Drug Trial News

RSS

Alfuzosin may improve double-J stent related symptoms

The first indwelling endoluminal ureteral stent was described over 30 years ago and has since become a routine and indispensable urologic tool. However, the side effects and patient morbidity associated with ureteral stents are not insignificant.

9 Mar 2006

Diabetics shown to have increased heart muscle mass

Diabetes strongly increases the risk of heart failure in all ethnic groups, but early effects of diabetes on the heart may differ depending on whether the subjects are white, African-American, Hispanic or Chinese.

9 Mar 2006

Whites have higher blood serum levels of perfluorochemicals than Hispanics and blacks

Whites have three times higher blood serum levels of perfluorochemicals (PFCs) than Hispanics and two times higher levels than blacks, according to a study scheduled for publication in the April 1 issue of the American Chemical Society's journal, Environmental Science & Technology.

9 Mar 2006

Nebivolol may restore damaged cardiovascular functions in African Americans

Tadeusz Malinski, Marvin & Ann Dilley White Professor of Chemistry and Biochemistry, found that the drug, currently under review by the U.S. Food and Drug Administration, acts on the level of oxidants lining the cardiovascular system and can restore levels of nitric oxide and reduce oxidative stress.

9 Mar 2006

Chronic fatigue syndrome linked to glandular fever

A seven-year tracking study has prompted scientists to suggest that chronic fatigue syndrome could be the result of brain injuries inflicted during the early stages of glandular fever.

9 Mar 2006

High narcotic use among headache sufferers

A new analysis of nearly 6.2 million insured patients shows that migraine was under diagnosed and often untreated.

9 Mar 2006

Reports of doctor shortages are wrong

Recent news reports that threaten a shortage of doctors to treat the burgeoning elderly population are wrong, according to researchers at Dartmouth Medical School's Center for the Evaluative Clinical Sciences (CECS).

9 Mar 2006

Rheumatoid arthritis does not increase risk of hearing loss

Mayo Clinic researchers have found that people with rheumatoid arthritis are no more likely to have hearing loss than other members of the general population.

9 Mar 2006

Effects of prenatal exposure to pesticides

Children in Ecuador whose mothers were exposed to pesticides while pregnant had increased blood pressure and diminished ability to copy geometric figures as compared to a control group, according to an epidemiological study in the March issue of Pediatrics.

9 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

New hepatitis drug much more effective

Chronic infection with the hepatitis B virus (HBV) is responsible for an enormous burden of disease throughout the world, including up to half of all cases of cirrhosis, end-stage liver disease, and hepatocellular carcinoma, a cancer of the liver.

9 Mar 2006

Many nursing home residents have poorly controlled pain due to inadequate medication treatment

"The inclusion of pain as a quality measure for both short-term and long-term residents is intended to provide an incentive for nursing homes to improve their practices in this area," say researchers.

9 Mar 2006

Repligen commences phase 2 trial of RG2417 for bipolar depression

Repligen Corporation today announced that the Company has initiated a Phase 2 clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression.

9 Mar 2006

Extraordinarily high rates of untreated mental illness reported by community studies are false

According to widely reported community-based research, almost half the U.S. population suffers from depression. But research by two sociologists indicates that percentage is greatly exaggerated or is a misrepresentation.

9 Mar 2006

Lilly launches phase III trial of Enzastaurin

One of the deadliest and rarest forms of cancer is the focus of a Phase III study initiated by Eli Lilly and Company today.

9 Mar 2006

Study supports guidelines for treatment of aortic regurgitation

Patients with leaky aortic heart valves appear to do better when the valves are replaced before significant symptoms develop, as recommended by the American College of Cardiology/American Heart Association guidelines, according to a new study in the Journal of the American College of Cardiology.

9 Mar 2006

Aspirin is beneficial in a wide range of men for protection against heart disease

Taking aspirin to prevent coronary heart disease is beneficial and cost-effective for a wider range of men than is often recognized, a study from the University of North Carolina at Chapel Hill has found.

9 Mar 2006

New way to study proteins in live cells

For the first time, Johns Hopkins researchers were able to easily jumpstart the activity of a well-known cancer protein in live cells with a small molecule, a strategy that pinpointed key players in the cancer process and can be used to determine new therapeutic targets.

9 Mar 2006

Antiretroviral therapy (ART) should be strongly considered in the management of infants infected with HIV

Antiretroviral therapy (ART) for infants born with HIV infection may be most effective when given in their first five months of life, according to a study published in the April 1 issue of The Journal of Infectious Diseases.

9 Mar 2006

Frontal cortex essential for understanding other people's actions

It has been known for over 100 years that if a person suffers a stroke in the left frontal cortex, he or she often suffers difficulties in speaking and with understanding language.

9 Mar 2006