Genomics

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Study: Variation in COVID-19 viral genome improves its ability to infect human cells

Researchers have shown that a variation in the viral genome of Covid-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today.

3 Jul 2020

Scientists test evolutionary fitness of older-mother offspring in various environments

The offspring of older mothers don't fare as well as those of younger mothers, in humans and many other species. They aren't as healthy, or they don't live as long, or they have fewer offspring themselves.

2 Jul 2020

NIH announces $75 million in funding to improve genomic risk assessments for diverse populations

The National Institutes of Health has announced the provision of $75 million in funding over five years for the Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network, which establish protocols and methodologies for improved genomic risk assessments for diverse populations and to integrate their use in clinical care.

1 Jul 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Genomic sequencing to provide precision medicine for aromatase deficiency

An international team of scientists from Switzerland Spain, has studied the genetic basis of aromatase deficiency, a rare metabolic disorder that prevents the production of estrogens in humans, according to new research in JCEM.

30 Jun 2020

GHGA to address need for access to genomic and phenomic data

In Germany, there is currently a lack of infrastructure to deal with high-volume biological and biomedical data, such as data found in medical records.

30 Jun 2020

Antibiotic resistance genes tend to persist in E. coli through 'genetic capitalism'

We have known for some time that over-use of antibiotics is causing a frightening increase in antibiotic resistance in bacteria, through the rapid spread of antibiotic resistance genes.

29 Jun 2020

Researchers identify a novel mutation through whole-exome sequencing

Long QT syndrome (LQTS), caused by an ion channel-related gene mutation, is a malignant heart disease with a clinical course of a high incidence of ventricular fibrillation and sudden cardiac death in the young.

27 Jun 2020

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.

26 Jun 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level.

25 Jun 2020

Certain genes that predispose to cancer also affect the immune system, study shows

The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth.

25 Jun 2020

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

24 Jun 2020

Researchers develop eDNA method to prevent emergence of pathogens

As the SARS-CoV-2 puts a new focus on zoonotic pathogens, a Washington State University researcher has developed a method to use environmental DNA (eDNA) to detect disease in the vast international trade of aquatic animals.

24 Jun 2020

New technique helps measure dNTP concentrations with greater sensitivity

A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer.

24 Jun 2020

Researchers develop less invasive genetic tools to understand cellular activity

Graduate student Ubadah Sabbagh placed a cold glass slide on the microscope. It was getting late and the lab was quiet.

24 Jun 2020

Long-term endurance training alters the activity of genes involved in metabolic health

Decades-long endurance training alters the activity of genes in human skeletal muscle that are important for metabolic health.

23 Jun 2020

Researchers identify genes that determine the optimal time of flowering

How do plants know when it is time to flower? Researchers at Martin Luther University Halle-Wittenberg (MLU) have studied this question and identified two genes that are key to this process.

23 Jun 2020

Patient genetics associated with wound microbiome composition and healing

In a first-of-its-kind study, researchers have determined that genetics may play a role in how wounds heal.

22 Jun 2020

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict the remaining lifespan in both sexes and the remaining years of fertility in women, according to the University of Utah Health scientists.

19 Jun 2020

Genomics

Study: Variation in COVID-19 viral genome improves its ability to infect human cells

Scientists test evolutionary fitness of older-mother offspring in various environments

NIH announces $75 million in funding to improve genomic risk assessments for diverse populations

A data-rich atlas of the developing human brain

Genomic sequencing to provide precision medicine for aromatase deficiency

GHGA to address need for access to genomic and phenomic data

Antibiotic resistance genes tend to persist in E. coli through 'genetic capitalism'

Researchers identify a novel mutation through whole-exome sequencing

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

Certain genes that predispose to cancer also affect the immune system, study shows

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

Researchers develop eDNA method to prevent emergence of pathogens

New technique helps measure dNTP concentrations with greater sensitivity

Researchers develop less invasive genetic tools to understand cellular activity

Long-term endurance training alters the activity of genes involved in metabolic health

Researchers identify genes that determine the optimal time of flowering

Patient genetics associated with wound microbiome composition and healing

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Irresistin: a ‘Poison Arrow’ to Defeat Antibiotic Resistance

The Role of Nutrition in Recovery from COVID-19

Improving cancer therapies by exploiting drug resistance in cancer

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