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New drug combo to cut cardiovascular disease

A major international study to test whether a new combination treatment that increases good "HDL" cholesterol prevents heart attacks and strokes will start to recruit patients later this year.

6 Jun 2006

Patients not receiving follow-up tests after positive screening for colon cancer

Study shows that more than 40 percent of patients who initially had received a positive result on a fecal occult blood test (FOBT) did not receive appropriate diagnostic follow-up tests such as a colonoscopy or barium enema in 2002.

6 Jun 2006

Knowledge helps prevent spread of herpes virus

A new study suggests that the risk of transmitting the virus that causes most cases of genital herpes could be cut in half by more testing and informing sexual partners of infection.

6 Jun 2006

Smoking cessation messages miss Asian Americans

Cigarettes are a particular problem among Asian-American immigrants, where smoking has been estimated to be more than 10 percent above the national average.

6 Jun 2006

Study shows skin rash in patients treated for liver cancer determines survival

In a study of a new chemotherapy drug for liver cancer, researchers found that the development of a skin rash correlated directly with the patient's response to treatment.

6 Jun 2006

Addition of gemcitabine to standard postoperative treatment increased pancreatic cancer patients' survival by 50 percent

Adding the cancer-fighting drug gemcitabine to standard therapy after surgery significantly improves survival for patients with the most common form of pancreatic cancer, according to a new multicenter study led by a University of Maryland radiation oncologist.

6 Jun 2006

Advanced prostate cancer can be treated successfully with intermittent chemotherapy

Advanced prostate cancer can be treated successfully with intermittent chemotherapy, according to a study conducted by Oregon Health & Science University Cancer Institute scientists.

6 Jun 2006

Hydrophobic statins not associated with increased breast cancer risk

A report published in the Journal of the National Cancer Institute found that women who took statins--the widely used cholesterol lowering drugs--do not face an increased breast cancer risk as had been suggested by some previous studies.

6 Jun 2006

Study confirms Gleevec's long-term benefits in treating advanced gastrointestinal stromal tumors

People with advanced gastrointestinal stromal tumors (GIST) who take Gleevec (imatinib) for prolonged periods continue to benefit from the drug, according to a five-year study by Oregon Health & Science University Cancer Institute researchers.

6 Jun 2006

Study finds ways to improve detection of blood clots in the lung

Largest study ever conducted to assess the role of contrast-enhanced multidetector computed tomographic (CT) angiography for diagnosing pulmonary embolism.

5 Jun 2006

Sunitinib therapy shows promise in children with metastatic gastrointenstinal stromal tumor

Children with a rare digestive-tract cancer that is resistant to front-line therapy have benefited from a newer targeted therapy that has been shown effective in adults, according to data from a small pilot study.

5 Jun 2006

Sunitinib malate shows promise against advanced form of lung cancer

Results of a multi-center clinical study of a drug currently approved for treatment of kidney cancer indicate that it may also be effective for people with recurrent and advanced lung cancer.

5 Jun 2006

Sunitinib malate drug shows significant benefits over standard treatment for advanced kidney cancer

According to a new study, the drug sunitinib malate (Sutent.) is more effective than the current standard cytokine treatment given as an initial therapy for patients with advanced kidney cancer, also known as metastatic renal cell carcinoma (mRCC).

5 Jun 2006

Trials funded by for-profit organizations more likely to report positive findings

Cardiovascular clinical trials published between 2000 and 2005 were significantly more likely to report positive findings if they were funded by for-profit organizations than those funded by not-for-profit organizations

5 Jun 2006

Taxotere combined with standard chemotherapy improves survival in advanced head and neck cancers

The addition of docetaxel (Taxotere) to an initial chemotherapy regimen for inoperable head and neck cancers reduced mortality by nearly 30 percent over three years following treatment compared to the standard two-drug combination.

5 Jun 2006

School-based obesity interventions may need to be tailored by gender

A study of 17,000 U.S. adolescents finds that black and Hispanic girls are less physically active than white girls, but that this difference is attributable to the schools they attend

5 Jun 2006

West Nile virus DNA vaccine shows promise in phase 1 trial

Vical Incorporated has announced that in a Phase 1 clinical trial, a West Nile virus (WNV) vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated

5 Jun 2006

HERA trial continues to demonstrate significant patient benefits from Herceptin

New 23-month follow-up data from HERA, one of the largest breast cancer trials ever carried out, show that Herceptin (trastuzumab) following standard chemotherapy significantly reduced the risk of death by 34% for women with early-stage HER2-positive breast cancer.

5 Jun 2006

New data show Enzastaurin's activity across multiple cancer cell lines

Eli Lilly and Company's enzastaurin, an investigational, multi-targeted therapy that is currently the focus of two global Phase III clinical trials, one for the treatment of glioblastoma and one in non-Hodgkin's lymphoma

5 Jun 2006

Female genital mutilation exposes women and babies to significant risk at childbirth

Women who have had Female Genital Mutilation (FGM) are significantly more likely to experience difficulties during childbirth and that their babies are more likely to die as a result of the practice.

4 Jun 2006

Drug Trial News

New drug combo to cut cardiovascular disease

Patients not receiving follow-up tests after positive screening for colon cancer

Knowledge helps prevent spread of herpes virus

Smoking cessation messages miss Asian Americans

Study shows skin rash in patients treated for liver cancer determines survival

Addition of gemcitabine to standard postoperative treatment increased pancreatic cancer patients' survival by 50 percent

Advanced prostate cancer can be treated successfully with intermittent chemotherapy

Hydrophobic statins not associated with increased breast cancer risk

Study confirms Gleevec's long-term benefits in treating advanced gastrointestinal stromal tumors

Study finds ways to improve detection of blood clots in the lung

Sunitinib therapy shows promise in children with metastatic gastrointenstinal stromal tumor

Sunitinib malate shows promise against advanced form of lung cancer

Sunitinib malate drug shows significant benefits over standard treatment for advanced kidney cancer

Trials funded by for-profit organizations more likely to report positive findings

Taxotere combined with standard chemotherapy improves survival in advanced head and neck cancers

School-based obesity interventions may need to be tailored by gender

West Nile virus DNA vaccine shows promise in phase 1 trial

HERA trial continues to demonstrate significant patient benefits from Herceptin

New data show Enzastaurin's activity across multiple cancer cell lines

Female genital mutilation exposes women and babies to significant risk at childbirth

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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