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Improving outcomes for patients with acute coronary syndrome

Recent changes in the recommended treatments used for patients hospitalized for acute coronary syndromes, such as a heart attack, are associated with reductions in the rates of heart failure, stroke, heart attack and death, according to a study in the May 2 issue of JAMA .

2 May 2007

Diesel exhaust fumes affect bone marrow blood flow

A new study finds that exposure to a chemical component of diesel exhaust particles can compromise the ability of resistance arteries to regulate blood flow to bone marrow.

2 May 2007

Soy consumption and weight loss

Research shows that when soy consumption goes up, weight goes down.

2 May 2007

Higher calcium and vitamin D intake linked to brain lesions in seniors

Elderly men and women who consumed higher levels of calcium and vitamin D are significantly more likely to have greater volumes of brain lesions, regions of damage that can increase risk of cognitive impairment, dementia, depression and stroke.

2 May 2007

Efforts to standardize heart care are working

People who suffer a heart attack or severe chest pain today are much less likely to die, or to experience long-lasting effects, than their counterparts even a few years ago, according to a new international study in the May 3 issue of the Journal of the American Medical Association.

2 May 2007

Gender, ethnic differences may hamper eating disorder diagnosis

Eating disorders may be overlooked in some groups - boys and some ethnicities - by physicians accustomed to diagnosing the condition in white teenage girls, say researchers at Lucile Packard Children's Hospital and the Stanford University School of Medicine.

2 May 2007

Revolutionary treatment for blindness

The first clinical trial to test a revolutionary treatment for blindness in children has been announced by researchers at UCL (University College London).

2 May 2007

Spherix starts phase 3 clinical trial of treatment for type 2 diabetes

Spherix Incorporated has announced that it has begun its Phase 3 clinical trial of Naturlose as a treatment for Type 2 diabetes.

2 May 2007

Sleep deprivation can adversely affect a person's decision-making

Gambling is a risky activity that can potentially result in the loss of a significant amount of money.

2 May 2007

Consuming lower-calorie soup a way to reduce food intake

Eating low-calorie soup before a meal can help cut back on how much food and calories you eat at the meal, a new Penn State study shows. Results show that when participants in the study ate a first course of soup before a lunch entree, they reduced their total calorie intake at lunch (soup + entr'e) by 20 percent, compared to when they did not eat soup.

2 May 2007

Seniors are being stereotyped as grouchy

A study of caregivers of Alzheimer's patients and non-caregivers done by the University of Alberta in Edmonton, Canada revealed that seniors are being stereotyped as grouchy, inflexible to change, and mostly living in nursing homes, when the opposite is true.

2 May 2007

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

In a study of children with cystic fibrosis, French researchers found evidence of very early onset defective bone mineralization in the lumbar spine that was not caused by either nutritional status or lung disease.

2 May 2007

Adalimumab shows potential for Crohn's disease

A study led by Mayo Clinic found that adalimumab (HUMIRA) is an effective treatment for adults with Crohn's disease who do not respond to infliximab (REMICADE) therapy.

2 May 2007

Rituximab reduces disease activity in multiple sclerosis

A new drug under investigation shows a reduction in disease activity in multiple sclerosis (MS), according to two studies that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston. The drug reduced disease activity as indicated by MRI scans.

2 May 2007

Sirion Therapeutics starts phase III clinical trials of pipeline compounds

Sirion Therapeutics has announced that it has initiated new phase III clinical programs for two of its pipeline compounds, ST-601 (difluprednate) and ST-603 (cyclosporine).

2 May 2007

Exposure to secondhand tobacco smoke increases the risk of developing dementia

Based on preliminary results, the study authors found that elderly people with high lifetime exposure to secondhand smoke were approximately 30 percent more likely to develop dementia than those with no lifetime secondhand smoke exposure.April 28, May 5, 2007.

2 May 2007

Wrapping version of Gleevec fights drug-resistant cancer

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug Gleevec? is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area.

2 May 2007

Levosimendan compared to dobutamine for decompensated heart failure

The drug levosimendan did not improve survival for patients with decompensated heart failure when compared with a more widely-used treatment for this condition, dobutamine, according to a study in the May 2 issue of JAMA.

2 May 2007

Unstable leukemia stem cells may predispose patients to drug resistance

The BCR-ABL gene in chronic myeloid leukemia stem cells has a tendency to quickly mutate, and this may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute.

2 May 2007

Web-based disease management program improves outcomes for low-income black students

Low-income African-American high school students with asthma who participated in a specially-designed, web-based disease management program reported fewer days and nights with symptoms, fewer school days missed, fewer days of restricted activity, and less hospitalization for asthma during a 12-month follow-up period, as compared to non-participating asthmatic students.

2 May 2007