Genomics

RSS

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Gene variants linked to higher risk for nodular melanoma identified

Researchers from The University of Queensland and The Alfred hospital in Melbourne have identified gene variants which may contribute to people being at higher risk for nodular melanoma.

3 Oct 2023

NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

Genetic testing of one thousand embryos provides insights into human development and IVF

By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

3 Oct 2023

A better method to predict polygenic inheritance across multiple ancestries

Researchers report the results obtained from the use of a new PRS calculator called CT-SLEB on a multi-national GWAS database.

2 Oct 2023

Broken String Biosciences strengthens senior leadership team to accelerate product development and commercialization

Broken String Biosciences, a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced the expansion of its senior leadership team.

From Broken String Biosciences 2 Oct 2023

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders.

29 Sep 2023

Study shows how tumors "hijack" genetic program used by developing nerves

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

29 Sep 2023

New toolbox solves 50-year-old blood group mystery

Currently, a lot is known about which genes are responsible for our individual blood groups, however not much is understood about how and why the levels of the blood group molecules differ between one person and another.

29 Sep 2023

New framework for ethical microbiome research practices that include Indigenous communities

Every person hosts trillions of microorganisms, like bacteria and viruses, on their skin and in organs including those that make up the digestive tract, like their mouth, that collectively make up their microbiome.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

UKHSA donates advanced genomic surveillance equipment to CARPHA

This is a significant stride towards strengthening global genomic surveillance to track new variants and pathogens of pandemic and epidemic potential.

27 Sep 2023

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Rice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique in rodents, and their findings suggest that the efficiency of gene delivery improves within each targeted site when more sites are opened.

27 Sep 2023

Unions between close relatives may increase the risk of common diseases, study finds

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

26 Sep 2023

New method for multiancestry polygenic prediction holds promise for reducing health care disparities

A team led by researchers at Johns Hopkins Bloomberg School of Public Health and the National Cancer Institute has developed a new algorithm for genetic risk-scoring for major diseases across diverse ancestry populations that holds promise for reducing health care disparities.

25 Sep 2023

Researchers crack the genetic code of rare form of kidney cancer

The genetic code of a rare form of kidney cancer, called reninoma, has been studied for the first time. In the new paper, published today (25th September) in Nature Communications, researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital and The Royal Free Hospital also revealed a new drug target that could serve as an alternative treatment if surgery is not recommended.

25 Sep 2023

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023

Rare genetic variants involved in male-pattern hair loss identified

A receding hairline, a total loss of hair from the crown, and ultimately, the classical horseshoe-shaped pattern of baldness: Previous research into male pattern hair loss, also termed androgenetic alopecia, has implicated multiple common genetic variants.

22 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

Genomics

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Gene variants linked to higher risk for nodular melanoma identified

NIH grant to fund development of new gene therapy platform for brain diseases

Genetic testing of one thousand embryos provides insights into human development and IVF

A better method to predict polygenic inheritance across multiple ancestries

Broken String Biosciences strengthens senior leadership team to accelerate product development and commercialization

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

Study shows how tumors "hijack" genetic program used by developing nerves

New toolbox solves 50-year-old blood group mystery

New framework for ethical microbiome research practices that include Indigenous communities

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

UKHSA donates advanced genomic surveillance equipment to CARPHA

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Unions between close relatives may increase the risk of common diseases, study finds

New method for multiancestry polygenic prediction holds promise for reducing health care disparities

Researchers crack the genetic code of rare form of kidney cancer

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Rare genetic variants involved in male-pattern hair loss identified

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

Breaking Barriers: ANDYSMANCLUB's Fight for Men's Mental Health on World Mental Health Day

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Latest Life Science News