Genomics

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Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Understanding how cancer cells evolve from healthy brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed.

29 Nov 2022

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Researchers investigate the genetic, immunological, and evolutionary factors that determine the vast variability observed in clinical manifestations of COVID-19.

28 Nov 2022

Rogue killer T cells associated with leukemia drive autoimmune diseases

Gene variants associated with leukemia can produce 'rogue' immune cells that drive autoimmune diseases, according to a new study from the Garvan Institute of Medical Research.

28 Nov 2022

MicroRNAs play a key role in the development of complex brains

Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems.

25 Nov 2022

Study investigates microbial composition in bat lung tissue

Announcing a new article publication for Zoonoses journal. Bats are the hosts of multiple pathogens, but the microbial composition of their lung tissues remains unknown.

25 Nov 2022

Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine.

25 Nov 2022

BW.1- a new Omicron subvariant that escapes immunity

Researchers reports the presence of mutations that aid in immune escape in the BW.1 Omicron subvariant.

25 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

Researchers from the Quadram Institute and the University of East Anglia have uncovered how resistance has helped drive the emergence of dominant strains of Salmonella.

24 Nov 2022

AI helps design synthetic DNA that controls cells' protein production

With the help of an AI, researchers at Chalmers University of Technology, Sweden, have succeeded in designing synthetic DNA that controls the cells' protein production.

24 Nov 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Animal study pinpoints a gene that is vital for development of earliest social behaviors

Little is known about how social behavior develops in the earliest stages of life. But most animals––including humans––are born with an innate ability to interact socially or form bonds with others. And that contributes to success throughout life.

24 Nov 2022

Krill oil rewires global gene expression programs and promotes healthy aging

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 21, entitled, "Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging."

24 Nov 2022

MYC proteins form hollow spheres that shield the genome of cancer cells

MYC genes and their proteins play a central role in the emergence and development of almost all cancers. They drive the uncontrolled growth and altered metabolism of tumour cells. And they help tumours hide from the immune system.

23 Nov 2022

Genome sequencing reveals a common ancestor for about 600 seemingly disparate fungi

About 600 seemingly disparate fungi that never quite found a fit along the fungal family tree have been shown to have a common ancestor, according to a University of Alberta-led research team that used genome sequencing to give these peculiar creatures their own classification home.

23 Nov 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

Unique resource for identifying new biomarkers of environmental exposures in early life

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects.

22 Nov 2022

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The

22 Nov 2022

UVA Health researchers develop new tool to advance genomics and disease research

UVA Health researchers have developed an important new tool to help scientists sort signal from noise as they probe the genetic causes of cancer and other diseases.

22 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022

Genomics

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Rogue killer T cells associated with leukemia drive autoimmune diseases

MicroRNAs play a key role in the development of complex brains

Study investigates microbial composition in bat lung tissue

Researchers discover a new function of CRISPR/Cas9 gene scissors

BW.1- a new Omicron subvariant that escapes immunity

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

AI helps design synthetic DNA that controls cells' protein production

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

Animal study pinpoints a gene that is vital for development of earliest social behaviors

Krill oil rewires global gene expression programs and promotes healthy aging

MYC proteins form hollow spheres that shield the genome of cancer cells

Genome sequencing reveals a common ancestor for about 600 seemingly disparate fungi

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Unique resource for identifying new biomarkers of environmental exposures in early life

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

UVA Health researchers develop new tool to advance genomics and disease research

Previously unknown links between genetic factors in ASD identified

Miracles Start in the Lab: the quest to find a vaccine to cure AIDS

Pioneering new medical imaging solutions

Pioneering new medical imaging solutions

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