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Lactate instead of glucose after traumatic brain injury

The chemical lactate has gotten a bad rap. Conventional wisdom considered it to be little more than the bane of runners and other athletes, causing stiff muscles and fatigue, and the "sour" in sour milk. It turns out that view may have been too narrow.

15 Apr 2007

Study on accident related smoke inhalation shows most effected to be non-smokers

New research at Rhode Island Hospital studied the chronic effects of smoke inhalation by examining the lungs of 21 survivors of The Station fire (February 20, 2003).

15 Apr 2007

Men and women show different patterns of brain activity when viewing sexual stimuli

A study funded by the Atlanta-based Center for Behavioral Neuroscience (CBN) analyzed the viewing patterns of men and women looking at sexual photographs, and the result was not what one typically might expect.

15 Apr 2007

Gleevec available to patients in post-surgical GIST study

Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.

15 Apr 2007

Monitoring chronic heart failure patients' health by phone helps

Monitoring patients' health by phone can make a real difference to people with chronic heart failure, according to a study published on bmj.com.

15 Apr 2007

Gleevec shows great promise in preventing cancer recurrence

Gleevec, a pill developed in conjunction with the Oregon Health & Science University Cancer Institute is again showing excellent results in preventing a cancer recurrence.

15 Apr 2007

Transplant patients suffering from anemia have a greater mortality rate

According to a new study in American Journal of Transplantation, kidney transplant patients suffering from anemia, a treatable blood deficiency, are more likely to die or suffer from organ failure than other transplant recipients.

15 Apr 2007

People with two copies of a particular gene have a 70% higher risk of being obese

Scientists have identified the most clear genetic link yet to obesity in the general population as part of a major study of diseases funded by the Wellcome Trust, the UK's largest medical research charity.

15 Apr 2007

Nationwide survey of state Medicaid programs on "pay-for-performance" practices

In the first published nationwide survey of state Medicaid programs on “pay-for-performance” practices, more than half of all programs state that they provide financial incentives to health care providers for better quality care.

15 Apr 2007

Intarcia Therapeutics announces results from study of injectable Omega Interferon plus Ribavirin for treatment of hepatitis C genotype-1

Intarcia Therapeutics has announced final results from a Phase 2 study of omega interferon with or without ribavirin in treatment-naive patients with genotype 1 chronic hepatitis C.

15 Apr 2007

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

GlaxoSmithKline has announced the initiation of a global, open-label, single group trial that will assess the efficacy, safety and tolerability of PROMACTA (eltrombopag olamine) in patients previously treated for chronic idiopathic thrombocytopenic purpura (ITP).

15 Apr 2007

Gleevec decreases cancer recurrence for GIST

Preliminary results from a large, randomized, placebo-controlled clinical trial for patients with primary gastrointestinal stromal tumor (GIST), a type of tumor usually found in the stomach or small intestine, showed that patients who received imatinib mesylate (Gleevec) after complete removal of their tumor were significantly less likely to have a recurrence of their cancer compared to those who did not receive imatinib.

15 Apr 2007

Genmab starts HuMax-EGFr combination study

Genmab A/S has announced it has initiated a Phase II study of HuMax-EGFr (zalutumumab) in combination with chemo-radiation to treat non small cell lung cancer (NSCLC).

15 Apr 2007

Cytokinetics initiates of phase II clinical trial for CK-1827452

Cytokinetics has announced the initiation of a Phase II clinical trials program evaluating CK-1827452, a novel cardiac myosin activator for the potential treatment of patients with either acutely decompensated or chronic heart failure.

15 Apr 2007

CuraGen announces results with Belinostat and Velafermin

CuraGen Corporation has announced that new preclinical data on belinostat (PXD101), a histone deacetylase (HDAC) inhibitor being investigated for the treatment of cancer, and velafermin, a protein being investigated for the prevention of severe oral mucositis, will be presented at the upcoming American Association for Cancer Research (AACR) 2007 Annual Meeting in Los Angeles, CA, April 14-18, 2007.

15 Apr 2007

First successful attempt to determine the structure of RfaH transcription factor

The results of a new study suggest that bacteria that cause diseases like bubonic plague and serious gastric illness can turn the genes that make them infectious on or off.

15 Apr 2007

Dysfunctional DNA repair pathways

Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things.

15 Apr 2007

Caloric content of dessert recipes associated with percent obese in the metropolitan cities

Research finds calorie-dense dessert recipes printed in major newspapers across the country may be contributing to obesity in large cities.

14 Apr 2007

Study describes impact of post-9/11 media exposure to dreams

Dream journals being kept by students in a college psychology class have provided researchers with a unique look at how people experienced the events of 9/11, including the influence that television coverage of the World Trade Center attacks had on people's levels of stress.

14 Apr 2007

Curcumin has anticancer effects

Curry powder is a mixture predominantly composed of turmeric root extract and other spices such as coriander and fenugreek.

14 Apr 2007

Drug Trial News

Lactate instead of glucose after traumatic brain injury

Study on accident related smoke inhalation shows most effected to be non-smokers

Men and women show different patterns of brain activity when viewing sexual stimuli

Gleevec available to patients in post-surgical GIST study

Monitoring chronic heart failure patients' health by phone helps

Gleevec shows great promise in preventing cancer recurrence

Transplant patients suffering from anemia have a greater mortality rate

People with two copies of a particular gene have a 70% higher risk of being obese

Nationwide survey of state Medicaid programs on "pay-for-performance" practices

Intarcia Therapeutics announces results from study of injectable Omega Interferon plus Ribavirin for treatment of hepatitis C genotype-1

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

Gleevec decreases cancer recurrence for GIST

Genmab starts HuMax-EGFr combination study

Cytokinetics initiates of phase II clinical trial for CK-1827452

CuraGen announces results with Belinostat and Velafermin

First successful attempt to determine the structure of RfaH transcription factor

Dysfunctional DNA repair pathways

Caloric content of dessert recipes associated with percent obese in the metropolitan cities

Study describes impact of post-9/11 media exposure to dreams

Curcumin has anticancer effects

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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