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Abdominal obesity predicts heart disease

Abdominal obesity is a strong independent risk factor for heart disease, and using the waist-hip ratio rather than waist measurement alone is a better predictor of heart disease risk among men and women, researchers reported in a study published in Circulation: Journal of the American Heart Association.

10 Dec 2007

Study results from Zolinza (vorinostat) in combination with bortezomib for multiple myeloma trial

Results from two investigational Phase I trials of ZOLINZA (vorinostat) in combination with bortezomib provide preliminary anti-tumor activity in patients with relapsed and/or refractory multiple myeloma.

10 Dec 2007

Vaccine improves event-free survival for leukemia patients

Patients whose immune system responded to a peptide vaccine for leukemia enjoyed a median remission that was more than three times longer than non-responders, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American Society of Hematology.

10 Dec 2007

Psychotherapy useful in treating PTSD in early stages

When treated within a month, survivors of a psychologically traumatic event improved significantly with psychotherapy, according to a new study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

New strategy for developing antidepressants

Researchers may be able to develop an antidepressant which takes effect almost immediately by directly targeting novel molecules in the brain instead of taking a less direct route, which can lead to longer times for medication to take effect, according to a new study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Potential blood test to detect lung cancer

A test for four blood proteins may provide a less-invasive follow-up for patients who have suspicious lesions on chest radiographs or computerized tomography (CT) scans, according to a new study led by Duke University Medical Center researchers.

10 Dec 2007

Brain differences found in adolescents with mental illness

Puberty may have an impact on areas of the brain that contribute to bipolar disorder or schizophrenia in youth, according to a study presented at the annual meeting of the American College of Neuropsychopharmacology (ACNP).

10 Dec 2007

Stable sleep patterns and regular routines may improve outcomes in bipolar disorder

Bipolar disorder, commonly known as manic-depressive disorder, is highly influenced by the circadian system - the body's internal clock - and a specific kind of psychotherapy may help decrease irregularities in the circadian system that can trigger key symptoms of bipolar disorder, according to a study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Possible genetic link between schizophrenia and cancer

A series of studies presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting elucidates evidence that there is a genetic link between schizophrenia and cancer, providing a surprising possible scientific explanation for lower rates of cancer among patients with schizophrenia – despite having poor diets and high rates of smoking – and their parents.

10 Dec 2007

Depression nearly triples the risk of death following a heart attack

...even when accounting for other heart attack risk factors, according to research presented at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depression in the first six months were more than twice as likely to die.

10 Dec 2007

Adrenalectomy shown to benefit those with mild Cushing syndrome

Researchers at UT Southwestern Medical Center have found that patients with a mild form of Cushing syndrome, a metabolic disorder caused by adrenal tumors, demonstrate substantial clinical improvement after adrenalectomy.

10 Dec 2007

Study shows how mutations in the BRCA1 gene lead to breast cancer

An international team of researchers led by Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center and Sweden's Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer.

10 Dec 2007

Brain overgrowth in 1-year-olds linked to development of autism

Brain overgrowth in the latter part of an infant's first year may contribute to the onset of autistic characteristics, according to research presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Neurons in the frontal lobe may be responsible for rational decision-making

You study the menu at a restaurant and decide to order the steak rather than the salmon. But when the waiter tells you about the lobster special, you decide lobster trumps steak. Without reconsidering the salmon, you place your order - all because of a trait called "transitivity."

10 Dec 2007

Multiple myeloma clinical trial shows distinct survival benefit with lower dose of steroids

Results of Eastern Cooperative Oncology Group Phase III clinical trial E4A03, for multiple myeloma, showing significantly better overall survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone, were reported today by S. Vincent Rajkumar, M.D. at the American Society of Hematology's annual meeting.

10 Dec 2007

Effects of diet and physical activity on the possibility of developing lung cancer

By simply eating four or more servings of green salad a week and working in the garden once or twice a week, smokers and nonsmokers alike may be able to substantially reduce the risk of developing lung cancer, say researchers at The University of Texas M. D. Anderson Cancer Center.

10 Dec 2007

Fever may restore nerve cell communications in regions of the autistic brain

The behavior of children with autism may improve during a fever, according to a first-of-kind study, "Behaviors Associated With Fever in Children With Autism Spectrum Disorders," published Nov. 30 in Pediatrics.

10 Dec 2007

Denial of care for HIV+ detainees 'unacceptable,' says AHF

On the heels of the Human Rights Watch report descrying the treatment of HIV-positive immigrant detainees, AIDS Healthcare Foundation (AHF) has criticized the U.S. Department of Homeland Security (DHS) for its callous disregard for the health and well-being of people living with HIV/AIDS in its care.

10 Dec 2007

Nilotinib and Dasatinib show promise as therapy for chronic myelogenous leukemia

Two drugs approved for use as second line therapy for chronic myelogenous leukemia are showing promising results as frontline therapy for newly diagnosed patients in two clinical trials, research teams led by scientists at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.

10 Dec 2007

Antibacterial chemical in bath soaps disrupts hormone activities

A new UC Davis study shows that a common antibacterial chemical added to bath soaps can alter hormonal activity in rats and in human cells in the laboratory - and does so by a previously unreported mechanism.

10 Dec 2007