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Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

How do female sex hormones affect sleep, and memory?

Scientists describe the relationship between biological sex, memory, sleep, and hormones in relation to the risk of Alzheimer's disease and related dimentias.

7 Aug 2022

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

Researchers describe the impact of placental morphological changes in COVID-19 on pregnancy outcomes.

7 Aug 2022

French study on cardiovascular disease incidence during COVID pandemic and vaccination campaign

Researchers describe failures of the French healthcare system as reflected by increased hospitalizations due to certain acute cardiovascular diseases in 2021.

7 Aug 2022

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

5 Aug 2022

Five-year, $2.7 million grant could help determine the best treatment for lung cancer patients

The goal: Improve survival rates for lung cancer patients. The question researchers want to answer: Are there new ways to determine the best treatment for these patients?

5 Aug 2022

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

5 Aug 2022

Research suggests a new nanomedicine strategy for treatment of IBD patients

Inflammatory bowel disease (IBD), also known as "green cancer", is a chronic, non-specific disease of the intestine. IBD includes ulcerative colitis and Crohn's disease, both of which tend to be debilitating, lifelong conditions that can prove fatal in severe cases. Currently, there is no cure for IBD. The main clinical treatments are drugs such as aminosalicylic acid preparations and corticosteroids, but they are often accompanied by gastrointestinal problems, anemia, and various intestinal complications. Finding alternative, more effective options is a priority for researchers.

5 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Monoamine neurotransmitters such as serotonin and dopamine play important roles in our cognitive and emotional functions.

5 Aug 2022

Rural early-onset Alzheimer’s patients less likely to see specialists than city dwellers

Rural Americans suffering from early-onset Alzheimer's are less likely than city dwellers to be seen by specialists and receive tests that can benefit both them and their families, new research has found.

5 Aug 2022

Vascular dysfunction may be the cause of metabolic changes that can lead to diabetes, study suggests

A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond to insulin and cannot make use of the glucose (sugar) in the blood stream.

5 Aug 2022

Cognitive rehab may help older adults clear covid-related brain fog

Eight months after falling ill with covid-19, the 73-year-old woman couldn't remember what her husband had told her a few hours before. She would forget to remove laundry from the dryer at the end of the cycle. She would turn on the tap at a sink and walk away.

5 Aug 2022

Skin cancer is a risk no matter the skin tone. But it may be overlooked in people with dark skin.

Brykyta Shelton found herself standing in a checkout line of a big-box retailer, uncomfortably aware as a woman ahead of her stared at her sandaled feet.

5 Aug 2022

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Future treatments for advanced cancer could work by sticking cancer cells in place and preventing their spread around the body. A new study by researchers at the University of California, Davis, and the University of Washington shows how an antibody strengthens bonds between cells. The work is published Aug. 3 in Proceedings of the National Academy of Sciences.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Eating fish and seafood reduces risk of rheumatoid arthritis

Scientists determine the relationship between meat consumption and rheumatoid arthritis.

4 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells) - cells in the pancreas that produce and distribute insulin.

4 Aug 2022

Medical Condition News

Optically controlled local heat-pulse method manipulates temperature in cells

How do female sex hormones affect sleep, and memory?

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

French study on cardiovascular disease incidence during COVID pandemic and vaccination campaign

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

Five-year, $2.7 million grant could help determine the best treatment for lung cancer patients

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

Research suggests a new nanomedicine strategy for treatment of IBD patients

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Rural early-onset Alzheimer’s patients less likely to see specialists than city dwellers

Vascular dysfunction may be the cause of metabolic changes that can lead to diabetes, study suggests

Cognitive rehab may help older adults clear covid-related brain fog

Skin cancer is a risk no matter the skin tone. But it may be overlooked in people with dark skin.

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Heart failure arises from mutations in distinct genes, study finds

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Study provides new insight into the cellular and molecular biology of human heart failure

Eating fish and seafood reduces risk of rheumatoid arthritis

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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