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Promising results of combination treatment for acute myeloid leukemia to be presented at ASCO 2022

On Tuesday, June 7, Eunice Wang, MD, Chief of Leukemia at Roswell Park Comprehensive Cancer Center, will present the long-term results of a phase 2 clinical trial combining crenolanib, a second-generation FLT3 inhibitor, with standard intensive chemotherapy for treatment of adults with newly diagnosed FLT3-mutant acute myeloid leukemia (AML).

6 Jun 2022

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer.

6 Jun 2022

Medication and lifestyle changes improve dizziness in pediatric long-COVID patients

A new Pediatrics study describes the experience of treating pediatric PASC patients with persistent dizziness.

6 Jun 2022

Combining psychotherapy with antidepressants does not improve outcomes in severely depressed patients

Antidepressants are the first-choice treatment for severe depression. Antidepressant use is often supplemented by psychotherapy.

6 Jun 2022

COVID-19 patients have increased risk of new‐onset psychiatric disorders after infection

A recent Oregon State University study found that COVID-19 patients had a roughly 25% increased risk of developing a psychiatric disorder in the four months following their infection, compared with people who had other types of respiratory tract infections.

6 Jun 2022

Moderate to severe sleep disturbances found to be prevalent among patients with long COVID

Cleveland Clinic researchers found more than 40% of patients with Long COVID (Post-Acute Sequelae of COVID-19 or PASC) had moderate to severe sleep disturbances.

6 Jun 2022

Autoantibody found to cause schizophrenia-like behaviors in mice

Schizophrenia is a disorder that affects how people act, think, and perceive reality. It is often very difficult to treat because it has many different causes and symptoms.

6 Jun 2022

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Patients with multiple myeloma who have been treated with a three-drug combination therapy have a growing number of choices for subsequent treatment. Results of a new study led by researchers at Dana-Farber Cancer Institute can help patients and their physicians weigh benefits and risks of each option.

6 Jun 2022

Diabetes-tailored program produces meaningful effects on glycemic control, body weight

Study results from three clinical trial sites show that a WW International, Inc. ("WeightWatchers" or "WW") program tailored for people living with diabetes helped participants lose weight, lower blood glucose levels, and improve their overall well-being.

6 Jun 2022

Chemo-immunotherapy combination shows promise against pancreatic cancer

A combination of chemotherapy with an immunotherapy meant to unleash the anticancer capacity of the immune system was effective against one of the hardest targets in cancer care, pancreatic cancer, in a national, randomized clinical trial led by researchers at the Perelman School of Medicine at the University of Pennsylvania, and sponsored by the Parker Institute for Cancer Immunotherapy.

6 Jun 2022

Children with leukemia have higher survival than adolescents and young adults with the same cancer

Children (0-14 years) diagnosed with leukemia have benefited from decades of research to improve outcomes, and their five-year survival has increased more than that of adolescents (15-19 years) and young adults (20-24 years), suggests new research published in The Lancet Child and Adolescent Health.

6 Jun 2022

Electronic symptom monitoring improved quality-of-life outcomes among patients with metastatic cancer

People with advanced cancer who communicated their symptoms weekly using an electronic survey had about a one-third better physical function and over a 15% better control of their symptoms compared to those who were evaluated less frequently via in-person clinical visits, according to findings from a multi-state study conducted at 52 community cancer clinics.

6 Jun 2022

Hospice patients with dementia more likely to receive excellent care, study shows

While the hospice program was originally designed for patients with cancer, who are expected to die within six months, currently close to half of older adult hospice enrollees have a diagnosis of dementia.

6 Jun 2022

Poor sleep may be a good predictor of COPD flare-ups

Poor sleep is associated with a significantly increased risk of life-threatening flare-ups in people with chronic obstructive pulmonary disease, or COPD, according to a new study supported by the National Institutes of Health.

6 Jun 2022

Drug combination yields highest response and longest survival rates for patients with pancreatic NETs

Very few treatment options are available to patients with advanced pancreatic neuroendocrine tumors (NETs), but researchers at the Yale Cancer Center and Yale New Haven Health's Smilow Cancer Hospital found that patients treated with a combination of capecitabine and temozolomide had longer progression-free survival rates than those treated with temozolomide alone.

6 Jun 2022

New analytical method sheds light on enduring mystery about type 2 diabetes

Researchers at Oregon State University have invented a new analytical method that sheds light on an enduring mystery regarding type 2 diabetes: Why some obese patients develop the disease and others don't.

6 Jun 2022

She’s 31, has stage 4 kidney cancer — and talked openly about it in a job interview

Katie Coleman stood face-to-face with a choice no job seeker should ever have to make. She could tell her prospective employer she had stage 4 kidney cancer, the most life-threatening stage of all.

6 Jun 2022

Physical activity and long COVID symptoms

In a recent study posted to the medRxiv* preprint server, researchers evaluated associations between physical activity and long coronavirus disease (COVID) symptoms.

6 Jun 2022

Height increases risk of certain diseases

In a recent study published in the Journal PLoS Genetics, researchers investigated how height determined several common clinical traits in adults by comparing associations of those traits with actual- and genetically-predicted-height.

5 Jun 2022

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

In a study of patients with high-risk renal cell carcinoma, those who took the drug everolimus daily for up to one year after surgery lived longer without their disease returning (recurrence-free survival, or RFS) than those who did not take everolimus, although the results narrowly missed the clinical trial's prespecified level for statistical significance.

4 Jun 2022

Medical Condition News

Promising results of combination treatment for acute myeloid leukemia to be presented at ASCO 2022

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Medication and lifestyle changes improve dizziness in pediatric long-COVID patients

Combining psychotherapy with antidepressants does not improve outcomes in severely depressed patients

COVID-19 patients have increased risk of new‐onset psychiatric disorders after infection

Moderate to severe sleep disturbances found to be prevalent among patients with long COVID

Autoantibody found to cause schizophrenia-like behaviors in mice

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Diabetes-tailored program produces meaningful effects on glycemic control, body weight

Chemo-immunotherapy combination shows promise against pancreatic cancer

Children with leukemia have higher survival than adolescents and young adults with the same cancer

Electronic symptom monitoring improved quality-of-life outcomes among patients with metastatic cancer

Hospice patients with dementia more likely to receive excellent care, study shows

Poor sleep may be a good predictor of COPD flare-ups

Drug combination yields highest response and longest survival rates for patients with pancreatic NETs

New analytical method sheds light on enduring mystery about type 2 diabetes

She’s 31, has stage 4 kidney cancer — and talked openly about it in a job interview

Physical activity and long COVID symptoms

Height increases risk of certain diseases

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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