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X chromosome dosage compensation occurs in germ cells

X chromosome dosage compensation does occur in germ cells. A study published today in the open access journal Journal of Biology reveals that expression of the genes on the X chromosome is doubled in Drosophila germ cells to compensate for the missing second X chromosome.

17 Feb 2006

Hospitalization of a spouse can harm the wellbeing of his or her partner

In the largest study ever to quantify caregiver burden and the widower effect, researchers found that for people aged 65 and older, hospitalization of a spouse can harm the wellbeing of his or her partner and significantly contribute to that partner's death.

17 Feb 2006

Ovarian cancer responds to aspirin and chemotherapy drug cisplatin

A new study using ovarian cancer cell lines shows promise in treating the deadly disease by combining the chemotherapy drug cisplatin with an aspirin-like compound to make recurrent cancer cells less resistant to the chemotherapy.

17 Feb 2006

Unexpected rheumatoid arthritis discovery

What makes joints in people with rheumatoid arthritis, and related conditions like Lyme disease or lupus, so susceptible to attack by the body's immune system, leading to painful flare-ups and deterioration? The answer may surprise you.

17 Feb 2006

Children and teen-agers with bipolar disorder suffer from the illness differently than adults do

Their symptoms last longer and swing more swiftly from hyperactivity and recklessness to lethargy and depression.

17 Feb 2006

Tetrabenazine cuts down involuntary movements in Huntington's disease

The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement, according to a study in the February 14 issue of the journal Neurology.

17 Feb 2006

Botox finds a use in cancer treatment

The cosmetic treatment Botox may have a new use as an adjuvant to cancer therapy, providing an open door for chemotherapy and radiation treatments, according to a study published in the Feb. 15 issue of Clinical Cancer Research.

17 Feb 2006

Acupressure more effective than physical therapy in alleviating back pain

Acupressure (applying pressure with the thumbs or fingertips to the same points on the body stimulated in acupuncture) seems to be more effective in reducing low back pain than physical therapy, finds a study published online by the British Medical Journal.

17 Feb 2006

Inactivating Rad9 protien could make cancer cells easier to kill with ionizing radiation

The researchers found that Rad9, previously considered a "watchman" that checks for DNA damage, is actually a "repairman" that fixes dangerous breaks in the DNA double helix. They found Rad9 is especially active in telomeres, the protective ends of chromosomes.

17 Feb 2006

Farnesyltransferase inhibitor may improve progeria

UCLA researchers found that an experimental cancer drug improves the signs of progeria in a mouse model. Progeria is a rare genetic disease causing accelerated aging and cardiovascular disease in children. The new UCLA findings help to define a new strategy for treating children with progeria.

17 Feb 2006

Older asthmatics have increased cancer risk

New research shows that older adults with asthma are at an increased risk for developing cancer, and adults with asthma are twice as likely to suffer from heart disease and other chronic health conditions.

17 Feb 2006

Scientists map brain area that may help find human brain stem cells

A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells.

17 Feb 2006

Adjuvant hormonal therapy reduces contralateral breast cancer risk

The risk for a new cancer in the unaffected breast substantially increases in women diagnosed with unilateral, hereditary (non-BRCA) breast cancer, according to a new study.

17 Feb 2006

Study examines treatment to maintain blood pressure in those with disorder causing postural drops

Use of a medication called pyridostigmine alone or in combination with low-dose midodrine appears to improve standing blood pressure in patients with orthostatic hypotension, a fall in blood pressure associated with postural changes and standing

17 Feb 2006

Genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated

17 Feb 2006

Study takes in-depth look at fathering in families

A study published in the current issue of Family Process provides an in-depth look at fathering in families with young children and finds that the most involved fathers live outside traditional gendered roles.

17 Feb 2006

More physical activity does not lower risk of colon cancer

A prospective cohort study of 31,783 American women has found no significant association between levels of physical activity and colon cancer incidence.

17 Feb 2006

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages may be a source of inflammatory signals capable of impacting the effectiveness of androgen antagonists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) School of Medicine.

16 Feb 2006

Cutting angioplasty risks

Significant gains made through multi-hospital cooperative effort led by U-M Cardiovascular Center and funded by Blue Cross Blue Shield of Michigan.

16 Feb 2006

FOLFOX now treatment standard for colorectal cancer in the United States

One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review.

16 Feb 2006