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The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

A research study published in the March issue of Cancer Cell uses gene expression profiling to identify molecular profiles and signaling pathways associated with tumor aggressiveness and disease progression.

15 Mar 2006

Scientists gain better understanding of the behavior of leukemic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Inefficient cytotoxic T lymphocyte mediated killing of HIV-1 infected cells in vivo

HIV attacks the immune system by infecting and killing helper T lymphocytes (also called CD4 T cells), the white blood cells responsible for mobilizing the mediators of an immune response.

15 Mar 2006

Driving times and distances to hospitals with percutaneous coronary intervention in the United States

Diverting ambulances with patients suffering a heart to a hospital providing emergency angioplasty rather than a closer hospital with no ability to provide this specialized care, may be feasible for the majority of Americans

15 Mar 2006

Man-made chemical compound targets and kills tumor cells

A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed, researchers at the University of Illinois at Chicago report in a study highlighted in the March 15 issue of Cancer Research.

15 Mar 2006

Partial nephrectomy: urologists need to practice what we preach

There is no question in the urologic literature that partial nephrectomy (PN), particularly for renal masses ¡Ü 4cm, has demonstrated oncologic equipoise with radical nephrectomy (RN).

14 Mar 2006

Nature play before age 11 fosters adult environmental appreciation

If you want your children to grow up to actively care about the environment, give them plenty of time to play in the "wild" before they're 11 years old, suggests a new Cornell University study.

14 Mar 2006

Bariatric procedure offers long-term reduction in heart risk factors

As rates of obesity in America continue to soar, surgery has become an increasingly popular solution when diet and exercise regimens fail.

14 Mar 2006

Cardiac resynchronization therapy devices during hospital stays linked to better outcomes

Placement of devices that synchronize the pumping chambers of the heart in patients while they're hospitalized for a congestive heart failure episode appears to lower patients' risk of death or rehospitalization during at least the next two to three months, new research suggests.

14 Mar 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Cells have a natural defense against HIV

Scientists here have discovered a previously unknown mechanism that cells use to fight off the human immunodeficiency virus (HIV), the cause of AIDS.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Faxing alerts to physicians not enough to improve antidepressant adherence

"Our findings confirm that patient-specific alerts using faxes to physicians are not effective at improving patient adherence to antidepressant therapy in the absence of other complementary, coordinated interventions," said Bambauer.

14 Mar 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Does body image play a role in risky sexual behavior and attitudes?

In a recent Penn State study, sexually active male first-year college students who had a positive view of their appearance had a higher likelihood of having multiple sexual partners and engaging in unprotected sex.

14 Mar 2006

Diabetics overestimate healthy body weight

Heavier patients with diabetes are more likely to overestimate their "healthiest" body weight compared to those of normal weight, according to a study published in the current issue of Diabetes Care.

14 Mar 2006

Can fixing the heart fix the head?

A study presented during the American College of Cardiology's inaugural Innovation in Intervention: The i2 Summit 2006 in Atlanta, Ga., will answer intriguing questions about whether repairing a hole in the heart known as a patent foramen ovale (PFO) can ease the pain of severe migraine headaches.

14 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006