Genomics

RSS

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

New ISS investigation expands genes in space toolkit for student spaceflight experiments

For nearly a decade, Genes in Space™ has challenged students to develop spaceflight experiments that use biotechnology to address spaceflight challenges.

4 Mar 2024

Prioritizing biologically motivated approaches in Mendelian randomization studies

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease.

1 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Newly identified Enterococcus species shed light on antibiotic resistance spread

Antibiotic-resistant infection is projected to catch up to cancer as the leading cause of death by 2050, making understanding and limiting the spread of antibiotic-resistant bacteria a priority worldwide.

29 Feb 2024

Scripps Research scientists uncover plausible pathway for protocell formation

Roughly 4 billion years ago, Earth was developing conditions suitable for life. Origin-of-life scientists often wonder if the type of chemistry found on the early Earth was similar to what life requires today.

29 Feb 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

NIH funds study on neural mechanisms behind autism and sound sensitivity

Supported by a $2 million R01 grant from the National Institutes of Health, the Auerbach Lab at the Beckman Institute for Advanced Science and Technology will examine how different genes associated with autism spectrum disorders may similarly impact our brain's neurons, resulting in heightened sensitivity to sounds.

28 Feb 2024

GTF2I gene's role in Williams syndrome and autism unraveled

Individuals with the neurodevelopmental disorder Williams syndrome have a gregarious "cocktail party" personality, while those with the opposite genetic alteration, in contrast, tend to have autistic traits and are prone to struggle socially.

28 Feb 2024

New tool can streamline the analysis of complex epigenome and epitranscriptome data

Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact in diseases.

28 Feb 2024

Research identifies genetic change associated with human tail loss

A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys, finds a new study led by researchers at NYU Grossman School of Medicine.

28 Feb 2024

Genetic risk tool could aid early diagnosis and treatment of multiple sclerosis patients

Young people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start effective treatments.

28 Feb 2024

Caffeine's protective effects against obesity and joint diseases supported by genetic study

The effects of caffeine levels in circulation by considering genetically predicted variations in caffeine metabolism.

28 Feb 2024

SickKids scientists lay the groundwork for early detection of cardiomyopathy

In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital for Sick Children (SickKids) have laid the groundwork for early detection of and future precision therapies for cardiomyopathy.

27 Feb 2024

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago, a new study reveals.

27 Feb 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

Wayne State researchers lead $9.6 million study on cancer genetics in African Americans

A team of researchers from Wayne State University and the Barbara Ann Karmanos Cancer Institute has received a five-year, $9.6 million grant from the National Cancer Institute of the National Institutes of Health for the study "Genetic Variation in Cancer Risk and Outcomes in African Americans."

26 Feb 2024

Ultima announces UG 100™ and reveals disruptive cost and accuracy profile to enable the era of the $100 genome and beyond

Today, the Company is also introducing ppmSeqTM, a disruptive new mode for extreme raw read accuracy in calling single nucleotide variants (SNVs). ppmSeqTM is a new proprietary feature enabled by Ultima’s unique approach that dramatically improves the raw read accuracy of calling SNVs by removing sample errors introduced upstream of the sequencing workflow.

From Ultima Genomics, Inc. 26 Feb 2024

Genomics

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

New ISS investigation expands genes in space toolkit for student spaceflight experiments

Prioritizing biologically motivated approaches in Mendelian randomization studies

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Exploring the epigenetic impact of smoking across racial and ethnic groups

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Newly identified Enterococcus species shed light on antibiotic resistance spread

Scripps Research scientists uncover plausible pathway for protocell formation

Breakthrough CRISPR technique unlocks insights about cancer immunology

NIH funds study on neural mechanisms behind autism and sound sensitivity

GTF2I gene's role in Williams syndrome and autism unraveled

New tool can streamline the analysis of complex epigenome and epitranscriptome data

Research identifies genetic change associated with human tail loss

Genetic risk tool could aid early diagnosis and treatment of multiple sclerosis patients

Caffeine's protective effects against obesity and joint diseases supported by genetic study

SickKids scientists lay the groundwork for early detection of cardiomyopathy

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

Mapping the brain: How cell types and location influence Parkinson’s disease

Wayne State researchers lead $9.6 million study on cancer genetics in African Americans

Ultima announces UG 100™ and reveals disruptive cost and accuracy profile to enable the era of the $100 genome and beyond

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest Life Science News