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Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is effective and well-tolerated against advanced ROS1 and NTRK fusion-positive non-small cell lung cancers (NSCLC).

14 Dec 2019

Community-based program enables donation of tumor tissue and blood samples for research

Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories and patient samples obtained before and during their treatment.

14 Dec 2019

Study shows how a protein in the brain could protect against Alzheimer’s

Research shows that white blood cells in the human brain are regulated by a protein called CD33--a finding with important implications in the fight against Alzheimer's disease, according to a new study by University of Alberta chemists.

13 Dec 2019

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing for personalized, precision treatment.

13 Dec 2019

Patient-reported outcomes linked to aromatase inhibitor adherence

If you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients commonly answer in cancer clinical trials, according to research findings to be presented Friday, Dec. 13 at the San Antonio Breast Cancer Symposium.

13 Dec 2019

Researchers find many psychiatric disorders share the same gene variants

An international team of researchers has found that many psychiatric disorders share a common and specific set of gene variants.

13 Dec 2019

New technique may lead to earlier and easier detection of mouth and throat cancer

Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced, partly because their location makes them difficult to see during routine clinical exams.

13 Dec 2019

Medications prescribed to children with chronic kidney disease may harm their kidneys

An analysis of records from primary care practices in the United Kingdom found that many children with kidney disease are prescribed medications that may be toxic to their kidneys.

13 Dec 2019

ACMG recommends evaluations of breast cancer patients before genetic testing

According to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organization's official journal, Genetics in Medicine, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.

13 Dec 2019

Caution is advised in interpreting the findings on radioiodine therapy for hyperthyroidism

Caution is advised in interpreting the findings of the recent JAMA Internal Medicine publication1 on radioactive iodine treatment for hyperthyroid patients and cancer mortality.

13 Dec 2019

Precision epigenome editing can repair genetic syndrome of intellectual disability

Using a targeted gene epigenome editing approach in the developing mouse brain, Johns Hopkins Medicine researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, which causes intellectual disability and obesity in people.

13 Dec 2019

Scientists develop new method for targeted drug delivery to cancer cells

A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells.

13 Dec 2019

New strategy could prevent side effects of targeted cancer treatment

Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor, a protein that stimulates cell proliferation.

13 Dec 2019

Women with osteoporosis feel let down by the healthcare system, survey reveals

Results from a new UCB survey have revealed the impact osteoporosis has on women, with nearly two thirds (65%) agreeing that their condition is being neglected and that their healthcare authority should be doing more to prioritize it (83%).

13 Dec 2019

Research could pave way for regenerative TBI-IV therapy

A team of researchers from the University of Georgia's Regenerative Bioscience Center has found that neural exosomes- "cargo" molecules within the nervous system that carry messages to the brain- can minimize or even avert progression of traumatic brain injury when used as part of a new cell-to-cell messaging technology.

12 Dec 2019

Oncology social workers offer advice on managing holidays with a life-threatening illness

Stringing the lights, storming the malls and all those parties! Imagine facing these holiday demands while you're tired, sick, sad and worried: for people with cancer or other life-threatening illnesses, this time of year can often be far from merry.

12 Dec 2019

Computerized CBT for depression could improve access to treatment, reduce waiting lists

Using a computerised version of cognitive-behavioural therapy to treat depression in children and young adults has the potential to improve access to psychological therapies and reduce waiting lists, a new study suggests.

12 Dec 2019

Gulf war illness – one or two diseases?

A study of veterans who have Gulf war syndrome shows that moderate exercise can bring about a spectrum of brain imaging abnormalities, which fall into one of two groups. This could mean that this is a more complicated illness than was first thought. The study was published on December 12, 2019, in the journal Brain Communications.

12 Dec 2019

Scientists develop an approach to vaccinate against gut inflammation

Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied to certain alternations in the gut flora.

12 Dec 2019

Skip the sweet treats to avoid holiday blues, study suggests

If you're prone to depression, this holiday season you might want to say "bah humbug" to offers of sugar plum pudding, caramel corn and chocolate babka.

12 Dec 2019

Medical Condition News

Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Community-based program enables donation of tumor tissue and blood samples for research

Study shows how a protein in the brain could protect against Alzheimer’s

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Patient-reported outcomes linked to aromatase inhibitor adherence

Researchers find many psychiatric disorders share the same gene variants

New technique may lead to earlier and easier detection of mouth and throat cancer

Medications prescribed to children with chronic kidney disease may harm their kidneys

ACMG recommends evaluations of breast cancer patients before genetic testing

Caution is advised in interpreting the findings on radioiodine therapy for hyperthyroidism

Precision epigenome editing can repair genetic syndrome of intellectual disability

Scientists develop new method for targeted drug delivery to cancer cells

New strategy could prevent side effects of targeted cancer treatment

Women with osteoporosis feel let down by the healthcare system, survey reveals

Research could pave way for regenerative TBI-IV therapy

Oncology social workers offer advice on managing holidays with a life-threatening illness

Computerized CBT for depression could improve access to treatment, reduce waiting lists

Gulf war illness – one or two diseases?

Scientists develop an approach to vaccinate against gut inflammation

Skip the sweet treats to avoid holiday blues, study suggests

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