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First-of-its-kind cardiovascular drug gets FDA approval based on study from Canadian VIGOUR Centre

The U.S. Food and Drug Administration has approved the drug vericiguat for use in patients with heart failure.

25 Jan 2021

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

Study conducted by researchers from the GIGA CRC In vivo Imaging laboratory at ULiège demonstrates, for the first time in humans, how the first deposits of tau proteins in the brainstem are associated with neurophysiological processes specific to the early stages of Alzheimer's disease development.

25 Jan 2021

Older minority cancer patients more likely to experience negative surgical outcomes

Older minority cancer patients with poor social determinants of health are significantly more likely to experience negative surgical outcomes compared to white patients with similar risk factors, according to a new study published by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

25 Jan 2021

Cancer patients more likely to die following surgery in lower-income countries

Research by an international team of medical experts has found cancer patients could be up to four times more likely to die following cancer surgery in low to lower-middle income countries than in high-income countries.

25 Jan 2021

Missing surface protein allows small cell lung cancer cells to hide from immune defenses

Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body's key cancer defenses, a new study led by UT Southwestern researchers suggests.

25 Jan 2021

Newly designed Biomesh minimizes postsurgical complications of hernia repair

Hernias are one of the most common soft tissue injuries. Hernias form when intra-abdominal content, such as a loop of the intestine, squeezes through weak, defective or injured areas of the abdominal wall.

25 Jan 2021

COVID-19 diagnostic tests remain able to detect all published virus strains

Paris, France and Camberley, UK – 21 December 2020 – Novacyt (EURONEXT GROWTH: ALNOV; AIM: NCYT), an international specialist in clinical diagnostics, announces that following the detection of a new variant of COVID-19 by the UK’s COVID19 Genomics UK consortium, known as VUI-202012/01, the Company has carried out a detailed analysis of the mutations in this new variant and in all published COVID-19 strains to fully assess the reliability of its existing diagnostic tests.

From AFSBio 25 Jan 2021

Lifestyle management with focus on innovations is key to preventing non-communicable diseases

The key factor in preventing non-communicable diseases is lifestyle management at the individual level with a focus on such innovations, which can help increase the awareness of risk factors management in society, claim an international team of researchers, among them - scientists from Kaunas University of Technology, Lithuania in a recent study.

25 Jan 2021

New modeling study shows increased future demand for cancer surgery

Public health researchers, led by UNSW Sydney, have estimated the number of cancer cases requiring surgery globally each year, predicting the number will rise from 9.1 million to 13.8 million from 2018 to 2040 - an increase of 52 per cent or 4.7 million cases.

25 Jan 2021

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

The cover for issue 2 of Oncotarget features Figure 4, "Combination therapy TA99/ICB reduced the lung tumor burden in the B16 model of metastases," published in "Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma" by Pérez-Lorenzo, et al. which reported that here, the authors showed that removing immune suppression and enhancing stimulatory signals increased the anti-tumor activity of unmodified TA99 antibodies with a significant reduction of growth of solid tumors and lung metastases in mouse models of melanoma.

25 Jan 2021

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

The cover for issue 52 of Oncotarget features Figure 1, "Volcano plots of DNA methylation in tumor tissues compared with nontumor tissue," published in "Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma" by Morine, et al. which reported that the authors conducted a genome-wide analysis of DNA methylation of the tumor and non-tumor tissue of 15 patients with Hepatocellular carcinoma (HCC), and revealed TBX15 was the most hypermethylated gene of the tumor.

25 Jan 2021

Experts advise disaggregating data on COVID-19 patients by sex

Researchers at Yale University School of Medicine have highlighted the importance of ensuring studies of patients with coronavirus disease 2019 (COVID-19) report data in a sex-disaggregated manner.

24 Jan 2021

New maintenance treatment for AML shows strong benefit for patients

Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3 clinical trial for which Weill Cornell Medicine and NewYork-Presbyterian are trial sites.

22 Jan 2021

Study examines risk factors for developing ME/CFS in college students after infectious mononucleosis

Many college students fully recover from infectious mononucleosis (which is almost always caused by Epstein-Barr virus) within 1-6 weeks, but some go on to develop chronic fatigue syndrome, also called myalgic encephalomyelitis (ME/CFS).

22 Jan 2021

First-ever systematic review to understand geographic factors that affect HPV vaccination rates

Human papillomavirus (HPV) is the most common sexually transmitted infection, with an estimated 79 million Americans currently infected with the virus, according to the Centers for Disease Control and Prevention.

22 Jan 2021

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.

22 Jan 2021

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

Dramatic changes were seen in the delivery of radiotherapy treatments for cancer during the first wave of the coronavirus pandemic in England.

22 Jan 2021

UC researchers test new combination therapy for head and neck cancer in animal models

Head and neck cancer is the sixth most common cancer worldwide, and while effective treatments exist, sadly, the cancer often returns.

22 Jan 2021

NCCN provides new guidance for COVID-19 vaccinations in people with cancer

The National Comprehensive Cancer Network put out new information today to provide guidance for COVID-19 vaccinations in people with cancer.

22 Jan 2021

Lack of sleep, stress, mental health problems can lead to PCS-like symptoms

A new study suggests that a lot of people might be going through life with symptoms that resemble concussion - a finding supporting researchers' argument that athletes recovering from a brain injury should be assessed and treated on a highly individualized basis.

22 Jan 2021

Medical Condition News

First-of-its-kind cardiovascular drug gets FDA approval based on study from Canadian VIGOUR Centre

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

Older minority cancer patients more likely to experience negative surgical outcomes

Cancer patients more likely to die following surgery in lower-income countries

Missing surface protein allows small cell lung cancer cells to hide from immune defenses

Newly designed Biomesh minimizes postsurgical complications of hernia repair

COVID-19 diagnostic tests remain able to detect all published virus strains

Lifestyle management with focus on innovations is key to preventing non-communicable diseases

New modeling study shows increased future demand for cancer surgery

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

Experts advise disaggregating data on COVID-19 patients by sex

New maintenance treatment for AML shows strong benefit for patients

Study examines risk factors for developing ME/CFS in college students after infectious mononucleosis

First-ever systematic review to understand geographic factors that affect HPV vaccination rates

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

UC researchers test new combination therapy for head and neck cancer in animal models

NCCN provides new guidance for COVID-19 vaccinations in people with cancer

Lack of sleep, stress, mental health problems can lead to PCS-like symptoms

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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