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Effectiveness of psychosocial treatments for bipolar disorder

This is a follow up study to one released last Thursday in the New England Journal of Medicine on the effects of antidepressants in the treatment of bipolar disorder. Both studies, called STEP-BD, were funded by the National Institute of Mental Health.

4 Apr 2007

People without health insurance more likely to forego routine physical exams

The lack of health insurance prompts people to forego routine physical exams and have a reduced awareness of cardiovascular risk factors and is associated with increased rates of stroke and death, researchers have concluded.

4 Apr 2007

New findings on hypoglycemic neuronal death

Treatment with insulin revolutionized the life of individuals with diabetes. However, because insulin acts to lower blood glucose levels, it can cause hypoglycemia (low levels of glucose in the blood), which, if prolonged, can lead to brain injury and coma.

4 Apr 2007

Insulin receptors play a critical role in promoting islet growth

A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.

4 Apr 2007

Inhaled corticosteroids deserve further consideration for lung cancer chemoprevention

Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer.

4 Apr 2007

TGF-beta found to be a major player in causing bronchopulmonary dysplasia

Researchers from Massachusetts General Hospital, in collaboration with scientists from the Genzyme Corporation, have identified a potential treatment for a chronic lung disease affecting premature infants.

4 Apr 2007

Genelabs Tech reaches agreement with FDA on special protocol assessment for phase III trial of Prestara in lupus

Genelabs Technologies has announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for a Phase III clinical trial of Prestara (prasterone) for treatment of systemic lupus erythematosus (lupus).

4 Apr 2007

Ropinirole reduces "off" time in Parkinson's

Parkinson disease patients taking the drug, ropinirole 24-hour prolonged release significantly reduced their daily "off" time in which Parkinson's symptoms like tremor, slowness, stiffness, and walking difficulty return as drugs wear off, according to a study published in the April 3, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

4 Apr 2007

Cost-effectiveness analysis of variceal ligation vs. beta-blockers for primary prevention of variceal bleeding

Endoscopic variceal ligation is cost-effective relative to beta-blockers for the prevention of variceal bleeding in cirrhotic patients if quality of life-years are considered.

4 Apr 2007

Call for improved screening for dating violence

Even though dating violence is common amongst teens, less than a quarter of U.S. child and adolescent psychiatrists report consistently screening for it, a new study finds.

4 Apr 2007

Boston Scientific announces enrollment in MAPS clinical trial

The MAPS trial (Matrix And Platinum Science) is designed to identify and investigate clinically relevant endpoints for evaluating the efficacy and durability of endovascular treatment of brain aneurysms.

4 Apr 2007

For overweight and obese individuals, the incidence of asthma increases by 50 percent

Asthma, a respiratory disease characterized by recurrent episodes of difficult breathing, wheezing, cough and thick mucus production, affected approximately 20.5 million Americans in 2004. Some common asthma triggers are allergic stimuli, infections, stress or strenuous exercise.

4 Apr 2007

NAFLD fibrosis score helps predict advanced fibrosis in patients with nonalcoholic fatty liver disease

Certain routine demographic, clinical, and laboratory values can be used to identify advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD).

4 Apr 2007

Walk your way to better health

What if someone told you, you could walk your way to better health?

4 Apr 2007

Are passive smoking, air pollution and obesity a greater mortality risk than major radiation incidents?

A new study has found that risks from radiation exposure to people involved in the Chernobyl incident may be much less significant than most of us think.

4 Apr 2007

Voluntary living liver donors should undergo a careful, but quick, workup

...and their desire for altruism should not be hampered by negativism from the transplant community, say the authors of a new study in the April issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS).

4 Apr 2007

Intensive therapy helps in battle against bipolar disorder

New results from the largest federally funded bipolar study ever conducted show that patients who receive psychotherapy in addition to medication get better faster from bipolar disorder's debilitating depression and stay better longer, according to a University of Colorado at Boulder researcher involved in the study.

4 Apr 2007

Surveillance for emergence of neuraminidase inhibitor resistant influenza viruses critically important

Use of certain common antiviral drugs during a recent influenza B epidemic in Japan showed the development of viruses with partial resistance to the drugs, according to a study in the April 4 issue of JAMA.

4 Apr 2007

Impact of secondhand smoke on periodontitis

A study published in this month's issue of the Journal of Periodontology found that subjects with periodontitis who were exposed to secondhand smoke were more likely to develop bone loss, the number one cause of tooth loss.

4 Apr 2007

Connection found between allergic diseases and autoimmune diseases

A new study by researchers at Children's Hospital and Regional Medical Center and the University of Washington (UW) identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases. The study was published in the April 1, 2007 edition of Nature Immunology.

4 Apr 2007