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Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Gout flares associated with subsequent cardiovascular events

Experts at the University of Nottingham, in collaboration with experts at Keele University, have found that the risk of heart attacks and strokes temporarily increases in the four months after a gout flare.

2 Aug 2022

New treatment gives hope for people challenged with chronic back pain

People challenged with chronic back pain have been given hope with a new treatment that focuses on retraining how the back and the brain communicate, a randomized controlled trial run by researchers at UNSW Sydney and Neuroscience Research Australia and several other Australian and European universities has shown.

2 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

New, non-invasive imaging method may help detect an early indicator of glaucoma

A new, non-invasive ocular imaging method may be able to detect an early indicator of glaucoma in time to prevent disease progression and vision loss, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

2 Aug 2022

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Disease of the microscopic blood vessels that feed the white matter of our brain is associated with worse cognitive function and memory deficits in individuals with Alzheimer's, scientists report.

2 Aug 2022

Acupuncture therapy may be a useful tool to ward off type 2 diabetes

It's been used for thousands of years to treat a variety of illnesses - and now acupuncture could also help fight one of the 21st century's biggest health challenges.

2 Aug 2022

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

Socioeconomic deprivation, including neighborhood disadvantages and persistent low wages, are associated with higher dementia risk, lower cognitive performance and faster memory decline, according to several studies reported today at the Alzheimer’s Association International Conference 2022 in San Diego and virtually.

2 Aug 2022

17 recommendations for better communication with study participants affected by early stopping of clinical trials

Participants in clinical trials can feel abandoned and adrift when their studies end early and they are the last to be informed, or they hear about it first from news or social media.

2 Aug 2022

Study sheds light on the role of blood pressure self-monitoring in diabetes management

JMIR Publications recently published "Blood Pressure Monitoring as a Digital Health Tool for Improving Diabetes Clinical Outcomes: Retrospective Real-world Study" in the Journal of Medical Internet Research (JMIR), which reported that there is a lack of understanding of the association between blood glucose (BG) and blood pressure (BP) levels when using digital health tools.

2 Aug 2022

VR balance training is highly effective in improving balance ability of patients with Parkinson's disease

JMIR Publications recently published "Benefits of Virtual Reality Balance Training for Patients With Parkinson Disease: Systematic Review, Meta-analysis, and Meta-Regression of a Randomized Controlled Trial" in JMIR Serious Games, which reported that virtual reality (VR) balance training is increasingly being pursued in biomedical research, specifically with respect to investigating balance ability with VR.

2 Aug 2022

Researchers characterize a novel gene likely to cause neurological disorders in humans

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/MedUni Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder. Using data from two young patients with neurological symptoms, the researchers from both groups found evidence of a novel function for the FIBCD1 gene in the brain, and a potentially pivotal role in diseases such as autism, ADHD, schizophrenia, and neurodegenerative disorders including Alzheimer's. The study makes an important contribution to the understanding of the extracellular matrix in the brain and its associated neurological diseases.

2 Aug 2022

Mobile app-based program substantially improves cardiac rehabilitation participation

JMIR Publications recently published "The Impact of a Mobile App on Participation in Cardiac Rehabilitation and Understanding Barriers to Success: Comparative Cohort Study" in JMIR Cardio which evaluated the impact on cardiac rehabilitation (CR) participation rates associated with the addition of the option of mobile app–based CR for patients declining conventional CR.

2 Aug 2022

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The University of Texas MD Anderson Cancer Center and TransCode Therapeutics, Inc. today announced a strategic alliance to advance TransCode's pipeline of RNA-targeted oncology therapeutic and diagnostic candidates.

2 Aug 2022

Personal health records may be useful for patient self-management and communication in colorectal cancer networks

JMIR Publications recently published "Uses of Personal Health Records for Communication Among Colorectal Cancer Survivors, Caregivers, and Providers: Interview and Observational Study in a Human-Computer Interaction Laboratory" in JMIR Human Factors which reported that personal health records (PHRs) may be useful for patient self-management and participation in communication with their caregivers and health care providers.

2 Aug 2022

Study challenges the perspective that autistic adults cannot read facial emotion expressions

There's a common perception that autistic individuals are poor at recognizing others' emotions and have little insight into how effectively they do so.

2 Aug 2022

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

In a new study, researchers highlighted the urgent need to substitute highly processed carbohydrates with minimally processed carbohydrates or healthy fats to cease the obesity pandemic that continues relentlessly.

2 Aug 2022

Black patients with severe heart failure have a lower chance of getting LVAD care

Black people and women with severe heart failure who might be good candidates for surgery to implant a heart-assisting device have a lower chance of actually getting that operation than white patients, or male patients, a new study finds.

1 Aug 2022

Medical Condition News

Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Gout flares associated with subsequent cardiovascular events

New treatment gives hope for people challenged with chronic back pain

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

New, non-invasive imaging method may help detect an early indicator of glaucoma

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Acupuncture therapy may be a useful tool to ward off type 2 diabetes

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

17 recommendations for better communication with study participants affected by early stopping of clinical trials

Study sheds light on the role of blood pressure self-monitoring in diabetes management

VR balance training is highly effective in improving balance ability of patients with Parkinson's disease

Researchers characterize a novel gene likely to cause neurological disorders in humans

Mobile app-based program substantially improves cardiac rehabilitation participation

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

Personal health records may be useful for patient self-management and communication in colorectal cancer networks

Study challenges the perspective that autistic adults cannot read facial emotion expressions

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

Black patients with severe heart failure have a lower chance of getting LVAD care

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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