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Australian gene test opens door to personalised care

Australian researchers have led a study published in the New England Journal of Medicine that shows a simple blood test can allow doctors to predict which HIV patients will have a side effect, known as a hypersensitivity reaction, to a particular medication before it is prescribed.

6 Feb 2008

People with manic depression have a distinct chemical signature in their brains

People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause.

5 Feb 2008

PDAs push older adults into increasing their physical activity levels

Today's younger generation may reckon that "ne'er the twain shall meet" where technology and their elders are concerned. However, ongoing research by Abby King, PhD, professor of health research and policy and of medicine at the Stanford Prevention Research Center, appears to be gradually dispelling that notion.

5 Feb 2008

Study shows that a key protein appears to enable spread of melanoma to the small intestine

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center has shown that a receptor protein found on melanoma cells appears to facilitate the disease's spread to the small intestine.

5 Feb 2008

Experimental drug shows promise for cystic fibrosis

An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).

5 Feb 2008

Taking more than one NSAID may lead to complications

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat arthritis, which affects one-third of all adults.

5 Feb 2008

Study finds widespread vitamin and mineral use among cancer survivors, although benefits of such use remain unclear

Use of vitamin and mineral supplements among cancer survivors is widespread, despite inconclusive evidence that such use is beneficial, according to a comprehensive review of scientific literature conducted by researchers at Fred Hutchinson Cancer Research Center and published Feb. 1 in the Journal of Clinical Oncology.

5 Feb 2008

Parental drinking and parenting practices influence adolescent drinking

Adolescence is a critical time of development on many different levels, but especially concerning the initiation and escalation of alcohol use. For example, the proportion of American adolescents who regularly drink alcohol roughly doubles during secondary-school years. New findings show that parental drinking both directly influences adolescent drinking, as well as indirectly through adolescent perceptions of parenting, especially monitoring and discipline received.

5 Feb 2008

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

An enhanced version of the Original European Liver Fibrosis panel was found to have good diagnostic accuracy for fibrosis in patients with non-alcoholic fatty liver disease. Conversely, transient elastography was unreliable for detecting cirrhosis in patients with acute liver damage. The studies are published in the February issue of Hepatology, a journal by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The articles are also available online at Wiley Interscience.

5 Feb 2008

Experimental biomarker test beats PSA in detecting prostate cancer

An experimental biomarker test developed by researchers at the University of Michigan more accurately detects prostate cancer than any other screening method currently in use, according to a study published in the February 1 issue of Cancer Research, a journal of the American Association for Cancer Research.

5 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

New vaccine for malaria under trial

Trials are underway, funded by the Wellcome Trust, for a new vaccine to combat the most deadly form of malaria.

5 Feb 2008

Chemists track how amantadine drug changes, blocks flu virus

An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists.

5 Feb 2008

Gene ENPP1 is linked to preterm birth and low birth weight among Hispanic women

Researchers at Yale School of Medicine have found that the gene ENPP1 is linked to preterm birth and low birth weight among Hispanic women.

5 Feb 2008

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder that can cause uncontrolled bleeding.

5 Feb 2008

Changes in narcoleptics' skin, core body temperatures affect their vigilance and sleepiness

In healthy people, both sleepiness and vigilance show a relationship with core body temperature and skin temperature.

5 Feb 2008

Black people die more frequently of severe sepsis that either whites or Hispanics

Blacks have almost double the rate of severe sepsis an overwhelming infection of the bloodstream accompanied by acute organ dysfunction as whites, according to recent research.

5 Feb 2008

Balloon catheter-based sinus surgery radiation exposure very low, safe

A new and increasingly popular type of minimally invasive sinus surgery exposes patients to only "very low" doses of radiation during the procedure, a level considered to be safe, according to a new study published in the February 2008 issue of the journal Otolaryngology - Head and Neck Surgery.

5 Feb 2008

Ascal (calcium carbasalate) not safer than aspirin

Changing prescription of low-dose aspirin into calcium carbasalate (brand name: Ascal) to prevent peptic ulcerations is not useful. Peptic ulcers are evenly distributed among users of calcium carbasalate and aspirin, for secondary prevention of myocardial infarction.

5 Feb 2008

Insomnia patients often denied sleep treatment when they have mental health problems

Patients with insomnia who are diagnosed with accompanying mental health ailments often are not prescribed medication that will help them sleep - which could then make related anxiety or depression worse, new research suggests.

4 Feb 2008

Drug Trial News

Australian gene test opens door to personalised care

People with manic depression have a distinct chemical signature in their brains

PDAs push older adults into increasing their physical activity levels

Study shows that a key protein appears to enable spread of melanoma to the small intestine

Experimental drug shows promise for cystic fibrosis

Taking more than one NSAID may lead to complications

Study finds widespread vitamin and mineral use among cancer survivors, although benefits of such use remain unclear

Parental drinking and parenting practices influence adolescent drinking

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

Experimental biomarker test beats PSA in detecting prostate cancer

Enbrel shown to significantly reduced levels of C-reactive protein

New vaccine for malaria under trial

Chemists track how amantadine drug changes, blocks flu virus

Gene ENPP1 is linked to preterm birth and low birth weight among Hispanic women

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Changes in narcoleptics' skin, core body temperatures affect their vigilance and sleepiness

Black people die more frequently of severe sepsis that either whites or Hispanics

Balloon catheter-based sinus surgery radiation exposure very low, safe

Ascal (calcium carbasalate) not safer than aspirin

Insomnia patients often denied sleep treatment when they have mental health problems

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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