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Immune cells beyond CAR-T cells affect the durability of response to BCMA CAR T therapy in myeloma

Patients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer markers of immune cell exhaustion, and distinct changes to immune cell populations were more likely to have longer progression-free survival (PFS) after treatment with BCMA-targeted T-cell therapy.

30 Aug 2022

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

The brain activity patterns during sleep shed light on the neurobiology behind a genetic condition called 22q11.2 Deletion Syndrome (22q11.2DS) and could be used as a biomarker to detect the onset of neuropsychiatric disorders in people with 22q11.2DS.

30 Aug 2022

Abdominal obesity increases risk of pancreatic cancer

Researchers report that abdominal obesity determined by body mass index adjusted waist-to-hip ratio is a significant risk factor for pancreatic cancer.

30 Aug 2022

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Researchers identify and characterize the targets of Vit D on COVID-19 and osteoporosis.

30 Aug 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

Using human tissue models to improve treatment and diagnosis of heart attacks

A heart attack, or myocardial infarction, is one of the leading causes of mortality worldwide, resulting in 18 million deaths per year.

30 Aug 2022

Study reinforces the potential of Huntington’s treatments that target glia cells

Huntington's disease – a hereditary and fatal genetic disorder – has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical hallmarks of the disease: involuntary movements, problems with coordination, cognitive decline, depression, and psychosis.

30 Aug 2022

A simple and low-cost method to identify valve dysfunction

Aortic valve stenosis occurs when the aortic valve narrows, constricting blood flow from the heart through the artery and to the entire body.

30 Aug 2022

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer - at an early enough stage that cure is possible.

30 Aug 2022

Researchers identify potential new pathway for treating a sporadic form of ALS

Researchers have published two papers describing how they identified a potential new pathway for treating a sporadic form of amyotrophic lateral sclerosis (ALS).

30 Aug 2022

$Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures$

Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures

Aging is universal. Both osteoporosis and the bone fractures that occur as a result of osteoporosis become more likely with age.

30 Aug 2022

Study sheds new light on the nature of balance deficits in neurocognitive disorders

Balance is important to maintain in many aspects of life, but the most important may be your body's sense of balance—also known as vestibular sense—which keeps you upright when moving or standing.

30 Aug 2022

New study aims to help people with learning disabilities to fight loneliness

People with learning disabilities are set to benefit from a new study, funded by the NIHR, by the University of Surrey that will examine ways to help them overcome loneliness - which often leads to other underlying medical issues such as heart diseases, obesity, anxiety, and depression.

30 Aug 2022

Using deep learning to guide the selection of chemotherapy after surgery for colorectal cancer patients

Among patients with colorectal cancer spread to lymph nodes, a deep learning marker can identify one-third with excellent prognosis and consequently no need for adjuvant chemotherapy.

30 Aug 2022

Gothenburg scientists discover possible new cancer treatment target

Researchers at the University of Gothenburg have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice.

30 Aug 2022

AI proves to be more accurate in diagnosing cardiac function than sonographers

In a first-of-its-kind randomized clinical trial led by researchers at the Smidt Heart Institute and the Division of Artificial Intelligence in Medicine at Cedars-Sinai, artificial intelligence (AI) proved more successful in assessing and diagnosing cardiac function when compared to echocardiogram assessments made by sonographers.

29 Aug 2022

Men who have sex with men adopting protective measures against monkeypox virus

The U.S. Centers for Disease Control and Prevention (CDC) recently published the results of a survey specific to monkeypox virus (MPV) infection associated with the American Men's Internet Survey (AMIS) in the Morbidity and Mortality Weekly Report (MMWR).

29 Aug 2022

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strategy to overcome tumor-induced immunosuppression.

29 Aug 2022

Gay, and bisexual men changing sexual behavior to reduce risk of monkeypox

A study conducted by scientists from the US Centers for Disease Control and Prevention (CDC) indicates that reducing one-time sexual partnerships among gay, bisexual, and other men who have sex with men can significantly reduce the transmission of the monkeypox virus.

29 Aug 2022

Medical Condition News

Immune cells beyond CAR-T cells affect the durability of response to BCMA CAR T therapy in myeloma

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

Abdominal obesity increases risk of pancreatic cancer

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Study reveals a vital route through which fascin promotes cancer development

Using human tissue models to improve treatment and diagnosis of heart attacks

Study reinforces the potential of Huntington’s treatments that target glia cells

A simple and low-cost method to identify valve dysfunction

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Researchers identify potential new pathway for treating a sporadic form of ALS

Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures

Study sheds new light on the nature of balance deficits in neurocognitive disorders

New study aims to help people with learning disabilities to fight loneliness

Using deep learning to guide the selection of chemotherapy after surgery for colorectal cancer patients

Gothenburg scientists discover possible new cancer treatment target

AI proves to be more accurate in diagnosing cardiac function than sonographers

Men who have sex with men adopting protective measures against monkeypox virus

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

Gay, and bisexual men changing sexual behavior to reduce risk of monkeypox

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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