Genomics

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Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Machine learning tool can enhance the inference of complex cell identities

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs.

13 Jan 2023

New breakthrough in understanding the genetic causes of "malformations of cortical development"

Epilepsy is present in 4% of the population, and is among the most common brain disorders in children. Modern medicine can prevent most seizure recurrences, but approximately 20% of patients do not respond to treatment.

12 Jan 2023

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

A new CRISPR-Cas9 approach that targets a detrimental signaling pathway in the heart confers protection from ischemia/reperfusion injury, according to a study in mice.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park.

From BioGrad 12 Jan 2023

Three genes found to be directly associated with cleft lip and palate

Researchers are finding more genes directly associated with cleft lip and palate.

11 Jan 2023

Circadian clock can preserve fitness even under long-term nutritional stress

Cells with a functioning molecular clock are better able to adapt to changes in glucose supply and can recover faster from long-term starvation, according to a study published today in eLife.

10 Jan 2023

Developing new tools to accelerate spatial genomics and drug discovery

We speak to Dr. George Emanuel from Vizgen about their new MERSCOPE Platform and how it is accelerating the field of drug discovery by combining both single-cell and spatial genomics.

From Vizgen 10 Jan 2023

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

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From MGI 10 Jan 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Investigators at Cedars-Sinai have created a unique and detailed molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

9 Jan 2023

Comparison of genetic codes reveals how humans and other mammals lost their hair

Orangutans, mice, and horses are covered with it, but humans aren't. Why we have significantly less body hair than most other mammals has long remained a mystery.

5 Jan 2023

Irish study demonstrates a genetic effect on the response to obesity treatments

Collaborative research between University of Galway and Brunel University London has found that patients with severe and complicated obesity respond differently to a dietary weight loss program based on their genes.

5 Jan 2023

Genotype-first approach uncovers new relationships between genes and clinical conditions

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care.

5 Jan 2023

Evolutionary advantage of jumping genes in a fungus discovered

A fungus that infects salamanders contains multiple copies of the same "jumping genes", scientists have discovered.

4 Jan 2023

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

Structure and function of a newly discovered CRISPR immune system revealed

In a rare feat, Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published not one, but two seminal papers in a top-tier, peer-reviewed journal this week.

4 Jan 2023

Genomics

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Machine learning tools help unravel why human accelerated regions evolved so quickly

Machine learning tool can enhance the inference of complex cell identities

New breakthrough in understanding the genetic causes of "malformations of cortical development"

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

Three genes found to be directly associated with cleft lip and palate

Circadian clock can preserve fitness even under long-term nutritional stress

Developing new tools to accelerate spatial genomics and drug discovery

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Comparison of genetic codes reveals how humans and other mammals lost their hair

Irish study demonstrates a genetic effect on the response to obesity treatments

Genotype-first approach uncovers new relationships between genes and clinical conditions

Evolutionary advantage of jumping genes in a fungus discovered

Recently discovered protein holds potential for the development of new tests for infectious diseases

Structure and function of a newly discovered CRISPR immune system revealed

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Using the power of light to transform analytical workflows in the life sciences

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