Genomics

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Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

HMGN1 gene linked to heart problems in people with Down syndrome

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life.

22 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Molecular evidence connects higher childhood cognitive function to longer lifespan

Researchers led by Dr. W. David Hill at the University of Edinburgh have identified a significant genetic correlation between childhood cognitive function and longevity, providing the first molecular genetic evidence that intelligence measured in youth shares genetic factors with lifespan.

21 Oct 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

New insights reveal persistent genome structure during cell division

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material.

17 Oct 2025

Researchers discover new genetic cause of hereditary optic atrophy

A research team from the Medical University of Vienna and the Medical University of Graz has discovered a previously unknown genetic cause of hereditary optic atrophy, a degenerative disease of the optic nerve associated with gradual loss of vision.

16 Oct 2025

New breakthrough enables whole genome sequencing in hours

Boston Children's Hospital, along with Broad Clinical Labs and Roche Sequencing Solutions, has demonstrated that rapid genomic sequencing and interpretation are achievable in a matter of hours.

16 Oct 2025

CRISPR therapy shows promise against influenza in human lung chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

15 Oct 2025

Child maltreatment leaves measurable biological scars on children's DNA

Child maltreatment, which includes abuse and neglect, is one of the most serious public health concerns worldwide.

15 Oct 2025

Pioneering personalized medicine by deciphering depression's complex biological web

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that fundamentally reshape international understanding of depression genetics.

15 Oct 2025

SPT Labtech and 10X Genomics partner to automate single cell workflows

SPT Labtech, a pioneer in the design and development of laboratory automation and liquid handling solutions, and 10x Genomics, Inc., a leader in single cell and spatial biology, today announced a strategic partnership to provide automated workflows for single cell research.

15 Oct 2025

New insights can reshape psychiatric practice across continents

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Bruce M. Cohen discusses results and insights that are reshaping international approaches to understanding and treating neuropsychiatric disorders.

14 Oct 2025

Genetic study reveals links between cannabis use and mental health

University of California San Diego of Medicine researchers, in collaboration with the genetic testing company 23andMe, have identified regions of the human genome associated with cannabis use, uncovering new relationships with psychiatric, cognitive and physical health.

13 Oct 2025

How genomic screening in newborns found 16 hidden disorders standard tests overlooked

Genomic newborn screening using whole-genome sequencing identified 1.6% of infants with high-chance, treatable genetic conditions, far beyond the capacity of standard biochemical screening. The BabyScreen+ study demonstrated clinical impact, cascade diagnoses, and strong parental acceptance, while highlighting challenges in scalability and equity.

13 Oct 2025

SPT Labtech and Agilent introduce automated target enrichment protocols for genomic workflows

SPT Labtech, a pioneer in the design and development of laboratory automation and liquid handling solutions, and Agilent Technologies Inc. ("Agilent"), a global leader in analytical and clinical laboratory technologies, today announced the introduction of automated target enrichment protocols on SPT Labtech's firefly®+ platform.

13 Oct 2025

Microbial genetic variation shapes neurocognitive behavior in sheep

The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota, plasma metabolites, and neurocognitive behavioral phenotype data.

10 Oct 2025

Genetic study reveals unique mutations in Chinese patients with hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM), a common genetic heart disorder, is often caused by mutations in sarcomere-related genes.

10 Oct 2025

Errors in EPG5 gene implicated in rare infant condition and adult neurodegenerative diseases

Errors in a gene known to cause a serious neurodevelopmental condition in infants are also linked to the development of Parkinson's disease in adolescence and adulthood, according to new research.

9 Oct 2025

Takara Bio USA, Inc. announces a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology

Takara Bio USA, Inc. ("Takara Bio USA"), a wholly owned subsidiary of Takara Bio Inc. ("Takara Bio"), today announced a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology.

9 Oct 2025

Genomics

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

HMGN1 gene linked to heart problems in people with Down syndrome

Genetic inflammatory signature defines depression subtypes and treatment response

Molecular evidence connects higher childhood cognitive function to longer lifespan

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

New insights reveal persistent genome structure during cell division

Researchers discover new genetic cause of hereditary optic atrophy

New breakthrough enables whole genome sequencing in hours

CRISPR therapy shows promise against influenza in human lung chips

Child maltreatment leaves measurable biological scars on children's DNA

Pioneering personalized medicine by deciphering depression's complex biological web

SPT Labtech and 10X Genomics partner to automate single cell workflows

New insights can reshape psychiatric practice across continents

Genetic study reveals links between cannabis use and mental health

How genomic screening in newborns found 16 hidden disorders standard tests overlooked

SPT Labtech and Agilent introduce automated target enrichment protocols for genomic workflows

Microbial genetic variation shapes neurocognitive behavior in sheep

Genetic study reveals unique mutations in Chinese patients with hypertrophic cardiomyopathy

Errors in EPG5 gene implicated in rare infant condition and adult neurodegenerative diseases

Takara Bio USA, Inc. announces a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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