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Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative diseases

31 Jan 2021

COVID effect resulted in substantial decline in heart surgery, caused more patient deaths

The most deadly global health crisis in a century has resulted in a substantial decline in overall heart surgery volume and an unexplained increase in deaths after coronary artery bypass grafting, according to late-breaking research presented at the 57th Annual Meeting of The Society of Thoracic Surgeons.

31 Jan 2021

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

To better understand how low blood oxygen level, or hypoxemia, and lung compliance varies in COVIDARDS and how they relate to disease outcomes, researchers developed a dataset of using more than 11,000 COVID-19 patients admitted to the hospital. A research paper published on the medRxiv* preprint server reports their results.

31 Jan 2021

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.

30 Jan 2021

Researchers examine the connection between lung cancer and COVID-19

On February 27, 2020, the flagship journal of the International Association for the Study of Lung Cancer, the Journal of Thoracic Oncology, published a case study that described two patients from Wuhan, China who recently underwent lung lobectomies for adenocarcinoma and were retrospectively found to have had COVID-19 at the time of surgery.

30 Jan 2021

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies.

29 Jan 2021

Study finds locations of early prion protein accumulation in the eye

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists.

29 Jan 2021

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002.

29 Jan 2021

Robotic exoskeleton gait training may aid early rehabilitation for stroke

A team of New Jersey researchers has demonstrated that high-dose therapy gait training using robotic exoskeletons may aid early rehabilitation for acute stroke.

29 Jan 2021

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

New research from the University of Sheffield has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer's disease.

29 Jan 2021

Novel deep learning system can predict cardiovascular risk from CT scans

Coronary artery calcification -- the buildup of calcified plaque in the walls of the heart's arteries -- is an important predictor of adverse cardiovascular events like heart attacks.

29 Jan 2021

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

29 Jan 2021

Residential segregation, discriminatory practices impact outcomes of Black lung cancer patients

Structural racism thwarts a large proportion of black patients from receiving appropriate lung cancer care, resulting in worse outcomes and shorter lifespans than white patients with the disease, according to research presented at the 57th Annual Meeting of The Society of Thoracic Surgeons.

29 Jan 2021

Study shows promising outcomes of new mitral valve replacement procedure in high-risk patients

An innovative mitral valve replacement procedure shows promise for high-risk patients in a new University of Miami Miller School of Medicine study led by Joseph Lamelas, M.D., chief and program director of cardiothoracic surgery.

29 Jan 2021

SORLA protein promotes the growth of breast cancer brain metastasis

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

Researchers use new imaging technique to understand motor deficits in ALS disease

An interdisciplinary team of the Institut national de la recherche scientifique (INRS) used an innovative imaging technique for a better understanding of motor deficits in Amyotrophic Lateral Sclerosis (ALS).

29 Jan 2021

Researchers develop an easier way to deliver pancreatic cancer drugs

Researchers with the Kansas City Veterans Affairs Medical Center and North Dakota State University have designed a new way to deliver pancreatic cancer drugs that could make fighting the disease much easier.

29 Jan 2021

Top cancer organizations endorse resumption of cancer screening during COVID-19

The National Comprehensive Cancer Network® (NCCN®) and the American Cancer Society (ACS) are teaming up with leading cancer organizations across the country to endorse the resumption of cancer screening and treatment during the ongoing COVID-19 pandemic.

28 Jan 2021

Study: Targeting glycoprotein could improve response to cancer immunotherapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

28 Jan 2021

Medical Condition News

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

COVID effect resulted in substantial decline in heart surgery, caused more patient deaths

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Researchers examine the connection between lung cancer and COVID-19

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Study finds locations of early prion protein accumulation in the eye

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

Robotic exoskeleton gait training may aid early rehabilitation for stroke

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

Novel deep learning system can predict cardiovascular risk from CT scans

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Residential segregation, discriminatory practices impact outcomes of Black lung cancer patients

Study shows promising outcomes of new mitral valve replacement procedure in high-risk patients

SORLA protein promotes the growth of breast cancer brain metastasis

Researchers use new imaging technique to understand motor deficits in ALS disease

Researchers develop an easier way to deliver pancreatic cancer drugs

Top cancer organizations endorse resumption of cancer screening during COVID-19

Study: Targeting glycoprotein could improve response to cancer immunotherapy

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