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U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

University of Utah Health researchers are leading a five-year, $22-million nationwide clinical trial for NMDA receptor encephalitis––a type of autoimmune encephalitis that prompts the immune system to mistakenly attack the brain, causing confusion, memory loss, seizures, and symptoms similar to bipolar disorder and other psychiatric conditions.

1 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this.

1 Mar 2022

€10 million ‘precision medicine’ research project launched to provide new insights into ALS

An ambitious academic, clinical and industry research programme that will provide new insights into our understanding of Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS), was launched today by Tánaiste and Irish Minister for Enterprise, Trade and Employment, Leo Varadkar T.D.

1 Mar 2022

mRNA vaccines found to generate neutralizing antibodies against SARS-CoV-2 Omicron variant

A new study assessed the immunogenicity of messenger-ribonucleic acid vaccines to generate cross-reactive neutralizing antibodies against the SARS-CoV-2 Omicron variant in convalescent COVID-19 patients.

1 Mar 2022

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.

1 Mar 2022

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

In a new study, researchers developed and elucidated a ‘bridge integration’ method to harmonize single-cell ribonucleic acid sequencing datasets.

1 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

Study finds striking variations in SARS-CoV-2-related mortalities in North and South regions of the USA

In a new study, researchers estimated the COVID-19-associated mortality in the United States between January 3, 2020, and September 26, 2021.

1 Mar 2022

Study reveals how the immune system can be triggered to attack cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

1 Mar 2022

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

A University of Cincinnati clinical trial that added an immunotherapy drug to standard of care treatment regimens has shown increased survival rates for head and neck cancer patients with intermediate risk features.

1 Mar 2022

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the impact of an amyloidogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein fragment named SFYVYSRVK (SK9) on the α-synuclein (aS) monomers and fibrils, a potential risk factor for Parkinson's disease.

28 Feb 2022

COVID-19 severity is correlated with body composition

In a recent study posted to the medRxiv* preprint server, researchers assessed the effect of changes in the abdominal well-being and physique on coronavirus disease 2019 (COVID-19) severity using magnetic resonance imaging (MRI).

28 Feb 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

First platform trial for ALS hopes to accelerate the development of effective treatments

A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial– the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness.

28 Feb 2022

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of their updated guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty.

28 Feb 2022

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Even though Dry January is over, new research suggests you may want to consider keeping the no-alcohol challenge going all year, especially if you're among the nearly 2 million Americans who have age-related macular degeneration (AMD), a sight-threatening eye condition.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Medical Condition News

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

AI and machine learning could improve cancer diagnosis through biomarker discovery

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

€10 million ‘precision medicine’ research project launched to provide new insights into ALS

mRNA vaccines found to generate neutralizing antibodies against SARS-CoV-2 Omicron variant

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

Study finds striking variations in SARS-CoV-2-related mortalities in North and South regions of the USA

Study reveals how the immune system can be triggered to attack cancer cells

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

COVID-19 severity is correlated with body composition

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Study compares heterologous and homologous third vaccination in kidney transplant recipients

First platform trial for ALS hopes to accelerate the development of effective treatments

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Novel molecular pathway shared by two neurodegenerative disorders discovered

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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