Genomics

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Fungal antiviral responses controlled by RNA editing and transcription factor dynamics

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways.

23 May 2025

Powerful new toolkit targets vision loss in advanced retinal degeneration

Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes needed for their function and survival.

23 May 2025

Ancient DNA sheds light on evolution of relapsing fever bacteria

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained and lost genes in the process.

22 May 2025

Study uncovers first proof of introners jumping between species

DNA is the genetic code that provides the biological instructions for every living species, but not every bit of DNA helps the species survive. Some pieces of DNA are more like parasites, along for the ride and their own survival.

22 May 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

New study links fetal mutations to early pregnancy loss

In a study published in Nature today "Sequence diversity lost in early pregnancy," scientists from deCODE genetics, a subsidiary of Amgen, estimate that around one in 136 pregnancies are lost due to new mutations in the fetus.

21 May 2025

New CRISPR technology delivers RNA precisely to repair damaged brain cells

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury.

21 May 2025

New genetic mutation linked to increased prostate cancer risk in Ashkenazi Jewish men

Identifying and classifying gene mutations - which are the permanent changes in a person's DNA genetic code - are critical in better understanding, and with research, eventually treating or preventing, the diseases with which they are linked.

21 May 2025

Researchers discover a genetic link to long COVID

An international team of researchers has found a genetic link to long-term symptoms after COVID-19.

21 May 2025

New multiple myeloma-like score assesses disease severity and risk of progression to active cancer

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

21 May 2025

Discovery unravels two populations of gonadotrophs in the pituitary gland

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought.

21 May 2025

Study uncovers common trigger across gene mutations that cause ALS

Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS.

19 May 2025

Newly discovered Cat1 protein halts viral infections by depleting cellular fuel

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders.

18 May 2025

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black and non-Hispanic white veterans, but similar survival outcomes when both groups had equal access to care.

16 May 2025

Study reveals subtle effects of recessive mutations on health and reproduction

As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring.

16 May 2025

New gene editor evoCAST enables precise insertion of complete genes

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

15 May 2025

Genomics

Fungal antiviral responses controlled by RNA editing and transcription factor dynamics

Powerful new toolkit targets vision loss in advanced retinal degeneration

Ancient DNA sheds light on evolution of relapsing fever bacteria

Study uncovers first proof of introners jumping between species

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

New study links fetal mutations to early pregnancy loss

New CRISPR technology delivers RNA precisely to repair damaged brain cells

New genetic mutation linked to increased prostate cancer risk in Ashkenazi Jewish men

Researchers discover a genetic link to long COVID

New multiple myeloma-like score assesses disease severity and risk of progression to active cancer

Discovery unravels two populations of gonadotrophs in the pituitary gland

Study uncovers common trigger across gene mutations that cause ALS

Newly discovered Cat1 protein halts viral infections by depleting cellular fuel

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

Study reveals subtle effects of recessive mutations on health and reproduction

New gene editor evoCAST enables precise insertion of complete genes

New genetic database sheds light on Brazil’s ancestry and disease risks

Customized CRISPR gene editing therapy successfully treats infant with rare disease

Two genetic variants linked to breast cancer discovered in black South African women

University of Tokyo team accelerates bacterial genome evolution in the lab

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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