Genomics

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Study finds striking epigenetic differences in the airway cells of adult children born to asthmatic mothers

Asthma is a chronic condition that affects 25 million people in the United States. Having a mother with asthma is an important risk factor and a new study may explain why.

6 Jun 2022

Study offers recommendations for improving statistical inference in population genomics

The second century Alexandrian astronomer and mathematician Claudius Ptolemy had a grand ambition. Hoping to make sense of the motion of stars and the paths of planets, he published a magisterial treatise on the subject, known as the Almagest.

6 Jun 2022

Addressing the ‘trust factor’: South Carolina researchers tackle health disparities using genetics

Quenton Tompkins' family tree is deeply rooted in rural McCormick County, South Carolina.

6 Jun 2022

Combinations of multiple genetic factors play a role in the broad spectrum of autism

Autism Spectrum Disorder (ASD) is referred to as a "spectrum" because clinical features of ASD range from mild social impairments in some people to severe intellectual disability or epilepsy in others.

3 Jun 2022

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division.

3 Jun 2022

Lack of diversity in genomic research could deprive Africans of life-changing care for chronic diseases

The lack of diversity in genomic research could mean Africans are missing out on potential life-changing care for chronic health disorders, according to a new study published in Nature Medicine.

3 Jun 2022

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

Hospital-acquired infections (HAIs) are often particularly difficult to treat because the pathogens have developed resistance to common antibiotics.

3 Jun 2022

New study uncovers the impact of genetic mutations on lifelong blood cell production

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life.

1 Jun 2022

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.

31 May 2022

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

The loss of genome heterogeneity in CoVs leads to high viral fitness variants that adapt to the human host.

31 May 2022

Fast-breeding sea urchin species could open new avenues for genetic research

Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.

29 May 2022

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the journal Cell Reports.

27 May 2022

Researchers identify a gene that plays vital role in the innate human immune system

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on the attack against a foreign presence.

27 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Exposure of microbial communities to antibiotics could facilitate the spread of plasmid-encoded genes

DNA molecules called plasmids – some of which protect bacteria from antibiotics – can spread rapidly through bacterial "communities" that are treated with antibiotics, new research shows.

27 May 2022

New Spex NanoSNAP™ provides high performance measurements of nucleic acids and proteins in a snap

New Spex NanoSNAP™ provides high performance measurements of nucleic acids and proteins in a snap.

26 May 2022

UCLA researchers discover key molecular mechanism behind memory linking

Our brains rarely record single memories-;instead, they store memories into groups so that the recollection of one significant memory triggers the recall of others connected by time.

25 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Genomics

Study finds striking epigenetic differences in the airway cells of adult children born to asthmatic mothers

Study offers recommendations for improving statistical inference in population genomics

Addressing the ‘trust factor’: South Carolina researchers tackle health disparities using genetics

Combinations of multiple genetic factors play a role in the broad spectrum of autism

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Lack of diversity in genomic research could deprive Africans of life-changing care for chronic diseases

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

New study uncovers the impact of genetic mutations on lifelong blood cell production

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

Fast-breeding sea urchin species could open new avenues for genetic research

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

Researchers identify a gene that plays vital role in the innate human immune system

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Exposure of microbial communities to antibiotics could facilitate the spread of plasmid-encoded genes

New Spex NanoSNAP™ provides high performance measurements of nucleic acids and proteins in a snap

UCLA researchers discover key molecular mechanism behind memory linking

Researchers identify the genetic causes of three mitochondrial diseases using new approach

Study unveils the novel driver of cardiomyocyte loss

New model reveals cancer-driving mutations

BICO; Combining Life Sciences Solutions to Further Human Health

Discussing tools and resources to support the bladder cancer patient community

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