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Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

A Mayo Clinic team, led by Rahmi Oklu, M.D., Ph.D., a vascular and interventional radiologist at Mayo Clinic, in collaboration with Samir Mitragotri, Ph.D., of Harvard University, report the development of a new ionic liquid formulation that killed cancer cells and allowed uniform distribution of a chemotherapy drug into liver tumors and other solid tumors in the lab.

11 Feb 2021

New review recommends a holistic approach to manage cerebral small vessel disease

Cerebral small vessel disease (SVD) is characterized by damage to the blood vessels and parenchyma in the brain. It presents as a multitude of symptoms, which makes the diagnosis difficult.

11 Feb 2021

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Scientists from Scientific and Educational Center & Smart Materials and Biomedical Applications under the leadership of Kateryna Levada together with colleagues from Center for Immunology and Cellular Biotechnology of the Immanuel Kant Baltic Federal University conducted a joint interdisciplinary study on the development of a new method for treating leukemia using nanomaterials.

11 Feb 2021

Statins shown to reduce COVID-19 severity and lower mortality

Much attention has been focused on ways to reduce the deadly exaggeration of normal inflammatory reactions to this pathogen. A new research paper posted to the medRxiv* preprint server describes the alleviation of hyper-inflammatory phenomena following the administration of statins, drugs more widely known for their use in reducing blood cholesterol levels, to patients with COVID-19.

11 Feb 2021

New algorithm can classify severity of autistic traits using brain activity data

A team of researchers from Russia and Israel applied a new algorithm to classify the severity of autistic personality traits by studying subjects' brain activity.

11 Feb 2021

Use of mobile stroke units linked to improved clinical outcomes

STEMOs (Stroke-Einsatz-Mobile) have been serving Berlin for ten years. The specialized stroke emergency response vehicles allow physicians to start treating stroke patients before they reach hospital.

11 Feb 2021

Duration of delirium in critically ill patients predicts mortality and disability

Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.

11 Feb 2021

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Sleep and health are inextricably connected. New research from investigators at Brigham and Women's Hospital explores the connection between sleep disturbances and deficiencies among older adults and risk of dementia and death, finding that risk of dementia was double among participants who reported getting less than five hours of sleep compared to those who reported 7-8 hours of sleep per night.

11 Feb 2021

Older adults can be more focused, less mentally restless than younger adults

New research from Trinity College Dublin suggests that older adults can be more focused, less impeded by anxiety and less mentally restless than younger adults.

11 Feb 2021

Study investigates influence of adequate supply of vitamin D on prognosis of numerous diseases

In recent years, three meta-analyses of clinical studies have come to the conclusion that vitamin D supplementation was associated with a reduction in the mortality rate from cancer of around 13 percent.

11 Feb 2021

Study investigates multi-enzyme complex that plays key role in metabolism

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published their findings in the journal Cell Reports.

11 Feb 2021

Scientists avert drug resistance in subtype of brain tumors

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice.

11 Feb 2021

A new method to determine how carcinogenic bacteria reach their targets

The gram-negative bacteria Helicobacter pylori (H. pylori) colonize the stomachs of the majority of the world's population.

11 Feb 2021

Cell-selective nanotherapy can help treat atherosclerotic plaques

Percutaneous coronary intervention (PCI), commonly known as angioplasty with a stent, opens clogged arteries and saves lives. Despite its benefit in treating atherosclerosis that causes coronary artery disease, this common minimally-invasive procedure still poses severe complications for some patients.

11 Feb 2021

Single strain of bacteria may reduce the severity of graft-versus-host disease

MUSC Hollings Cancer Center researchers found that a single strain of bacteria may be able to reduce the severity of graft-versus-host disease (GVHD), as reported online in February 2021 in JCI Insight.

11 Feb 2021

Researchers analyze overall survival rate of prostate cancer patients treated with melatonin

Oncotarget recently published "Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment" which reported that a retrospective study included 955 patients of various stages of prostate cancer who received combined hormone radiation treatment from 2000 to 2019.

11 Feb 2021

Researchers use cachexia model to assess cancer-derived myocardial impairments

Oncotarget recently published "Evaluation of cancer-derived myocardial impairments using a mouse model" which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder.

11 Feb 2021

New research examines how alcohol exposure impacts aspects of neuroplasticity

New research and analysis examine how alcohol exposure impacts many aspects of neuroplasticity in a special issue of Brain Plasticity

11 Feb 2021

New strategy to optimize the efficacy of neuropeptides for therapeutic applications

Dimerization (Note: combination of two identical or different molecules) of the human neuropeptides oxytocin and vasopressin can produce new types of bioactive molecules.

10 Feb 2021

Medical Condition News

Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

New review recommends a holistic approach to manage cerebral small vessel disease

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Statins shown to reduce COVID-19 severity and lower mortality

New algorithm can classify severity of autistic traits using brain activity data

Use of mobile stroke units linked to improved clinical outcomes

Duration of delirium in critically ill patients predicts mortality and disability

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Older adults can be more focused, less mentally restless than younger adults

Study investigates influence of adequate supply of vitamin D on prognosis of numerous diseases

Study investigates multi-enzyme complex that plays key role in metabolism

Scientists avert drug resistance in subtype of brain tumors

New gut microbiome-based approach may have translational potential for cancer immunotherapy

A new method to determine how carcinogenic bacteria reach their targets

Cell-selective nanotherapy can help treat atherosclerotic plaques

Single strain of bacteria may reduce the severity of graft-versus-host disease

Researchers analyze overall survival rate of prostate cancer patients treated with melatonin

Researchers use cachexia model to assess cancer-derived myocardial impairments

New research examines how alcohol exposure impacts aspects of neuroplasticity

New strategy to optimize the efficacy of neuropeptides for therapeutic applications

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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