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Research opens new avenues for topical treatment of skin fibrosis

Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess.

21 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

Study reveals dual role of anti-cancer inhibitor

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells, according to a Northwestern Medicine study published in the Journal for Immunotherapy of Cancer.

21 Oct 2021

More than 50% of space travelers experience back pain, experts say

With growing numbers of humans venturing into space, experts predict an increase in the number of people experiencing the physical toll of such travel, including highly common forms of back pain.

21 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Antidepressant Prozac could offer the first treatment for atrophic macular degeneration

An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine suggests.

21 Oct 2021

Study analyzes neural correlates of balance in individuals with traumatic brain injury

Using neuroimaging techniques and electroencephalography (EEG), Kessler Foundation researchers compared the neural correlates of balance in individuals with traumatic brain injury and matched controls. This study is the first to report EEG-based functional connectivity measures during a balance perturbation task and show the association with white matter integrity in the brain.

21 Oct 2021

Study highlights major role of polysubstance use in drug overdose risk

Even as the opioid epidemic dominated national attention over the past decade, the rate of overdose deaths involving cocaine, methamphetamine and other stimulants tripled, a new study in veterans suggests.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night. Scientists already know that our metabolic health can suffer when our biological clock breaks down, due to shift work or sleep disorders, for example. However, it's unclear how exactly the biological clock of people with type 2 diabetes differs from healthy people.

21 Oct 2021

Drug company pipelines are filling up with new molecules to help people lose weight

Drugs that promise to help people lose weight have had a checkered past, such as the infamous fen-phen that was pulled from the market in 1997 after reports of heart valve damage. But now, drug company pipelines are filling up with new molecules that aim to help people safely shed extra pounds, according to a cover story in Chemical & Engineering News, an independent news outlet of the American Chemical Society.

21 Oct 2021

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.

21 Oct 2021

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Targeting the dentate nucleus with deep brain stimulation (DBS) was safe and feasible for promoting post-stroke rehabilitation in a first-in-human study at Cleveland Clinic.

21 Oct 2021

Playing elite rugby may affect cognitive function in older age, study shows

Retired male elite rugby union players aged 50+ who suffered three or more rugby-related concussions during their career have no worse average cognitive function than those who had experienced no, one or two concussions, according to a new study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

21 Oct 2021

Study paves the way for development of new therapeutic strategies to treat addiction

Drug addiction is a psychiatric disorder for which no pharmacological treatment with long-term efficacy currently exists. All addictive substances share the property of raising concentrations of the neurotransmitter dopamine within brain regions forming the neural reward circuit.

21 Oct 2021

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body.

20 Oct 2021

MRI study suggests link between SARS-CoV-2 and brain lesions in COVID-19 patients with pneumonia

New research suggests pneumonia in COVID-19 patients is linked to viral-induced changes in the brain. MRI scans revealed 57.9% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients had recent brain lesions.

20 Oct 2021

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

20 Oct 2021

Personalized clotting profiles could benefit people at risk from strokes and heart attacks

People at risk from strokes and heart attacks could benefit from personalized clotting profiles to help clinicians prescribe more precise treatments, thanks to new research.

20 Oct 2021

Discovery could lead to new treatments for axial spondyloarthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network in Toronto, have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which affects 1-2% of Canadians and causes inflammation in the spine, joints, eyes, gut and skin.

20 Oct 2021

Medical Condition News

Research opens new avenues for topical treatment of skin fibrosis

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Study reveals dual role of anti-cancer inhibitor

More than 50% of space travelers experience back pain, experts say

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

Antidepressant Prozac could offer the first treatment for atrophic macular degeneration

Study analyzes neural correlates of balance in individuals with traumatic brain injury

Study highlights major role of polysubstance use in drug overdose risk

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Drug company pipelines are filling up with new molecules to help people lose weight

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Playing elite rugby may affect cognitive function in older age, study shows

Study paves the way for development of new therapeutic strategies to treat addiction

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

MRI study suggests link between SARS-CoV-2 and brain lesions in COVID-19 patients with pneumonia

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Personalized clotting profiles could benefit people at risk from strokes and heart attacks

Discovery could lead to new treatments for axial spondyloarthritis

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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