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Intensive statin therapy shows promise for inducing regression of coronary atherosclerosis

Patients treated with very intensive statin therapy lowered LDL-C levels on average by about 50 percent, increased HDL-C levels by 15 percent, and showed regression of coronary atherosclerosis

15 Mar 2006

Taking medications to lower blood pressure may be associated with a lower incidence of Alzheimer's disease

Taking medications to lower blood pressure, particularly those known as diuretics, may be associated with a lower incidence of Alzheimer's disease, according to a study in the May 2006 print issue of Archives of Neurology.

15 Mar 2006

Cognitive impairment appears to be common in Lou Gehrig disease

In a study of 40 patients with amyotrophic lateral sclerosis (ALS), about one-third showed evidence of cognitive impairment, but these deficits did not appear to be related to survival, according to a study in the March issue of Archives of Neurology.

15 Mar 2006

Telephone care and counseling for smoking cessation may help smokers quit

Smokers who receive telephone care and counseling for smoking cessation have higher rates of stopping smoking than those who receive routine care by health care providers, according to a study in the March 13 issue of Archives of Internal Medicine.

15 Mar 2006

Management of diabetic patients in a primary care setting can be improved by an intervention aimed at physicians

The intervention was individualized to each physician's record of action when patient glucose levels were high, and featured regular feedback on their performance.

15 Mar 2006

Association between levels of fine particulate matter pollution and mortality risk

Investigators who extended the Harvard Six Cities fine particulate air pollution study by eight years found that reduced levels of tiny particle pollution during this period lowered mortality risk for participants.

15 Mar 2006

Therapy for slightly raised blood pressure delays hypertension

A new study shows by giving a blood pressure drug to people with measurements above normal but not yet considered too high, the development of hypertension might be delayed.

15 Mar 2006

Statin drug reverses heart disease

Researchers say a high dose of a cholesterol-lowering statin drug can reverse the build-up of plaque in coronary arteries.

15 Mar 2006

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy.

15 Mar 2006

Discovery in yeast opens door to new source of information on DNA damage, repair, and cancer

The discovery in yeast cells of a genetic network that guards against lethal DNA damage is a first step in the creation of a database of disease-causing combinations of mutated human genes, according to researchers at The Johns Hopkins University School of Medicine led by Jef. D. Boeke, Ph.D.

15 Mar 2006

Memory, speed of thinking and other cognitive abilities get worse over time with marijuana use

Memory, speed of thinking and other cognitive abilities get worse over time with marijuana use, according to a new study published in the March 14, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

15 Mar 2006

Patients can have misguided view of asthma

Over half of adults with serious asthma believe they only have asthma when they have symptoms and these individuals are significantly less likely to take necessary medications during asymptomatic periods, according to a study in the March issue of Chest.

15 Mar 2006

Researchers evaluate efficacy, safety of anti-clotting drugs

Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI.

15 Mar 2006

One stent may be as good as two

Cardiologists increasingly use non-invasive methods to treat patients with diseased arteries that previously required open-heart surgery.

15 Mar 2006

Cells in mucus from lungs point to a unique screening method that could lead to earlier treatment of lung cancer

In a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer, say researchers in a study published in the March 15 issue of Cancer Research.

15 Mar 2006

Impact of a scientific presentation on community treatment patterns for primary breast cancer

The oral presentation of data from a single study at a national scientific conference can have an important impact on patient treatment, even before study publication or Food and Drug Administration (FDA) approval

15 Mar 2006

Human papillomavirus infections and incidence of squamous cell and basal cell carcinomas of the skin

Infection with human papillomavirus (HPV) types called beta HPVs may be associated with an increased risk of developing a major type of skin cancer known as squamous cell carcinoma (SCC)

15 Mar 2006

The safety and effectiveness of fondaparinux for heart attacks

The results of a large international cardiovascular trial will shed light on whether the addition of a new drug that prevents blood clotting, or thrombosis, can improve the treatment of the most serious form of heart attacks.

15 Mar 2006

Hospitalized schizophrenics more likely to have complications

A Johns Hopkins study of more than 1,700 patients with schizophrenia hospitalized for medical or surgical care unrelated to their mental disorder shows they are at least twice as likely as similar patients without schizophrenia to suffer dangerous and expensive adverse events.

15 Mar 2006

Capsaicin drives prostate cancer cells to kill themselves

Capsaicin, the stuff that turns up the heat in jalapeqos, not only causes the tongue to burn, it also drives prostate cancer cells to kill themselves, according to studies published in the March 15 issue of Cancer Research.

15 Mar 2006

Drug Trial News

Intensive statin therapy shows promise for inducing regression of coronary atherosclerosis

Taking medications to lower blood pressure may be associated with a lower incidence of Alzheimer's disease

Cognitive impairment appears to be common in Lou Gehrig disease

Telephone care and counseling for smoking cessation may help smokers quit

Management of diabetic patients in a primary care setting can be improved by an intervention aimed at physicians

Association between levels of fine particulate matter pollution and mortality risk

Therapy for slightly raised blood pressure delays hypertension

Statin drug reverses heart disease

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Discovery in yeast opens door to new source of information on DNA damage, repair, and cancer

Memory, speed of thinking and other cognitive abilities get worse over time with marijuana use

Patients can have misguided view of asthma

Researchers evaluate efficacy, safety of anti-clotting drugs

One stent may be as good as two

Cells in mucus from lungs point to a unique screening method that could lead to earlier treatment of lung cancer

Impact of a scientific presentation on community treatment patterns for primary breast cancer

Human papillomavirus infections and incidence of squamous cell and basal cell carcinomas of the skin

The safety and effectiveness of fondaparinux for heart attacks

Hospitalized schizophrenics more likely to have complications

Capsaicin drives prostate cancer cells to kill themselves

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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