Genomics

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RNA steps up to protect the genome from DNA knots

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot.

13 Jun 2025

Redefining health science in the age of exposomics

We live in the age of -omics. We have genomics to study complete sets of DNA. We have proteomics focused on all the proteins within our cells.

13 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025

Lab-grown mini intestines reveal how Shigella infects human gut

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut.

12 Jun 2025

New CRISPR tool enables precise chemical modification of RNA in living cells

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects.

12 Jun 2025

Autophagy boosts precision in gene editing

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations.

12 Jun 2025

Bitter 'supertaster gene' tied to bipolar disorder and poor kidney function

People who carry a bitter 'supertaster gene' have been linked to various health conditions including bipolar disorder and poor kidney function, University of Queensland researchers have found.

12 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025

Study of monozygotic twins reveals genetic factors linked with differences in environmental sensitivity

An international team of researchers led by King's College London have identified genetic factors that may make some individuals more or less sensitive to the environments they experience.

10 Jun 2025

New computational tool identifies the gene combinations underlying complex illnesses

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma.

9 Jun 2025

Energy drain from antibiotics spurs bacteria to resist treatment faster

Antibiotics are supposed to wipe out bacteria, yet the drugs can sometimes hand microbes an unexpected advantage.

9 Jun 2025

Mitochondrial DNA variant predicts resistance to melanoma immunotherapy

Results from a new study help resolve the decade-long mystery of why many patients with the deadliest form of skin cancer do not respond to the latest cancer treatments.

6 Jun 2025

Genetic study reveals why some children respond better to myopia lenses

Myopia, or nearsightedness, has reached epidemic levels worldwide, particularly in East and Southeast Asia.

5 Jun 2025

Loss of Y chromosome in male immune cells linked to poorer cancer outcomes

A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune system function, which may explain why loss of Y is associated with lower cancer survival rates.

5 Jun 2025

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

5 Jun 2025

Understanding how base editing tools work at the molecular level

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

4 Jun 2025

Researchers map DNA regions that activate liver regeneration

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection.

4 Jun 2025

Early brain wiring holds clues to infant emotional development

In a comprehensive Genomic Press research article, scientists have uncovered remarkable insights into how the earliest brain connections shape infant emotional development, potentially offering new ways to identify children at risk for future behavioral and emotional challenges.

3 Jun 2025

Fruit fly model sheds light on genetic roots of cocaine addiction

In a new JNeurosci paper, Adrian Rothenfluh and colleagues from the University of Utah developed a fruit fly model of cocaine self-administration that can be used to explore the genetic underpinnings of cocaine addiction.

3 Jun 2025