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Prion infection of neurons increases the free cholesterol content in cell membranes

A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases.

12 Feb 2008

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior - also called stereotypies - that is characteristic of autism.

12 Feb 2008

Coronary disease may be on the rise

A Mayo Clinic analysis of two decades of autopsy results shows a long-term decline in the prevalence of coronary disease has ended and the disease may be on the upswing.

12 Feb 2008

White seniors more likely to have signs of future eye disease than black seniors

White individuals older than 65 are more likely than black individuals to have characteristics that indicate they will develop more advanced forms of the eye disease age-related macular degeneration (AMD), according to a report in the February issue of Archives of Ophthalmology.

12 Feb 2008

Most hypertension patients ignore recommended diet

A relatively small proportion of individuals with hypertension (high blood pressure) eat diets that align with government guidelines for controlling the disease, according to a report in the February 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12 Feb 2008

Learning disabilities associated with language problems later in life

Individuals with a neurodegenerative condition affecting language appear more likely to have had a history of learning disabilities than those with other types of dementia or with no cognitive problems, according to a report in the February issue of Archives of Neurology.

12 Feb 2008

Gene therapy protocol at UCSD activates immune system in patients with leukemia

A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.

12 Feb 2008

Oxcarbazepine doesn't prevent migraine

Contrary to some reports, the epilepsy drug oxcarbazepine does not appear to prevent migraine, according to research published in the February 12, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.

12 Feb 2008

Donors' health associated with risk of infection among recipients of corneal transplants

Corneal grafts obtained from donors dying in the hospital or with cancer may be associated with an increased risk of infection for the recipient, according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

12 Feb 2008

Doctors uncertain about approaches to care for heart failure patients

Less than one fourth of physicians specializing in geriatrics, internal or family medicine or cardiology believe they can accurately predict the whether patients with heart failure are at risk of dying, new Saint Louis University research found.

12 Feb 2008

Are patients making clinical decisions?

Doctors are adjusting their bedside manner as better informed patients make ever-increasing demands and expect to be listened to, and fully involved, in clinical decisions that directly affect their care.

12 Feb 2008

Avastin (bevacizumab) damages brain vessels

The cancer drug Avastin (bevacizumab) is used to treat advanced bowel cancer in combination with chemotherapy.

12 Feb 2008

Public smoking ban decreases acute coronary events in Italy

The number of acute coronary events such as heart attack in adults dropped significantly after a smoking ban in public places in Italy, researchers reported in Circulation: Journal of the American Heart Association.

12 Feb 2008

$1-year results of bronchial thermoplasty in refractory asthma$

1-year results of bronchial thermoplasty in refractory asthma

Asthmatx, Inc. has announced the publication of data from the Research in Severe Asthma (RISA) Trial of bronchial thermoplasty in the American Journal of Respiratory and Critical Care Medicine (AJRCCM, 2007; 176:1185-1191).

12 Feb 2008

Staging mock cardiac and respiratory arrests expose weaknesses in hospital emergency response for children

Staging mock cardiac and respiratory arrests - "code" situations in hospital parlance - easily expose common failures in rapid response with CPR and other life-saving care for children and also set up powerful incentives to sharpen emergency skills and move fast to use them, suggests a study from the Johns Hopkins Children's Center.

11 Feb 2008

Mild Alzheimer's sufferers show rapid decline in financial skills over one year

New research from UAB (University of Alabama at Birmingham) shows that patients with mild Alzheimer's disease (AD) have a dramatic decline in their ability to make financial decisions over a one year period.

11 Feb 2008

Allergic-like reactions occur in premedicated patients

Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

11 Feb 2008