicenter trial found that uterine artery embolization (UAE) is a good alternative to hysterectomy in women with symptomatic fibroids.

27 Feb 2008

IRIS International completes study of 85 post-prostatectomy patients using investigational NADiA PSA assay

IRIS International Inc. has announced that its Iris Molecular Diagnostics (IMD) group has successfully completed a retrospective study of stored leftover serum of 85 post-prostatectomy patients, men who had their prostate removed due to prostate cancer, using its investigational NADiA (Nucleic Acid Detection ImmunoAssay) PSA Assay.

27 Feb 2008

Faster chemo technique increases survival in children with neuroblastoma

Chemotherapy given with shorter intervals between treatments than conventional chemotherapy increases survival rates by two thirds in children with high-risk neuroblastoma , according to a study published in the Lancet Oncology * today (Tuesday).

27 Feb 2008

Facial asymmetry persists despite surgery to correct congenital deformity

Adults and teens that underwent surgery as infants to correct a congenital condition that causes the forehead and face to appear uneven still have a degree of facial asymmetry years later, according to new research led by a Hasbro Children's Hospital surgeon.

27 Feb 2008

Drug for anemic cancer patients raises risk of death

Millions of cancer patients take drugs to boost their red blood cells and health when they become anemic after chemotherapy.

27 Feb 2008

Brain stress system shows promise as a new therapeutic target for alcoholism

A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).

27 Feb 2008

Anemia drug linked to blood clots, death in cancer patients

Treating anemia with a class of drugs known as erythropoiesis-stimulating agents (ESAs) is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs) and death among patients with cancer, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Adult-onset obesity seen in mice when gene ubiquitin disrupted

Texas and California scientists who disrupted one type of the gene ubiquitin (Ubb) in mice observed neuronal death in the hypothalamus, impaired control of energy balance and adult-onset obesity in the rodents.

27 Feb 2008

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases

A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Adding therapy helps adolescents with depression not responding to SSRIs

For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications, according to a study in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Tenofovir gel safe for daily use over an extended period

A vaginal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel.

27 Feb 2008

Cognitive impairment among older Americans is declining

Rates of cognitive impairment among older Americans are on the decline, according to a new study supported by the National Institutes of Health (NIH) comparing the cognitive health of older people in 1993 and 2002.

27 Feb 2008

Links between obesity, carbs and esophageal cancer

Cases of esophageal cancer (adenocarcinoma) in the U.S. have risen in recent decades from 300,000 cases in 1973 to 2.1 million in 2001 at age-adjusted rates.

27 Feb 2008

Step-parents influence teenage smoking behaviour

Smoking by a non-biological parent is as influential as smoking by biological parents in determining whether their teenager smokes, reveal the results of a Cancer Research UK study published in the journal Addiction.

27 Feb 2008

18-24 year olds have highest approval rating for cosmetic surgery

In a new study commissioned by the American Society for Aesthetic Plastic Surgery (ASAPS), men and women ages 18-24 had the highest approval rating for cosmetic surgery.

27 Feb 2008

Number of Americans living with heart failure has increased

The number of elderly individuals newly diagnosed with heart failure has declined during the past ten years, but the number of those living with the condition has increased, according to a report in the February 25 issue of Archives of Internal Medicine.

26 Feb 2008

Mechanism of blood clot elasticity revealed in high definition

Blood clots can save lives, staunching blood loss after injury, but they can also kill. Let loose in the bloodstream, a clot can cause a heart attack, stroke or pulmonary embolism.

26 Feb 2008